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Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431670432ISBN 13: 9784431670438
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cardiac performance is regulated not only by cardiac muscle properties but also by several other factors, including those associated with the neurohumoral system and the mechanical characteristics of the peripheral circulation. New information con cerning these regulatory factors has furthered our understanding of the pathophysi ology of cardiac dysfunction. However, controversy remains, along with a need to integrate these multidisciplinary findings. It was with this in mind, together with my continuing interest in the response of the normal and diseased heart to variations in loading conditions, that the satellite symposium entitled 'Interactions Between Car diac Function and Vascular Dynamics' was organized and dedicated to my mentor, Dr. T. Takishima. The symposium was held in Fukushima, Japan, in 1992 following the Tenth Inter national Conference of the Cardiovascular Systems Dynamics Society in Kobe, Japan, which was organized by the then president of the society, Dr. Masatsugu Hori. The Fukushima symposium and the Kobe conference were stimulating and informative. To commemorate these events, Dr. Hori, Dr. Janicki, and I decided to publish this book. It covers topics that were presented then as well as pertinent new material. As a result, the book includes not only updated reviews but also up-to-date findings that were not considered at the two scientific sessions. The high level attained in this book is due to the outstanding contributions from internationally renowned scientists. This final product of their efforts should prove to be a valuable source of information to the reader. 420 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431659064ISBN 13: 9784431659068
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Combining harmonic technology and an ultrasound contrast agent, harmonic imaging now plays a vital role in the diagnosis and treatment of hepatic tumors. Contrast harmonic imaging is especially valuable in cases of hepatocellular carcinoma (HCC), the incidence of which has risen dramatically in Europe, North America, and Asia in recent years. Harmonic imaging is bringing about revolutionary changes in the diagnosis and treatment of HCC, and this book provides the most up-to-date information and guidelines for effective use of this superior technique. Generously illustrated with photographs and diagrams, with accompanying text by a leading expert in the field, this acclaimed book is a valuable state-of-the-art resource for clinicians and researchers in radiology and internal medicine, including hepatology and gastroenterology. 288 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431668705ISBN 13: 9784431668701
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Molecular systems are assemblies of molecules designed to possess special qualities and desired functionality. Such systems are important because they provide materials with novel properties, and they will be particularly useful for minimizing electronic devices. Molecular systems often form organized molecular crystals, polymers, or thin films that are significantly more complex than current materials. To provide a sound basis for understanding these levels of complexity, this book provides an analysis of the fundamentals of electronic structures, dynamic processes in condensed phases, and the unique properties of organic molecular solids and the environmental effects on these properties. Also covered are the latest methods in physical chemistry that are particularly useful for deriving and controlling the functionality of molecular systems. A second volume subtitled From Molecular Systems to Molecular Devices is also being published. 352 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431542302ISBN 13: 9784431542308
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This work describes novel, effective hydrogen-bond (HB) donor catalysts based on a known bifunctional tertiary amine-thiourea, a privileged structure, which has been proven to be one of the most widely used organocatalysts. These HB donor catalysts derived from quinazoline and benzothiadiazine were initially synthesized as novel HB donors with their HB-donating abilities being measured by analytical methods. They were found to be effective for a variety of asymmetric transformations including Michael reactions of a, b-unsaturated imides and hydrazination reactions of 1,3-dicarbonyl compounds. Thiourea catalysts that have an additional functional group are also described. Specifically, thioureas that bear a hydroxyl group were synthesized and subsequently used as novel bifunctional organocatalysts for catalytic, asymmetric Petasis-type reactions involving organoboronic acids as nucleophiles. These addition reactions were difficult to achieve using existing organocatalysts. One of the developed catalytic methods can be applied to the synthesis of biologically interesting peptide-derived compounds possessing unnatural vinyl glycine moieties. These findings introduce new criteria required for the development of organocatalysts for asymmetric reactions, thus making a significant contribution to the field of organocatalysis. 124 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431659269ISBN 13: 9784431659266
