humana press nov 2012 (40 results)

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Sir Richard Doll, FRS, FRCP ICRF Cancer Research Studies Unit Radcliffe Infirmary, Oxford, UK The twentieth century has seen few changes more remarkable than the improvement in health that has occurred nearly everywhere, most spectacularly in the economically developed countries. In these countries improved nutrition, better housing, the control ofinfection, smaller family sizes, and higher standards of education have brought about a situation in which more than 97% of all liveborn children can expect to survive the first half ofthe three score years and ten that formerly was regarded as the allotted span oflife. From then on, however, the position is less satisfactory. Some improvement has occurred; but the proportion of survivors who die prematurely, that is under 70 years of age, varies from 25% to over 50% in men and from 13% to 28% in women, the extremes in both sexes being recorded, respectively, in Japan and Hungary. Most of these deaths under 70 years of age must now be called premature, even in Japan. For most of them are not the result of any inevitable aging process, but instead are the consequences of diseases (or types of trauma) that have lower-often much lower-age-specific incidence rates in many of the least developed countries. 480 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -153 posters. While plant biotechnology for enzyme production and designer biomass merged as 'hot topics' throughout the Symposium, the preface for each session is included in the introductions. Special topic discussions were led on 'Brazilian Bioethanol Progress' by Gisella Zanin, State University of Maringa, Brazil, and on 'Nontradi tional Bioprocessing' by Gene Petersen, National Renewable Energy Labo ratory, Golden, CO. A tour of the Colorado Bioprocessing Center, a 'state of the art' con tract research facility at Colorado State University highlighted the process development and scale-up activities ongoing with several industrial clients. The 1999 Charles D. Scott Award for Distinguished Contributions in the field of Biotechnology for Fuels and Chemicals was presented to Dr. Charles E. Wyman, Dartmouth College professor, Thayer School of Engineering, Hanover, New Hampshire. This award is named in honor of Dr. Charles D. Scott, the founder of this Symposium and its chair for the first ten years. 1212 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book's contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice. Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications. 360 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the past decades, knowledge about the cellular and molecular basis underlying the visual process has remarkably increased. In Retinal Degeneration: Methods and Protocols, expert researchers in the field provide a guide of relevant and state-of-the-art methods for studying retinal homeostasis and disease. These include methods and techniques for addressing cell culture systems and animal models of disease, their generation, their phenotypic and molecular characterization as well as their use in therapeutic approaches to the retina. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Retinal Degeneration: Methods and Protocols aids scientists in continuing to study the cutting-edge techniques of retinal cell biology in health and disease. 400 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cotton is the most important textile and cash crop and is widely cultivated in more than 70 countries, including the United States, China, and India. Because its long life cycle and complicated genetic background, it is hard to improve cotton using traditional breeding techniques although it has made much progress in the last several decades. Currently, transgenic techniques have become a powerful tool to improve cotton and transgenic cotton is among the first commercially genetically modified crops. Transgenic Cotton: Methods and Protocols provides a comprehensive collection of methods for creating and monitoring transgenic cotton and its application on agricultural and basic research. Divided into five convenient sections, topics covered include the current status and perspectives of transgenic cotton, the principle and methods for making transgenic cotton, the methods for detecting foreign gene copy and expression in transgenic plants, the improvement of cotton using transgenic technology, and finally the methods for monitoring the potential impact of transgenic cotton on environment, including gene flow. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Transgenic Cotton: Methods and Protocols will serve as an excellent resource for scientists as well as graduate students who work on transgenic plants, plant genetics, molecular biology and agricultural sciences. 288 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The post-genomic revolution is witnessing the generation of petabytes of data annually, with deep implications ranging across evolutionary theory, developmental biology, agriculture, and disease processes. Data Mining for Systems Biology: Methods and Protocols, surveys and demonstrates the science and technology of converting an unprecedented data deluge to new knowledge and biological insight. The volume is organized around two overlapping themes, network inference and functional inference. