Your Best Shot: The Personalized System for Optimal Weight Health―GLP-1 Shot or Not - Hardcover

Koff RD, Ashley

Hardcover

ISBN 10: 0063444186 ISBN 13: 9780063444188

Publisher: HarperOne, 2026

Synopsis

USA Today Bestseller

Why have you struggled with your weight, even when you did "everything right"? The answer isn't willpower or diet, and it's not you. Your Best Shot provides the tools to optimize your weight-health hormones permanently, whether you have never used a GLP-1 medication, are currently using one, or are ready to come off one.

Here's the insight that's reshaping medicine: GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound work because the body regulates appetite, metabolism, blood sugar, and fat storage through a sophisticated hormonal system. If a medication helped you lose weight or curb cravings, it means your own weight-health hormones weren't functioning at their best. That's not a personal failure. That's biology, and it's fixable—with or without the shot.
Registered dietitian and weight health pioneer Ashley Koff, RD has spent over two decades in clinical practice developing a system that finally addresses why weight loss doesn't often work long-term, and what actually does. The result is an evidence-based, personalized program that meets you exactly where you are.

This is not another weight loss plan. This is your plan.

With Your Best Shot, you will:

• Identify why your weight-health hormone function isn’t optimal—and how to fix it
• Personalize the nutrition and lifestyle plan with food, supplement, activity, and sleep guidelines
• Eliminate food noise and decision fatigue by finding out what information to ignore and what to trust
• Navigate the landscape of GLP-1 medications, supplements, and foods
• Build a sustainable reset, because life happens, so your plan needs to adjust with it

Your Best Shot is essential for the millions of people using GLP-1s who want to maximize their results, protect their progress, and build a foundation that lasts long after the medication. It is also the definitive guide for anyone considering coming off GLP-1 therapy who needs a plan that works without it.

If you've struggled with weight, cravings, energy, or body composition, this book was written for you.

About this title

About the Author

Ashley Koff, RD, is a leading voice in personalized nutrition and the founder of The Better Nutrition Program. With over twenty-five years of experience and the groundbreaking GLP-1 Optimization™ system to her name, she’s helped redefine how we approach sustainable, lasting weight health. A trusted expert featured across major media and a sought-after educator for health professionals, Ashley blends cutting-edge science with everyday practicality. When she’s not transforming lives, she’s recharging in nature with her dog Roger, cheering courtside for her favorite basketball teams, or savoring time with loved ones.

Edition details

• Publisher: HarperOne
• Publication date: 2026
• Language: English
• ISBN 10: 0063444186
• ISBN 13: 9780063444188
• Binding: Hardcover
• Number of pages: 368