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Published by CRC Press, 2000
ISBN 10: 0824703944ISBN 13: 9780824703943
Seller: HPB-Red, Dallas, TX, U.S.A.
Book
hardcover. Condition: Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority!.
Published by CRC Press, 2000
ISBN 10: 0824703944ISBN 13: 9780824703943
Seller: ThriftBooks-Atlanta, AUSTELL, GA, U.S.A.
Book
Hardcover. Condition: As New. No Jacket. Pages are clean and are not marred by notes or folds of any kind. ~ ThriftBooks: Read More, Spend Less 1.09.
Published by CRC Press, 2000
ISBN 10: 0824703944ISBN 13: 9780824703943
Seller: Buyback Express, Alton, IL, U.S.A.
Book
Hardcover. Condition: Good. Good Condition. Reasonable wear. Still very usable. Clean, mark-free interior! SHIPS WITHIN 24 HOURS! Free Tracking & Insurance! Premium Carrier processing & USPS final delivery for an average of 3-5 Day Standard & 2-3 Day Expedited! FREE INSURANCE! Fast & Personal Support! Careful Packaging. No Hassle, Full Refund Return Policy!.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659159107ISBN 13: 9783659159107
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
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Condition: New.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: booksXpress, Bayonne, NJ, U.S.A.
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Soft Cover. Condition: new.
Published by Taylor & Francis Group, 2000
ISBN 10: 0824703944ISBN 13: 9780824703943
Seller: Books Puddle, New York, NY, U.S.A.
Book
Condition: Used. pp. x + 248 1st Edition.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Book
Condition: New.
Published by Taylor & Francis Group, 2000
ISBN 10: 0824703944ISBN 13: 9780824703943
Seller: Majestic Books, Hounslow, United Kingdom
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Condition: Used. pp. x + 248 Illus. This item is printed on demand.
Published by Kluwer Academic / Plenum Publishers, 2001
ISBN 10: 0306467089ISBN 13: 9780306467080
Seller: Ammareal, Morangis, France
Book
Hardcover. Condition: Très bon. Légères traces d'usure sur la couverture. Edition 2001. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Slight signs of wear on the cover. Edition 2001. Ammareal gives back up to 15% of this item's net price to charity organizations.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Book
Condition: As New. Unread book in perfect condition.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659159107ISBN 13: 9783659159107
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
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PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by CRC Press 2019-09-05, Boca Raton, 2019
ISBN 10: 0367398664ISBN 13: 9780367398668
Seller: Blackwell's, London, United Kingdom
Book
paperback. Condition: New. Language: ENG.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: GreatBookPricesUK, Castle Donington, DERBY, United Kingdom
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Condition: New.
Published by Mdpi AG, 2024
ISBN 10: 3725806802ISBN 13: 9783725806805
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Book
Condition: As New. Unread book in perfect condition.
Published by Mdpi AG, 2024
ISBN 10: 3725806802ISBN 13: 9783725806805
Seller: GreatBookPrices, Columbia, MD, U.S.A.
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Condition: New.
Published by Mdpi AG, 2024
ISBN 10: 3725806802ISBN 13: 9783725806805
Seller: Grand Eagle Retail, Wilmington, DE, U.S.A.
Book
Hardcover. Condition: new. Hardcover. It is well known that the blood-brain barrier (BBB), substantially composed of tight junctions between the capillary endothelial cells and efflux transporters such as MDR1 at the apical membrane of the capillary endothelial cells, prevents drugs from entering the brain. Accordingly, drug delivery into the brain across the BBB is a challenging task, particularly in central nervous system diseases such as Alzheimer's disease and Parkinson's disease, as well as brain cancers such as glioma. It is true that drugs in systemic circulation go through intentional membrane disruption or intentional tight junction disruption into the brain across the BBB, but bystander harmful compounds can enter the brain together. Moreover, although craniotomy is often conducted for surgical removal or direct drug administration, this process burdens and torments patients. Thus, non-invasive, device-mediated brain drug delivery across the BBB should be developed to improve not only patient health, but also quality of life. At present, brain drug delivery systems that utilize biological transport machineries such as carrier-mediated transport, receptor-mediated transcytosis, lipid-raft-mediated transcytosis, or macropinocytosis at the BBB have been extensively investigated. This Special Issue aims to share recent progress and trends in this field. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
Published by Springer-Verlag New York Inc., 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
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Paperback / softback. Condition: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.
