Cardiovascular and Metabolic Disease: Scientific Discoveries and New Therapies (Drug Discovery): Volume 45 - Hardcover

Hardcover

ISBN 10: 178262046X ISBN 13: 9781782620464

Publisher: Royal Society of Chemistry, 2015

Synopsis

Cardiovascular and metabolic diseases remain the number one cause of death in developed countries and their prevalence is increasing rapidly in developing nations. This book brings together the recent information on these disorders and the links that exist between them in order to provide a complete picture of drug discovery for these conditions. The main three sections comprehensively discuss obesity, hypertension and cardiovascular disease, and diabetes in turn, following an introduction to the molecular links between them. The final chapter provides perspectives on future directions of the field. Chapters are contributed by leaders in the field from academia and industry and cover biomarkers, risk factors, gene-environment interactions, therapies and the various types of animal models that have been used to study each disease. Case studies describing the implementation of animal models in drug development further enhance the book's usefulness as a comprehensive guide to this important therapeutic area. Providing a full picture of the various types of animal models that have been used to study obesity, hypertension, and insulin resistance with recent case studies, this book provides a valuable resource for medicinal chemists and clinicians working in these disease areas.

About this title

Review:

In summary, this book provides an extremely useful in-depth review and background of cardiovascular and metabolic diseases

--Dr. Alleyn T. Plowright "ChemMedChem "

The book is very biology focused but still provides value for the medicinal chemist and is written in a structured manner that is easy to follow for a broader readership.

--Dr. Alleyn T. Plowright "ChemMedChem "

About this edition

• Publisher: Royal Society of Chemistry
• Publication date: 2015
• ISBN 10: 178262046X
• ISBN 13: 9781782620464
• Binding: Hardcover
• Edition number: 1
• Number of pages: 405
• Editor: Peplow Philip, Adams James, Young Tim