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Data Mining for Systems Biology: Methods and Protocols also seeks to aid researchers in the further development of databases, mining and visualization systems that are central to the paradigm altering discoveries being made with increasing frequency. 292 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mammalian oocytes occupy a critical nexus in reproduction as they not only contribute half the genetic makeup of the embryo but also provide virtually all of the cytoplasmic building blocks required for sustaining embryogenesis. The journey that transforms a primordial germ cell into a mature oocyte (or egg) capable of fertilisation and embryonic development is of unrivalled complexity. The end-product of this remarkable developmental process is the 'mature' egg, now replete with macromolecules and organelles, and poised to support embryonic development if fertilisation should occur. Given the importance of the oocyte for embryonic development, it is of no surprise that the oocyte holds centre stage in fertility clinics and greatly influences the outcome of assisted reproductive treatments (ARTs). Mammalian Oocyte Regulation: Methods and Protocols provides a highly diverse compendium of detailed methodologies - primarily focusing on the murine model but also including chapters on human oocytes - for enabling researchers to interrogate every aspect of mammalian oocyte development including recombination, meiotic maturation, oocyte substrate uptake, chromosomal segregation and fertilisation. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Mammalian Oocyte Regulation: Methods and Protocols serves as an ideal guide to novice oocyte researchers, experts who wish to add another dimension to their established portfolio, as well as the wider research community. 324 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -G. Blasius ftrSt described the anatomic aspects of spinal cord injury (SCI) in 1666. Until thattime, society had totally ignored the physically disabled, let alone allowed them to mingle socially and sexually. ThemilitaIymortalityratebetween 1814-1914wasestimatedto be50-80%,although sexualandsocioculturalimplicationswere not addressed. Ina1928novel, Lady Chatterley's Lover, D.H.Lawrence stronglyreflected the sexual concernsofa paraplegic who had been labeled impotent The modern managementofSCI was initiated by Monroe and Guttman in 1943, but with heavy emphasis on physical and urological rehabilitation and only supetficial attention to sexual dysfunctions. H. W. Home et al. started the investigation of SCI infertilityproblems in1950. Itwasnotuntil1960thatBorsandComarr collaboratedonastudythatclassifiedthetypesofsexualdysfunctions inrelation toneurologicallevelsoflesionsfollowing spinalcooltrauma. Nonnal (nondisabled)sexualitycameofageduring thepasttwo decades.Thiswashighlightedbythe 1966publicationofW.Masters', HumanSexualResponse. However,thetopicofsexualityinphysically challenged(handicapped)personsremainslargelytabooinourpresent society. Thereareanestimated10-12millionSCIpersonsworldwide. InAmerica,thereareapproximately1.2-1.5millionSCIvictims,with an annual incidenceof12,000-15,000,oroneevery 35minutes. The visibility of SCI persons was enhanced when the United Nations declared 1980-1990as thedecadeofdisabledpersons. Furthennore, theenactmentintolaw,inJuly, 1990,ofthe AmericanDisabilities Act, pointed out the handicapped person's right to the fullest pursuit of happiness. Since the release in 1974of K. Heslinga's Not Made of v vi Preface Stone, only a handful ofbooks on medical sexuality for the disabled have been published. This book has three majorobjectives: 1. toprovidethoroughandcomprehensivecoverageofdisabled persons' sexuality in all sexual orientations; 2. to introduce new tenninologies and theories, to redefine certainsexualdysfunctions,and todescribeupdatedtreatment formats; and 3. topresentresearchandinnovationsthatmaystimulatefurther investigationsintodisabled sexualityduring the nextdecade. The first partofthis bookdefines new sexual terminology and describes the full spectrumofsa sexual challenges. Thesecondhalfofthebookdealswithavarietyofdiagnosticand therapeutic sexual innovations, AIDS implications, and cosmic sex ology. Finally, the Appendix lists international sexual referral centers and informationorganizations. 576 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Acute and chronic viral hepatitis infections are serious public health threats around the world. The different infections have different epidemiology and natural his- ries, and children play important roles in each of these. For example, children are important reservoirs for acute hepatitis A, childhood infections are responsible for most of the global morbidity associated with chronic hepatitis B, and perinatal transmission of hepatitis C continues to occur, even as the overall incidence of new infections wanes. Some non-A through E viral hepatitis infections are seen p- dominantly in infants and young children, while others have specific implications for this population. Therapeutic options for children with chronic viral hepatitis are limited when compared to those available for adults, especially for hepatitis B, and considerations given to long-term therapy have dramatic implications when dealing with the long life expectancy of these young patients. With these issues in mind, this unique volume has been created to address the special considerations regarding viral hepatitis in children. It includes the latest information and recommendations specifically directed at the pediatric population, and highlights the knowledge gaps which will need to be filled to improve our understanding of these infections and treatment of this special group. Experienced practitioners from around the world have contributed these reviews, incorporating the latest studies, the current recommendations, and the distinctive pediatric issues that shape clinical care, and will determine the research agenda for this field going forward. 