"SOME ORIGINAL INVESTIGATIONS, SHOWING THE ANTAGONISM BETWEEN MORPHINE AND COCAINE" by Joseph William Stickler, M.S., M.D. [Contained in]: TRANSACTIONS OF THE MEDICAL SOCIETY OF NEW JERSEY, 1895.

Stickler, Dr. Joseph William (1854-1899).

Published by Newark, N.J.: L.J. Hardhan, Printer, 1895., 1895

About this Item

- Octavo, 9-1/2 inches high by 6 inches wide. Dark green cloth titled in gilt on the spine with decorations in blind on the covers. The covers are rubbed and lightly stained. 272 & [1] pages. The endpapers are foxed. Very good. Dr. Joseph William Stickler's 23 page essay "Some Original Investigations, Showing the Antagonism between Morphine and Cocaine" [pages 97 through 119] shows that morphine and cocaine are antagonistic to each other when administered to pigeons and that antropine offers no protection against the prompt and violent action of cocaine. In dogs, four grains of morphine appear to serve as an antidote to four grains of cocaine. Dr. Stickler's investigation into these antagonistic reactions of the two drugs leads him to base his treatment of opium poisoning in humans by administering one-fourth to one-half of a grain of cocaine, to be repeated in 20 minutes if there is no improvement and supplement the dose with coffee as a heart stimulant.Joseph William Stickler, M.S, M.D. (1854-1899) was born in Hoboken, New Jersey. He matriculated in the College of Physicians and Surgeons of New York in 1876 and received his medical degree in 1879. In 1881 he located in Orange, New Jersey and from 1893 to 1899 was visiting surgeon and pathologist to the Orange Memorial Hospital. In the 1880's he had become convinced that bovine foot and mouth disease and childhood scarlet fever were related in their causation. He administered an experimental vaccine to approximately 30 children, and he went so far as to experiment on children by transmitting scarlet fever to them through injection. The results of his experiments, unsuccessful as they were, were published in the leading medical journals of the day. It may be that his obsession to find a cure for scarlet fever and his failure to do so led to his untimely suicide in 1899. Seller Inventory # 96767

Bibliographic Details

Title: "SOME ORIGINAL INVESTIGATIONS, SHOWING THE ...

Publisher: Newark, N.J.: L.J. Hardhan, Printer, 1895.

Publication Date: 1895

Binding: Hardcover

Condition: Very good