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Among the topics of interest to organic chemists today are the versatility and uniqueness of electrolysis procedures in organic synthesis, as well as the latest advances in methodology, including basic concepts for the design of electrolysis conditions and apparatus. The International Symposium on Electroorganic Synthesis met in Kurashiki, Japan, in September 1997 for lectures on all aspects of current research in the field. This volume comprising the papers from the symposium consists of two parts. Part I, Electrooxidation, includes papers on alcohols and phenols, olefins and aromatics, halogenation, polymers, and electrodes, among others. Included in Part II, Electroreduction, are papers on carbonyl compounds, halogen-containing compounds, reaction with EG bases, and metal complexes. The novel trends presented here will be of special interest to researchers and graduate students in electroorganic chemistry and are a valuable resource for all organic chemists. 484 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 443154125XISBN 13: 9784431541257
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The environmental field is deep and wide. In the flood of information, how can people understand the underlying causes of what they hear about the environment from newspapers and television This book was originally published in Japanese, with the aim of providing basic information about the ideas and methods to see and understand the interconnection between nature and human activities from a systematic point of view. The author subsequently prepared an English version of the same material for use as a textbook for the Global Environmental Leaders Program at Nagoya University, where he taught many students from Asia and Europe. The book covers diverse environmental issues such as climatic change, biodiversity preservation, energy conservation, and resource recycling. Readers can learn common methods of analysis and thinking to identify the core essence of economic and ecological interdependence, to look at problems from an overarching perspective, and to consider countermeasures to be taken. 164 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431670165ISBN 13: 9784431670162
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Advances in cellular physiology and molecular biology have now disclosed the metabolic changes and adaptational responses of the heart to various kinds of stresses. Topics covered in this volume include the regulation of myocardial proteins in mechanical overload, the alteration of adrenoceptors in the stressed heart, metabolic adaptation in cardiac hypertrophy, intracellular calcium metabolism in the ischemia-reperfused myocardium, calcium overload as a cause of myocardial stunning, acquisition of ischemic tolerance by ischemic preconditioning, factors that accelerate myocardial injury, and ventricular remodeling in the ischemic heart. As an update of the latest findings in basic cardiology, this book will benefit both researchers and clinical practitioners. 408 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431683453ISBN 13: 9784431683452
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since 1998, the Japanese Society of Hepatology has campaigned to fight hepatocellu lar carcinoma (HCC). Because the mortality rate for this disease has reached more than 30 per 100,000 population, the organizing committee chose HCC as the main topic of the 1999 Yamaguchi Symposium on Liver Diseases. Regarding hepatocar cinogenesis, we know that HCC often develops secondary to liver cirrhosis; thus liver cirrhosis must be recognized as a prevalent pathological condition leading to HCC. If we can control liver fibrosis, we can reduce the risk for HCC among patients with chronic hepatitis. To achieve this goal, we must know more about hepatic fibrosis. Professor Michael J. P. Arthur is familiar as a leading scientist in this field. We were fortunate that he accepted our invitation to speak. His lecture titled 'Mechanisms of the Progression and Regression of Liver Fibrosis' provided important advice for developing antifibrotic agents. We also invited Professor Mark A. Zern, who has been studying hepatic fibrosis for some time. In the symposium he talked about novel approaches, including gene therapy, to treat acute and chronic hepatic diseases in the 21st century. In addition to the informative talks by those guests from abroad, the lecture by Dr. J. Fujimoto was very impressive. He revealed that gene therapy using hepatocyte growth factor (HGF) could inhibit progression to liver cirrhosis in rats repeatedly injected with dimethylnitrosamine (DMN). Dr. Fujimoto has already pub lished his finding that administration of HGF reduced hepatocarcinogenesis in rats. 140 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431670076ISBN 13: 9784431670070
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the discovery of superoxide dismutase more than three decades ago, there has been rapid growth in the knowledge of oxidative stress and disease. This volume containing the proceedings of the 13th Yamaguchi Symposium on Liver Disease includes discussion of the direct cellular effects of hepatitis C virus (HCV) proteins on hepatocytes and reviews evidence that oxidative stress caused primarily by the HCV core protein plays a key role in disease pathogenesis. Also included are chapters on new aspects of oxidative stress and liver disease such as carbon monoxide as a regulator of liver microcirculation, hepatic iron accumulation and the incidence of hepatocellular carcinoma, and oxidative stress in the absence of inflammation in hepatocarcinogenesis. This collection of papers from the Yamaguchi Symposium creates a valuable reference resource for physicians and hepatologists. 120 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431670017ISBN 13: 9784431670018