184 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cyberforensics is a fairly new word in the technology our industry, but one that n- ertheless has immediately recognizable meaning. Although the word forensics may have its origins in formal debates using evidence, it is now most closely associated with investigation into evidence of crime. As the word cyber has become synonymous with the use of electronic technology, the word cyberforensics bears no mystery. It immediately conveys a serious and concentrated endeavor to identify the evidence of crimes or other attacks committed in cyberspace. Nevertheless, the full implications of the word are less well understood. Cyberforensic activities remain a mystery to most people, even those fully immersed in the design and operation of cyber te- nology. This book sheds light on those activities in a way that is comprehensible not only to technology professionals but also to the technology hobbyist and those simply curious about the eld. When I started contributing to the eld of cybersecurity, it was an obscure eld, rarely mentioned in the mainstream media. According to the FBI, by 2009 organized crime syndicates were making more money via cybercrime than in drug traf - ing. In spite of the rise in cybercrime and the advance of sophisticated threat actors online, the cyber security profession continues to lag behind in its ability to inves- gate cybercrime and understand the root causes of cyber attacks. In the late 1990s I worked to respond to sophisticated attacks as part of the U. S. 184 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Conference Overview and the Role of Chemistry in High-Temperature Materials Science and Technology LEO BREWER Department of ChemistIy, University of California, and Materials and Chemical Sciences Division, Lawrence Berkeley Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 I don't want to compete with the fascinating historic account that John Drowart gave us, but I would like to go through the history of high don't get the reaction that I get from temperature symposia. I hope I some of my classes when I say, 'Remember when such-and-such hap pened during the War ' And I get this blank look, and one of the students will say, 'I wasn't born until after the Korean War. ' Neverthe less, during World War II, many people in the high-temperature field had their first initiation. But there was one handicap. Owing to security measures, they were not able to interact with one another. Following the War, it was recognized that the high-temperature field was going to expand to meet the demands for materials with unique properties. To meet the demands for new fabrication techniques, it was important to establish better communications among various people. High-tempera ture symposia were established at that time and have continued very frequently, and I'd like to point out why they are especially important for this field. One problem is that it is not easy to work at high temperatures. 476 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Activation, inhibition, or destruction of the nervous system or its component parts as a vital tool for the investigation of function has undergone remarkable development; indeed, new approaches have been developed that allow for these actions to be used as therapeutic tools. In Stimulation and Inhibition of Neurons, experts in the field provide an overview of modern methods for generating lesions as well as for stimulating and inhibiting neural pathways. Many new techniques such as optogenetics and the use of the in situ perfused preparation are examined, while, in other sections, the use and validity of more well-known approaches are reassessed. Written for the Neuromethods series, chapters examine their respective topics thoroughly and include the kind of detail and implementation advice that ensures successful results in the laboratory. Authoritative and cutting-edge, Stimulation and Inhibition of Neurons serves as an ideal guide for researchers seeking to gain further knowledge of the complex functions of the brain. 332 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -ADHD in Adults: A Practical Guide to Evaluation and Management is the product of a unique collaboration of international specialists. This volume offers easy-to-read guidance, and includes checklists, rating scales and treatment planning tools. It was designed for a broad audience of caregivers working in diverse settings, including psychiatrists, social workers, primary care physicians, nurse specialists and psychologists. The authors are highly acclaimed clinicians, investigators and educators. They offer step-by-step guidance for implementation of best practices, drawing from clinical research and their experience treating thousands of patients. They cover diagnosis, treatment planning, and state-of-the-art application of pharmacology, psychotherapy, skill-building, family system and environmental interventions - for both simple and complex cases. The scales and worksheets in this Guide were developed to efficiently facilitate assessment and management. The Editor is an international leader in the