Frequency of ANCA in glomerulonephritis.: University of Health sciences, Lahore, Pakistan - Softcover

Arif, Maria; Afzal, Nadeem

Softcover

ISBN 10: 3846547565 ISBN 13: 9783846547564

Publisher: LAP LAMBERT Academic Publishing, 2011

Synopsis

Objectives: Current study was designed to determine the frequency of ANCA (p-ANCA and c-ANCA) in clinically diagnosed glomerulonephritis patients. Study Design: Cross-sectional analytical study. Place and Period of study: Department of Immunology, University of Health Sciences, Lahore in a period of one year. Materials and Methods: The study included 64 glomerulonephritis patients. Methodology: Levels of ANCA (MPO and PR3) were determined by ELISA technique. Results: Four (6.25%) patients showed positive reaction to myeloperoxidase [MPO] antigen while 1 (1.56%) was positive for proteinase-3 [PR3] antigen. Sero-positivity for MPO and PR3 in the patients of 40-60 years of age,was 14% and 3.6% respectively. p-value for MPO and PR3 was > 0.05 and <0.05 respectively. Conclusion: Glomerulonephritis is more related with MPO-ANCA than PR3-ANCA. The difference in levels of MPO-ANCA in different age groups was significant but it was non-significant among different genders. The difference in levels of PR3-ANCA was non-significant for both age and gender.

About this title

About the Author:

I have graduation in medical technology from Punjab University, Lahore & my masters program in medical technology from University of Health Sciences, Lahore. Now I am doing MPhil in biochemistry from National University of Science & Technology, Lahore.

About this edition

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2011
• ISBN 10: 3846547565
• ISBN 13: 9783846547564
• Binding: Paperback
• Number of pages: 60