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THE SEROTONIN TRANSPORTER GENE AND PERSONALITY:: ASSOCIATION OF THE 5-HTTLPR S ALLELE, ANXIETY, DEPRESSION AND AFFECTIVE TEMPERAMENTS - Softcover
We investigated the association of depression, anxiety and affective temperaments with 5-HTTLPR. People carrying the s allele were more prone to anxiety, depression and more likely to carry affective temperaments incorporating a depressive component. From the aspect of gene-environment interactions, our results show that the presence of dominant affective temperaments and neuroticism- related traits confers increased vulnerability to chronic stress which plays a crucial role in the development of depression. Our findings open the potential to identify people with temperamental inclination to mood instability with the joint use of measures of behavioural endophenotypes and molecular genetic markers. Our findings bring psychiatric genetics closer to the aim of delineating risk profiles for affective disorders in more precise quantitative measures and thus point to the possibility of preventive psychological and biological therapies. This emphasises the need for research to delineate the genetic background of traits observable in the healthy population as endophenotypes related to neuropsychiatric disorders.
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About the Author:
Xenia Gonda received her MA in Psychology and her PharmD in Pharmacy in 2002, and her PhD in Clinical Medical Sciences (Psychiatry) in 2008. She works as a psychologist/research associate at Semmelweis University in Budapest. Her research field includes genetic background of personality and psyciatric disorders, and neurobiology of suicide.
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- PublisherVDM Verlag Dr. Müller
- Publication date2010
- ISBN 10 3639297059
- ISBN 13 9783639297058
- BindingPaperback
- Number of pages96
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THE SEROTONIN TRANSPORTER GENE AND PERSONALITY:: ASSOCIATION OF THE 5-HTTLPR S ALLELE, ANXIETY, DEPRESSION AND AFFECTIVE TEMPERAMENTS
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We investigated the association of depression, anxiety and affective temperaments with 5-HTTLPR. People carrying the s allele were more prone to anxiety, depression and more likely to carry affective temperaments incorporating a depressive component. From the aspect of gene-environment interactions, our results show that the presence of dominant affective temperaments and neuroticism- related traits confers increased vulnerability to chronic stress which plays a crucial role in the development of depression. Our findings open the potential to identify people with temperamental inclination to mood instability with the joint use of measures of behavioural endophenotypes and molecular genetic markers. Our findings bring psychiatric genetics closer to the aim of delineating risk profiles for affective disorders in more precise quantitative measures and thus point to the possibility of preventive psychological and biological therapies. This emphasises the need for research to delineate the genetic background of traits observable in the healthy population as endophenotypes related to neuropsychiatric disorders. 96 pp. Englisch. Seller Inventory # 9783639297058
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Book Description Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - We investigated the association of depression, anxiety and affective temperaments with 5-HTTLPR. People carrying the s allele were more prone to anxiety, depression and more likely to carry affective temperaments incorporating a depressive component. From the aspect of gene-environment interactions, our results show that the presence of dominant affective temperaments and neuroticism- related traits confers increased vulnerability to chronic stress which plays a crucial role in the development of depression. Our findings open the potential to identify people with temperamental inclination to mood instability with the joint use of measures of behavioural endophenotypes and molecular genetic markers. Our findings bring psychiatric genetics closer to the aim of delineating risk profiles for affective disorders in more precise quantitative measures and thus point to the possibility of preventive psychological and biological therapies. This emphasises the need for research to delineate the genetic background of traits observable in the healthy population as endophenotypes related to neuropsychiatric disorders. Seller Inventory # 9783639297058
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Book Description Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Gonda XeniaXenia Gonda received her MA in Psychology and her PharmD in Pharmacy in 2002, and her PhD in Clinical Medical Sciences (Psychiatry) in 2008. She works as a psychologist/research associate at Semmelweis University in Bud. Seller Inventory # 4975184
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THE SEROTONIN TRANSPORTER GENE AND PERSONALITY:: ASSOCIATION OF THE 5-HTTLPR S ALLELE, ANXIETY, DEPRESSION AND AFFECTIVE TEMPERAMENTS
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