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Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by LAP Lambert Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by LAP Lambert Academic Publishing 2012-11, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: Chiron Media, Wallingford, United Kingdom
Book
PF. Condition: New.
Published by LAP Lambert Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Human epidermal receptor (HER) 1 inhibitors and HER 1/2 inhibitors have shown benefit against a wide range of solid tumors. However, their use is associated with skin rash in 40-90% of patients, which impacts quality of life and interrupts antineoplastic therapy. The pathologic characteristics of affected skin remain unclear, precluding development of rational therapies. The aim of this study is to evaluate differences in histologic and immunohistochemical (IHC) alterations in rash caused by lapatinib, a dual HER1/2 inhibitor (HER1/2i), and the single HER1 inhibitors (HER1i) cetuximab, erlotinib, and panitumumab. We found a lower inhibition of epidermal kinetics and decreased inflammation in HER1/2i-induced rash. These findings underscore differences in skin toxicity as related to specificity of HER blockade, concordant with clinical tolerability and decreased severity of skin toxicity seen with the HER1/2i lapatinib compared to the HER1 inhibitors cetuximab, erlotinib and panitumumab. 96 pp. Englisch.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
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PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Book Print on Demand
PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by LAP Lambert Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book Print on Demand
Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Human epidermal receptor (HER) 1 inhibitors and HER 1/2 inhibitors have shown benefit against a wide range of solid tumors. However, their use is associated with skin rash in 40-90% of patients, which impacts quality of life and interrupts antineoplastic therapy. The pathologic characteristics of affected skin remain unclear, precluding development of rational therapies. The aim of this study is to evaluate differences in histologic and immunohistochemical (IHC) alterations in rash caused by lapatinib, a dual HER1/2 inhibitor (HER1/2i), and the single HER1 inhibitors (HER1i) cetuximab, erlotinib, and panitumumab. We found a lower inhibition of epidermal kinetics and decreased inflammation in HER1/2i-induced rash. These findings underscore differences in skin toxicity as related to specificity of HER blockade, concordant with clinical tolerability and decreased severity of skin toxicity seen with the HER1/2i lapatinib compared to the HER1 inhibitors cetuximab, erlotinib and panitumumab.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: moluna, Greven, Germany
Book Print on Demand
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Nardone BeatriceShe received her MD from University of Catania (Italy), where she completed her Dermatology residency and earned her PhD in Preclinical and Clinical Pharmacology. She spent 2 years as PhD student at Northwestern Unive.
Published by LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3659297585ISBN 13: 9783659297588
Seller: dsmbooks, Liverpool, United Kingdom
Book
Paperback. Condition: Like New. Like New. Ships from multiple Locations. book.