Commemorating the 40th anniversary of discovering what was then called sulfation factor and later somatomedin, researchers exchange their recent findings in 45 papers. They cover the four decades of research on the regulation of cartilage growth, physiological and therapeutic aspects of IGF-I relating to diabetes and the heart, the regulation of gene expression and synthesis of IGF and IGFBP, the regulation of IGFBP action, the tissue-specific regulation of activity, signal transduction, the factor's role in disease and a possible clinical application, and directions for research. No subject index. Annotation c. by Book News, Inc., Portland, Or.
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