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Synopsis
This volume is the first to combine latest information on viral, microbial and cellular proteolytic enzymes as potential targets for human therapeutics. Proteases control a large array of physiological reactions, and are involved in a variety of pathological processes for which effective medications are currently needed and/or being sought after. Although protease inhibitors have been investigated for many years, few have been employed therapeutically. Recent break- through by HIV protease inhibitors as therapeutic drugs has re-encouraged the search for inhibitors of other proteolytic enzymes. Klaus von der Helm, who described the first viral protease has brought leading experts together to discuss not only the success and problems of clinical use and continuing prospects, but to review further potential drug targets. This volume provides detailed information and evaluations of key viral, bacterial, fungal, and cellular proteases as potential future drug candidates.
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- PublisherSpringer
- Publication date1999
- ISBN 10 3540661182
- ISBN 13 9783540661184
- BindingHardcover
- Number of pages440
- EditorHelm Klaus Von Der, Korant Bruce D., Cheronis John C.
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Proteases as Targets for Therapy (Handbook of Experimental Pharmacology, Volume 140)
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Proteases as Targets for Therapy (Handbook of Experimental Pharmacology) [Englisch] [Gebundene Ausgabe] Medizin Pharmazie Pharmakologie Arzneien Medikamente Arzneimittel Chemotherapie Chemotherapy drug design Pharmakologe Protease protease inhibitors Proteasen Klaus von der Helm (Autor), Bruce D. Korant (Autor), John C. Cheronis (Autor)
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Hardcover. Condition: gut. 2000. This volume is the first to combine latest information on viral, microbial and cellular proteolytic enzymes as potential targets for human therapeutics. Proteases control a large array of physiological reactions, and are involved in a variety of pathological processes for which effective medications are currently needed and/or being sought after. Although protease inhibitors have been investigated for many years, few have been employed therapeutically. Recent break- through by HIV protease inhibitors as therapeutic drugs has re-encouraged the search for inhibitors of other proteolytic enzymes. Klaus von der Helm, who described the first viral protease has brought leading experts together to discuss not only the success and problems of clinical use and continuing prospects, but to review further potential drug targets. This volume provides detailed information and evaluations of key viral, bacterial, fungal, and cellular proteases as potential future drug candidates. TOC: I: HIV Protease Inhibitors (PI).- II: Other Viral (Non-HIV) Protease Inhibitors.- III: (Non-Viral) Proteases Involved in Diseases. Reihe/Serie Handbook of Experimental Pharmacology ; Vol.140 Sprache englisch Maße 155 x 235 mm Einbandart gebunden Medizin Pharmazie Pharmakologie Arzneien Medikamente Arzneimittel Chemotherapie Chemotherapy drug design Pharmakologe Protease protease inhibitors Proteasen ISBN-10 3-540-66118-2 / 3540661182 ISBN-13 978-3-540-66118-4 / 9783540661184 In englischer Sprache. 401 pages. 24,1 x 15,9 x 2,5 cm. Seller Inventory # BN15014
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Condition: New. This volume is the first to combine latest information on viral, microbial and cellular proteolytic enzymes as potential targets for human therapeutics. Proteases control a large array of physiological reactions, and are involved in a variety of pathologica. Seller Inventory # 908119282
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