field from the Clinical and Research Program in Adult ADHD at Massachusetts General Hospital (MGH) and Harvard Medical School, which has made pioneering and highly cited contributions to the understanding of ADHD. This Guide is a definitive, indispensable resource for all health providers who wish to optimize their approach to adult patients with ADHD. 244 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the explosion of research on genes capable of causing cancer, it has become clear that mutations in the GTPase, Ras, a major regulator of cell division, are found in about 30% of all human cancers, and that farnesylation, a lipid posttranslational modification of Ras, is required for its cancer-causing activity. In Farnesyltransferase Inhibitors in Cancer Therapy, cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farnesyltransferase inhibitors (FTIs) and geranylgeranyltransferase inhibitors (GGTIs) that can be used as anticancer drugs and in cardiovascular and parasitic therapy. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. The book also discusses the results from several phase I and II human clinical trials using a variety of FTIs, and demonstrates the design of hypothesis-driven clinical trials with proof-of-concept using biochemical endpoints.Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific and medical aspects of farnesyltransferase inhibitors. 296 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This Methods in Molecular Biology(TM) series book presents methods specifically adapted and developed for the study of distinct features of L. pneumophila. Includes materials lists, reproducible protocols, and notes on troubleshooting and pitfalls. 652 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity. It has now become a topical subject due to advances in clinical imaging (echo, magnetic resonance, computed tomography) as well as innovation in technologies of in-vivo diagnosis. Cardiac Tumor Pathology presents a spectacular example of these advances with clinico-pathologic correlations. This timely volume covers history, epidemiology, demographics, clinical diagnosis, pathology, imaging by echo, CT and MRI of both benign and malignant cardiac tumors, either primary or secondary. Chemotherapy of malignant neoplasms is also addressed. Special emphasis is given to clinico-pathologic correlations. With all chapters written by experts in their fields, this volume will serve as a useful resource for physicians dealing with, and interested in, this special branch of cardiac oncology and will represent a useful guide for pathologists, clinicians, cardiologists, cardiac surgeons, and radiologists as well as for postgraduate students training in these areas. 212 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The second edition of p53 Protocols expands upon the first edition with progress in p53 research since the publication of the first edition. In p53 Protocols, Second Edition expert researchers in the field detail many of the methods that address the challenging questions of the p53 field. These methods include the identification of the target genes and binding partners of gain of function p53 mutants, methods to determine stress response, autophagy or senescence induced by p53, cell cycle analysis, analysis of different phases of DNA replication modified by p53, and generation of pluripotent stem cells. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, p53 Protocols, Second Edition seeks to aid scientists in the further study into p53 and other tumor suppressors. 248 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells. This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies. 356 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the completion of a finished rice genome sequence, increasing efforts have focused on functional characterization of rice genes, elucidation of the underlying mechanisms involved in major agronomic traits (e.g., high yield, grain quality, abiotic stress tolerance, and disease resistance), and the subsequent translation of genomic knowledge into agricultural productivity via molecular breeding and improved cultural practice. To meet increasing interest in this field, Rice Protocols has been compiled to provide a series of core techniques and approaches commonly used in studying rice molecular biology and functional genomics. These approaches include genetic and molecular techniques such as artificial hybridization, fluorescence in situ hybridization, generation and characterization of chemical and T-DNA insertional mutants, quantitative trait loci (QTLs) analysis and map-based cloning, site-specific transgene integration, and artificial microRNA-mediated gene silencing, along with a variety of 'omics' techniques. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Rice Protocols will prove useful for both beginners and experienced researchers whether they are molecular biologists who want to study rice plants or rice researchers who are interested in learning molecular techniques. 348 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of the book will serve as a source of basic information about testosterone replacement and as a source of reasoned analysis of the controversies surrounding testosterone replacement in the aging male. Physicians and physician extenders will be able to apply evidence management principles to the evaluation and treatment of men with testosterone deficiency; supported by the most recent practice guidelines available. The authors represent a select group of physicians with expertise in androgen deficiency and replacement. Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies will be of great value to all physicians and physician extenders who deliver health care to men of all ages. 164 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Based on the highly successful first edition of Prostate Biopsy: Indications, Techniques, and Complications, this new volume presents new concepts that have emerged in answer to current questions from its audience. Many new perspectives and technologies are presented, many from the authors' internationally recognized work on the topic. Substantial developments in techniques and complications are explored in detail. The chapter authors comprise a complete spectrum of specialists in their respective subject areas. All authors are internationally accepted as the premier authorities on their chosen topics. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond presents new data on the controversial issue of PSA screening and thresholds as indication to perform biopsy. Office based transrectal saturation biopsy is covered in detail. Other topics explored include template guided biopsy and image-guided biopsy as well as a completely new paradigm for prevention of complications.Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond will be of great value and utility to all practicing urologists. 400 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Carotenoids and Human Health provides an introduction to food sources and metabolism. Written by experts in their fields and including the most up-to-date information, this volume serves as an in-depth guide to studies that have been performed in humans and observations that have been made in population level assessments. Special emphasis is given to associations with disease, as well as the importance of carotenoids internationally, specifically as a source of vitamin A for the world. Comprehensive and easy to use, Carotenoids and Human Health is a very useful resource for nutritionists, registered dieticians, medical students, and graduate students. 356 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -active industrial participation in the organizing committee. Recently, the conference has begun a regular informal industrial roundtable (Session 4). This has become very popular as it allows industrial participants to speak more openly. For a broader perspective, R. James Woolsey, Former Direc tor of Central Intelligence Agency, gave an after-dinner address on 'Wagon Trains for the 21st Century: The Role for Biorefineries. ' He urged the attendees of the importance of their efforts to develop renewable, benign processes for the United States and the world based on both security and prosperity reasons. These related to energy supply, support of domestic agriculture, global warming, and other issues. With the Twentieth Symposium, we continued the tradition of pro viding an informal, congenial atmosphere that our participants find condu cive to pursuing technical discussion of program topics. The technical program consisted of 35 oral presentations, a roundtable forum, two spe cial topic discussions, and a poster session of 133 posters. This year, tech nical topics included: Session 1: Feedstocks: New Supplies and Processing Session 2: Applied Biological Research Session 3: Bioprocessing Research Session 4: Emerging Opportunities for Industrial Chemicals Session 5: Bioprocess Evaluation and Confirmation Session 6: Enzymatic Processes and Enzyme Production Special topic discussions were held on 'Defining the Future Separa tions Needs Derived from Bioprocessing' by Earl Beaver, Monsanto Com pany, St. 920 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis. Animal Models of Brain Tumors brings together developments and discoveries in 'in vivo' experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors, therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism. Written for the popular Neuromethods series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results. Authoritative and cutting-edge, Animal Models of Brain Tumors provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments. 408 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -MARK FINKELSTEIN National Renewable Energy Laboratory BRIAN H. DAVISON Oak Ridge National Laboratory The proceedings of the 19th symposium on Biotechnologyfor Fuels and Chemicals, held in Colorado Springs, Colorado, May 4-8, 1997, had over 200 attendees. This meeting continues to provide a unique forum for the presentation of new applications and recent research advances in the production of fuels and chemicals through biotech nology. The utilization of renewable resources, and in particular cellulosic biomass, has broad implications in today's world of green house gases, global warming, ozone layers, climate change, energy sustainability, and carbon emissions. It also has relevance to the chemical industry's continuing need to both lower current chemi cal production costs and produce novel chemicals. Biotechnology and bioprocessing are now making it possible to convert this bio mass to fuels and chemicals in a commercially attractive fashion. The 19th Symposium captures a wide range of technical topics from an academic, industrial, or government perspective. A vari ety of biomass feedstocks are discussed in Session 1, along with several updated and innovative pretreatment processing approaches. The ability to turn lignocellulosic materials into simple sugars offers great opportunities to generate cost-effective feed stocks to be used in biotechnological processes for the production of fuels and chemicals. Through the advent of genetic engineering, the development of a series of exciting new biocatalysts and microbes were presented in Session 2. 