Published by Mdpi AG, 2024
ISBN 10: 3725806802ISBN 13: 9783725806805
Seller: California Books, Miami, FL, U.S.A.
Book
Condition: New.
Published by CRC Press, 2019
ISBN 10: 0367398664ISBN 13: 9780367398668
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Book
Condition: New.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659159107ISBN 13: 9783659159107
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Book Print on Demand
PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Taylor & Francis Ltd, 2019
ISBN 10: 0367398664ISBN 13: 9780367398668
Seller: THE SAINT BOOKSTORE, Southport, United Kingdom
Book
Paperback / softback. Condition: New. New copy - Usually dispatched within 4 working days.
Published by Springer, 2002
ISBN 10: 0306467089ISBN 13: 9780306467080
Seller: Basi6 International, Irving, TX, U.S.A.
Book
Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Published by LAP Lambert Academic Publishing, 2012
ISBN 10: 3659159107ISBN 13: 9783659159107
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book Print on Demand
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The brain is a delicate organ, and evolution built very efficient ways to protect it. Unfortunately, the same mechanisms that protect it against intrusive chemicals can also frustrate therapeutic interventions. Many existing pharmaceuticals are rendered ineffective in the treatment of cerebral diseases due to our inability to effectively deliver and sustain them within the brain. General methods that can enhance drug delivery to the brain are, therefore, of great interest. The clinical failure of much potentially effective therapeutics is often not due to a lack of drug potency but rather to shortcomings in the method by which the drug is delivered. In response to the insufficiency in conventional delivery mechanisms, aggressive research efforts have recently focused on the development of new strategies to more effectively deliver drug molecules to the CNS.
Published by Springer, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: GreatBookPricesUK, Castle Donington, DERBY, United Kingdom
Book
Condition: As New. Unread book in perfect condition.
Published by CRC Pr I Llc, 2019
ISBN 10: 0367398664ISBN 13: 9780367398668
Seller: Revaluation Books, Exeter, United Kingdom
Book Print on Demand
Paperback. Condition: Brand New. 264 pages. 9.02x5.98x0.55 inches. In Stock. This item is printed on demand.
Published by CRC Press, 2019
ISBN 10: 0367398664ISBN 13: 9780367398668
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Book
Condition: As New. Unread book in perfect condition.
Published by CRC Press, 2019
ISBN 10: 0367398664ISBN 13: 9780367398668
Seller: GreatBookPricesUK, Castle Donington, DERBY, United Kingdom
Book
Condition: New.
Published by Springer US, 2012
ISBN 10: 1461351413ISBN 13: 9781461351412
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The vasculature of the central nervous system (eNS) is characterized by the existence of the blood-brain barrier (BBB), which can be regarded as both an anatomical and physiological phenomenon. The BBB is formed by a complex cellular system of endothelial cells, astroglia, pericytes, perivascular macrophages and a basal membrane, although the anatomic substrate of the BBB is the interendothelial tight junctions that form a continuous sealing. The BBB serves as an exquisitely controlled, functional gate to the eNS. It not only protects the brain from agents in the blood that could impair neurological function, but also controls the influx and efflux of numerous substances to maintain proper homeostasis and provide the brain with necessary nutrients. The structural and functional integrity of the BBB was shown to be dramatically altered during various diseases of the eNS, including neoplasia, ischemia, trauma, hypertension, inflammation and epilepsy. Recent years research has partially elucidated the mechanisms underlying the development of some of these brain disorders as well as the pathways used by different pathogens, like bacteria and viruses, to initiate eNS infections. The development of in vitro models of the BBB had instrumental role in the understanding of the involvement of the BBB in the pathogenesis of several eNS diseases. The intimate, functional association between the function of the brain and the activity of the BBB makes the later a target for pharmacological modulation that will expand the therapeutic possibilities for a range of neurological diseases.