springer basel feb 2014 (4 results)

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is concerned with cardinal number valued functions defined for any Boolean algebra. Examples of such functions are independence, which assigns to each Boolean algebra the supremum of the cardinalities of its free subalgebras, and cellularity, which gives the supremum of cardinalities of sets of pairwise disjoint elements. Twenty-one such functions are studied in detail, and many more in passing. The questions considered are the behaviour of these functions under algebraic operations such as products, free products, ultraproducts, and their relationships to one another.Assuming familiarity with only the basics of Boolean algebras and set theory, through simple infinite combinatorics and forcing, the book reviews current knowledge about these functions, giving complete proofs for most facts. A special feature of the book is the attention given to open problems, of which 185 are formulated.Based on Cardinal Functions on Boolean Algebras (1990) and Cardinal Invariants on Boolean Algebras (1996) by the same author, the present work is much larger than either of these. It contains solutions to many of the open problems of the earlier volumes. Among the new topics are continuum cardinals on Boolean algebras, with a lengthy treatment of the reaping number. Diagrams at the end of the book summarize the relationships between the functions for many important classes of Boolean algebras, including interval algebras, tree algebras and superatomic algebras. 584 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This special volume focuses on optimization and control of processes governed by partial differential equations. The contributors are mostly participants of the DFG-priority program 1253: Optimization with PDE-constraints which is active since 2006. The book is organized in sections which cover almost the entire spectrum of modern research in this emerging field. Indeed, even though the field of optimal control and optimization for PDE-constrained problems has undergone a dramatic increase of interest during the last four decades, a full theory for nonlinear problems is still lacking. The contributions of this volume, some of which have the character of survey articles, therefore, aim at creating and developing further new ideas for optimization, control and corresponding numerical simulations of systems of possibly coupled nonlinear partial differential equations. The research conducted within this unique network of groups in more than fifteen German universities focuses on novel methods of optimization, control and identification for problems in infinite-dimensional spaces, shape and topology problems, model reduction and adaptivity, discretization concepts and important applications. Besides the theoretical interest, the most prominent question is about the effectiveness of model-based numerical optimization methods for PDEs versus a black-box approach that uses existing codes, often heuristic-based, for optimization. 636 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail. 328 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Granulocyte colony-stimulating factor (G-CSF or GCSF) is a secreted glycoprotein that stimulates the proliferation and differentiation of granulocyte precursor cells, and induces mobilization of peripheral blood progenitor cells from the bone marrow. Development of recombinant human G-CSF has had a profound impact on the treatment of many diseases, including severe chronic neutropenia and cancer, and has enabled peripheral stem cell transplantation to supplant bone marrow transplantation in the autologous setting. This Milestones in Drug Therapy volume describes the experience of the last 20 years of treatment with recombinant human G-CSF, including the basic science, the use of recombinant human G-CSF in both the oncology and nononcology settings, and the safety and economics of its use. Many of the authors were the original investigators of recombinant human G-CSF and other authors are key researchers who provide their outlook for the next 20 years for use of and research with recombinant human G-CSF. 500 pp. Englisch.