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The meteoric rate at which the human genome is being sequenced has presented to the research community a vast array of newly discovered genes, which in tum has catalyzed an even more dramatic effort to decipher this voluminous data set into understanding how genes function both individually and in complex pathways that regulate the biochemistry of life. A compendium of gene expression data, enhanced by complete proteomic analysis, will enable investigators to probe into the complexities of the mechanisms of normal genetic and metabolic pathways and, subsequently, how disease occurs when they malfunction. The new science of toxicogenomics combines genomic, proteomic, and informatics technologies, and biological research can now foresee a time when there will be a full comprehension of the complex dynamic mechanisms of genetics, biochemistry, and physiology. The inherent power of toxicogenomics derives from an amalgamation of multiple scientific disciplines that were originally drawn together to facilitate sequencing the three billion bases that comprise the human genome. Traditionally, the science of toxicology has been founded upon empirical codification of dose-related effects. It has evolved to studies that are directed towards understanding the mechanisms by which individual agents cause their effects in humans. Due to technical limitations, this process has been relatively slow, since it has accomplished one chemical or one effect at a time. 256 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431670408ISBN 13: 9784431670407
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Until now, the general belief has been that premature baldness (male pattern bald ness: M.P.B., or androgenetie alopeeia) is a hereditary eondition that progresses with age and for which there is no eure. If the father is bald, it is assumed that the ehild may also be destined to be bald sometime in the future. The existing theory throughout the world is that the eentral portion of the hair follicle is the hair root, and hair ean never regrow if the hair root has been removed. Dr. Inaba has introdueed a new theory that the eentral portion of the hair folliele is not only the hair root but the upper isthmal portion elose to the duet opening of the sebaeeous gland. This is a totaUy new understanding of the hair growth mechanism and the hair eyele. In his experienee in the surgieal removal of the sweat glands, whieh also removes the hair root, Dr. Inaba has found inereasing evidenee that hair regrows if the sebaeeous gland is left intaet. 352 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431670343ISBN 13: 9784431670346
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On the threshold of the twenty-first century, the ordinary Japanese citizen has become acutely aware that various environmental hazards pose a serious threat to daily life; such hazards include the problems of waste disposal, dioxin and other substances that disturb humans' endocrine balance. Who, a mere decade ago when these problems were first brought to our attention, would have anticipated that these environmental problems would so quickly become so common and so serious At the same time, environmental problems on a global scale, such as ozone depreciation by chlorofluorocarbons (CFCs), global warming and climate change, have become topics of everyday conversation. The main objective of this book is to take in these environmental problems, focus ing on the two locally important and interrelated issues of waste and pollution. This will enable us to investigate the whole range of problems, from regionally based pol lution caused by waste disposal and dioxin to the transboundary warming brought about by CO and CFCs. We shall thus be able to analyze comprehensively the whole 2 extent of 'waste and pollution' problems, ranging from those caused by real garbage and domestic waste to the many kinds of technologically generated waste that result from the production, circulation, and consumption of industrial goods and services. 196 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431540830ISBN 13: 9784431540830
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A lot of economic problems can be formulated as constrained optimizations and equilibration of their solutions. Various mathematical theories have been supplying economists with indispensable machineries for these problems arising in economic theory. Conversely, mathematicians have been stimulated by various mathematical difficulties raised by economic theories. The series is designed to bring together those mathematicians who are seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking effective mathematical tools for their research. 240 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431542000ISBN 13: 9784431542001
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis presents a systematic study of the orbital evolution, gravitational wave radiation, and merger remnant of the black hole-neutron star binary merger in full general relativity for the first time. Numerical-relativity simulations are performed using an adaptive mesh refinement code, SimulAtor for Compact objects in Relativistic Astrophysics (SACRA), which adopts a wide variety of zero-temperature equations of state for the neutron star matter. Gravitational waves provide us with quantitative information on the neutron star compactness and equation of state via the cutoff frequency in the spectra, if tidal disruption of the neutron star occurs before the binary merges. The cutoff frequency will be observed by next-generation laser interferometric ground-based gravitational wave detectors, such as Advanced LIGO, Advanced VIRGO, and KAGRA. The author has also determined that the mass of remnant disks are sufficient for the remnant black hole accretion disk to become a progenitor of short-hard gamma ray bursts accompanied by tidal disruptions and suggests that overspinning black holes may not be formed after the merger of even an extremely spinning black hole and an irrotational neutron star. 192 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431542183ISBN 13: 9784431542186
