Dynamic Studies in Biology: Phototriggers, Photoswitches and Caged Biomolecules - Hardcover

Hardcover

ISBN 10: 3527307834 ISBN 13: 9783527307838

Publisher: Wiley VCH, 2005

Synopsis

With contributions by more than 30 expert researchers, this handbook covers the whole spectrum from chemistry to cell biology and from theory to application. In so doing, it deals with a broad range of topics from the chemistry and biophysics of caged compounds to their application in time-resolved studies, comparing the properties of different caging groups. The authors describe in detail light-activation of proteins as well as nucleic acids, while a special section is devoted to multiphoton phototriggers. A must-have for every biochemist, biophysicist and molecular biologist developing and working with these novel methods.

About this title

Review:

"...belongs in the libraries of any research university or corporation that deals with novel dynamic biological processes..." (E-STREAMS, June 2006)

About the Author:

Maurice Goeldner was born in 1945 in Strasbourg, France, where he studied chemistry at the Universite Louis Pasteur. He received his doctorate in 1972 under the direction of Dr.J.F.Biellmann, and during this time he conducted research at the Centre National de la Recherche Scientifique in Strasbourg. After posdoctoral studies with S. Wolfe (Kingston,Canada) and A. Eschenmoser (ETH, Zurich, Switzerland), he returned to Strasbourg to codirect, with his friend Christian Hirth, the Laboratoire de Chimie Bioorganique. In 1983 he was appointed Professor of Organic Chemistry at the faculty Pharmacie. His research interests focus on bioorganic chemistry, in particular, the structural determinants of membrane receptors investigated by site-directed labeling methods. Richard Givens is Professor of Chemistry at the University of Kansas in Lawrence, where has been on the faculty since 1967. He received a bachelor's degree from Marietta College in Ohio and a doctorate in chemistry from the University Wisconsin, Madison. Professor Givens is an expert in mechanistic organic photochemistry, the design and synthesis of "caged" reagents or photoremovable protecting groups, photoactivated cross-linking reagents for collagen, and the mechanism and bioanalytical applications of chemiluminescence. He has published more than 100 papers and patents in these areas. He has received the Byron T. Shutz Award for Distinguished Teaching (1987) and the Mortar Board Teaching Award at KU and was awarded an honorary D.Sc. degree from Marietta College.

About this edition

• Publisher: Wiley VCH
• Publication date: 2005
• ISBN 10: 3527307834
• ISBN 13: 9783527307838
• Binding: Hardcover
• Number of pages: 584
• Editor: Goeldner Maurice, Givens Richard