Hydrogen Bonding in Organic Synthesis - Hardcover

Hardcover

ISBN 10: 352731895X ISBN 13: 9783527318957

Publisher: Wiley-VCH, 2009

Synopsis

This first comprehensive overview of the rapidly growing field emphasizes the use of hydrogen bonding as a tool for organic synthesis, especially catalysis. As such, it covers such topics as enzyme chemistry, organocatalysis and total synthesis, all unified by the unique advantages of hydrogen bonding in the construction of complex molecules from simple precursors. Providing everything you need to know, this is a definite must for every synthetic chemist in academia and industry.

About this title

Review:

"Hydrogen Bonding in Organic Synthesis is well organized and delivered in a way easy for every synthetic chemist in academia and industry to understand." (Current Engineering Practice, 1 November 2010)

"The material is well-organized and recent." (JACS Reviews, 2010)

From the Back Cover:

Snow and ice, water droplets, and all key materials of life -- the double strands of DNA and all proteins -- are held together by intermolecular forces called hydrogen bonds. These bonds, although weaker than bonds within molecules, are still strong enough to chaperone molecules into desired orientations, allowing chemists to use them as tools to perform reactions with high selectivity. In addition, hydrogen bonding can lead to metal-free catalysts, thus saving chemicals and energy in an otherwise lengthy purification process while also reducing the heavy metal output in the environment.

This first comprehensive overview of the rapidly growing field emphasizes the use of hydrogen bonding as a tool for organic synthesis, especially catalysis. As such, it covers such topics as enzyme chemistry, organocatalysis and total synthesis, all unified by the unique advantages of hydrogen bonding in the construction of complex molecules from simple precursors.

From the contents:

* Introduction
* Hydrogen Bond Catalysis or Br?nsted Acid Catalysis? General Considerations
* Computational Studies of Organocatalytic Processes Based on Hydrogen Bonding
* Oxyanion holes and their mimics
* Br?nsted Acids, H-Bond Donors, and Combined Acid Systems in Asymmetric Catalysis
* Hydrogen Bonding in Organic Synthesis - (Thio)urea Organocatalysts
* Highlights of Hydrogen Bonding in Total Synthesis

Providing everything you need to know, this is a definite must for every synthetic chemist in academia and industry.

About this edition

• Publisher: Wiley-VCH
• Publication date: 2009
• ISBN 10: 352731895X
• ISBN 13: 9783527318957
• Binding: Hardcover
• Edition number: 1
• Number of pages: 395
• Editor: Pihko Petri M.