1052 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the Seventeenth Symposium on Biotechnology for Fuels and Chemicals, leading researchers from academia, industry, and government present state-of-the-art papers on how bioengineering can be used to produce fuels and chemicals competitively. This year's program covered topics in thermal, chemical, and biological processing; applied biological processing; bioprocessing research; process economics and commercialization; and environmental biotechnology. The ideas and techniques described will play an important role in developing new biological processes for producing fuels and chemicals on a large scale, and in reducing pollution, waste disposal problems, and the potential for global climate change. 1064 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer encesheldbytheInternationalAtomicEnergyAgency. Thefirsttook placeinAmsterdamin 1967,thesecondin Bledin 1972,andthethird inViennain 1978. Theaimoftheseconferenceshasbeentostimulate discussions between scientists who are working as biologists, envi ronmentalists, and physicians, and those who are working on the advancementofnuclear analytical techniques. The 1989 Conference was held at the National Institute of Standards and Technology (NIST, formerly the National Bureau of Standards)inGaithersburg,Maryland. ThefocalpointoftheConfer ence was the presentation of results from multidisciplinary research involvingnuclear analytical techniques and their applications to the life sciences. Wehave obtained contributions from life sciencefields thatrelatethenuclear analyticalmethods to abroad scopeofbiologi cal, medical,and environmental applications. Deliberately,our defi nition of nuclear analytical techniques was made flexible. Methods and applications were treated in a more comprehensive way than thoseatestablished meetings. Particularconsideration was given to contributions from developing countries. We are indebted to many people and organizations for their assistancein making this symposium possible. TheConference was organizedbytheUSDepartmentofCommerce'sNISTincooperation with the International Atomic Energy Agency, by supplying both financial support and scientific expertise. The meeting was cospon soredbytheAmericanNuclearSociety,theUSDepartmentofEnergy, andtheFoodandDrugAdministration,whoprovidedbothorganiza tional and financial support. We hope that the results of this Conference, presented here, will stimulatethe developmentofnew collaborativeresearch efforts betweenthe life sciencesand analytical fields. Acontinuationofthis series ofconferences willbe a measureofthe successofthis interdis ciplinary collaboration. 808 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Epstein-Barr virus (EBV), isolated in 1966, continues to draw worldwide attention as an important human pathogen. Its impor tance is largely related to the continuing accumulation of evidence that implicates EBV as an etiological factor for certain types of human cancer. More recent investigations on this virus have focused on the identity of the viral genes responsible for the different disease mani festations observed following viral infection. It is hoped that by thorough investigation of this virus, clues to how cancer develops from a normal cell will surface. In addition, many of the gene products are now being exploited for the development of new and more sensitive tests for the diagnosis and clinical management of individu als with EBV -associated diseases. Thus, studies on this virus continue to provide new information of importance to our understanding of the malignant process. In an effort to attract both basic and clinical scientists to the same meeting for purposes of scientific exchange and fostering a closer interaction between these individuals, a series of international symposia was initiated in 1984. The first meeting was held in Loutraki, Greece, and was attended by approximately 100 participants. The second international symposium was held in St. Petersburg, Florida, in 1986, and was attended by approximately twice as many partici pants as attended the Loutraki meeting. 504 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research. 572 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Teratology is the study of chemical-induced birth defects. This book is a comprehensive guide to the procedures and methods commonly employed in the safety testing of all classes of chemical for teratogenicity (also referred to as embryotoxicity, developmental toxicity or prenatal toxicity). The various international regulatory requirements are explained in detail, in order that the reader may perform all of the necessary studies for the successful registration or marketing authorisation of a new pharmaceutical, industrial chemical, crop protection product or food additive. Written in the highly successful Methods in Molecular Biology(TM) series format, each chapter gives clear complete instructions on how to perform the task in hand. The authors are respected experts in their field, all with hands-on experience of the procedures described. Teratogenicity Testing: Methods and Protocols gives crucial guidance and tips on how to deal with unexpected results and overcome regulatory difficulties. 616 pp. Englisch.