Designed to acquaint biochemists, biophysicists, and graduate students with advances in the application of high pressure in connection with spectroscopy as a research tool in the study of biomolecules. The first volume devoted exclusively to high-pressure effects in biochemistry.
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a fascinating book which should attract the attention of all 'modern' scientists eager to go farther and to design project insights in still not, or only poorely exploited parts of the physical science, but which, at the end, enfold in a very large and united discipline. (R Wegmann)
The data are up-to-date and comprehensive ... the latest data included reveal an author who has much experience of working in the field of high pressure bioscience and biotechnology ... I would recommend this book for both personal or institutional purchase. (Fumiyoshi Abe, SGM Quarterly)
Written by the best researchers in the field, this timely book explores the use of high pressure in connection with spectroscopy as a research tool in biophysics and biochemistry. It covers subjects such as pressure tunning spectroscopy for investigating molecular interactions; high-pressure FT-IR studies of the secondary structure of proteins; structural, functional, and kinetic aspects of nucleic acid-protein complexes with pressure; sequence, salt, charge, and the stability of DNA at high pressure; steady-state enzyme kinetics at high pressure; membrane-free volume with bulky lipid concentration by regular distribution; and pressure and temperature induced inactivation of microorganisms.
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