Thermodynamics of Biochemical Reactions (Chemistry) - Hardcover

Alberty, Robert A.

Hardcover

ISBN 10: 0471228516 ISBN 13: 9780471228516

Publisher: Wiley-Interscience, 2003

Synopsis

Thermodynamics of Biochemical Reactions emphasizes the fundamental equations of thermodynamics and the application of these equations to systems of biochemical reactions. This emphasis leads to new thermodynamic potentials that provide criteria for spontaneous change and equilibrium under the conditions in a living cell.

About this title

Review:

"Through the writing of his new book, Professor Alberty has performed a great service to future textbook authors and to their readers, as well as to the biochemical community in general." (Biochemistry and Molecular Education, Nov/Dec 2003) "...a useful learning device...through the writing of his new book, Professor Alberty has performed a great service to future textbook authors and their readers, as well as to the biochemical community in general." (Biochemistry and Molecular Biology Education, Vol. 31, No. 6) "...this book will prove useful for students and working biochemists...highly recommended..." (Choice, September 2003) "...emphasizes the application of the fundamental equations of thermodynamics to systems of enzyme-catalyzed reactions making up the metabolism of living organisms." (Pharmaceutical Research, Vol. 20, No. 9, September 2003) "...written by the most experienced authority in this field...well-written and -organized, and nicely produced..." (Angewandte Chemie International Edition, Vol 42(37), 2003) "...the authors are to be congratulated on producing an updated, valuable and comprehensive review of the field..." (ChemPhysChem, Vol 5, 2004)

From the Back Cover:

An innovative text with a focus on metabolism and enzyme-catalyzed reactions

An excellent teaching text and resource with modern examples and references to the primary literature, Thermodynamics of Biochemical Reactions emphasizes the fundamental equations of thermodynamics and the application of these equations to systems of biochemical reactions. This emphasis leads to new thermodynamic potentials that provide criteria for spontaneous change and equilibrium under the conditions in a living cell.

The theme of the book is that Legendre transforms make the application of thermodynamics more convenient for the users. In Chapter 4, "Thermodynamics of Biochemical Reactions at Specified pH," a Legendre transform is used to introduce pH and pMg as independent intensive variables. In Chapter 6, "Systems of Biochemical Reactions," the steady-state concentrations of various coenzymes are introduced as independent intensive variables in discussing systems of enzyme-catalyzed reactions. In Chapter 8, "Phase Equilibrium in Aqueous Systems," a Legendre transform is used to introduce the electric potential of a phase as an independent intensive variable. Each instance illustrates the author?s belief that the choice of variables, while seemingly an innocuous step, often plays a critical role in formulating a solution. Other chapters include:

• Chemical Equilibrium in One-Phase Systems
• Thermodynamics of Binding of Ligands by Proteins
• Redox Reactions
• Use of Semigrand Partition Functions

Practicing researchers in pharmaceutical and biotechnical corporations, as well as graduate and upper level undergraduate students in biophysical chemistry or biochemistry, will find Thermodynamics of Biochemical Reactions to be a peerless resource.

About this edition

• Publisher: Wiley-Interscience
• Publication date: 2003
• ISBN 10: 0471228516
• ISBN 13: 9780471228516
• Binding: Hardcover
• Edition number: 1
• Number of pages: 416