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis presents a study of the origin of an apparently extended X-ray emission associated with the Galactic ridge. The study was carried out with broadband spectra obtained from mapping observations in the Galactic bulge region conducted in 2005-2010 by the Suzaku space X-ray observatory. The spectra were analyzed with a newly constructed X-ray spectral model of an accreting white dwarf binary that is one of the proposed candidate stars for the origin of the Galactic ridge emission in the higher energy band. Fitting of the observed Galactic ridge spectra with the model showed that there is another spectral component that fills the gap between the observed X-ray flux and the component expected from the accreting white dwarf spectral model in the lower energy band. This additional soft spectral component was nicely explained by an X-ray spectral model of normal stars. The result, together with previously reported high-resolution imaging results, strongly supports the idea that the Galactic ridge X-ray emission is an assembly of dim, discrete X-ray point sources. 172 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431542361ISBN 13: 9784431542360
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is the first of its kind to deal with fabrication processes of metal matrix composites (MMCs) theoretically, experimentally, systematically, and instructively. The theoretical bases of fabrication processes and recycling processes of MMCs are established in this volume. Most other books in the field are concerned with the mechanics of properties, which is not easy for readers to grasp, and they introduce fabrication processes only as techniques without theoretical discussion. Because this book provides a clear image of the fabrication processes of MMCs without using complicated mathematics, readers can use production theory to create new composites. Also, fundamental concepts of recycling of MMCs are given in this book for the first time so as to meet the demands for solving environmental problems. This work originally was published in Japanese and has attained a high reputation among Japanese professors and researchers in the field. 216 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431543112ISBN 13: 9784431543114
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The properties and nature of water clusters studied with novel spectroscopic approaches are presented in this thesis. Following a general introduction on the chemistry of water and water clusters, detailed descriptions of the experiments and analyses are given. All the experimental results, including first size-selective spectra of large clusters consisting of 200 water molecules, are presented with corresponding analyses. Hitherto unidentified hydrogen bond network structures, dynamics, and reactivity of various water clusters have been characterized at the molecular level. The main targets of this book are physical chemists and chemical physicists who are interested in water chemistry or cluster chemistry. 192 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431540822ISBN 13: 9784431540823
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For the first time in human history, more than half the world's population is urban. A fundamental aspect of this transformation has been the emergence of giant cities, or megacities, that present major new challenges. This book examines how issues of megacity development, urban form, sustainability, and unsustainability are conceived, how governance processes are influenced by these ideas, and how these processes have in turn influenced outcomes on the ground, in some cases in transformative ways. Through 15 in-depth case studies by prominent researchers from around the world, this book examines the major challenges facing megacities today. The studies are organized around a shared set of concerns and questions about issues of sustainability, land development, urban governance, and urban form. Some of the main questions addressed are: What are the most pressing issues of sustainability and urban form in each megacity How are major issues of sustainability understood and framed by policymakers Is urban form considered a significant component of sustainability issues in public debates and public policy Who are the key actors framing urban sustainability challenges and shaping urban change How is unsustainability, risk, or disaster imagined, and how are those concerns reflected in policy approaches What has been achieved so far, and what challenges remain The publication of this book is a step toward answering these and other crucial questions. 432 pp. Englisch.
Published by Springer Japan Jan 2013, 2013
ISBN 10: 4431541438ISBN 13: 9784431541431
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Advances in CT have enabled us to detect small lung cancers, which has changed the lung cancer surgery from lobectomy to a lesser lobar resection such as a segmentectomy or wedge resection. While wedge resection is a simple procedure, it has a higher risk of local recurrence of cancer than a lobectomy. On the other hand, segmentectomy is a well known curative surgery for small lung cancers. However, it is difficult to perform accurately because of its anatomical complexity, which makes surgeons hesitant to use it. The book 'Illustrated Anatomical Segmentectomy for Lung Cancer' provides readers a detailed explanation of segmentectomy with numerous easy-to-understand color illustrations showing the precise segmental anatomies for each pattern of the procedure. To better illustrate an accurate anatomical segmentectomy, the text shows details of anatomy during segmentectomy. This can involve up to 25 patterns, each of which is shown in roughly 10 illustrations. 264 pp. Englisch.