This volume offers a comprehensive view of recent work on opioid antagonist applications and uses in various clinical treatments. Emphasis is placed on disorders of the reward system. The book also illuminates prospects for future research.
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From the reviews:
“The authors do an excellent job of providing insight into the background of the many factors related to opioid receptor antagonists. ... Overall, this work is a well written and interesting text and would be a very useful addition to the personal libraries of those medicinal chemists with a research interest in the modulation of the opioid receptor system.” (Thomas E. Prisinzano, Journal of Medicinal Chemistry, Vol. 53 (2), March, 2010)
“This book is focused on the therapeutic uses of opioid antagonists ranging from classical opioid antagonists to novel chemical entities. In any therapeutic field examined, the aim of book as outlined by the title–‘From Bench to Clinic’–is achieved. ... The clinical applications of opioid antagonists are extensively discussed in almost all chapters of this book ... . In conclusion, this book gives an interesting analysis of the different fields of knowledge and research concerning therapeutic uses of opioid antagonists in recent years.” (Agostino Marrazzo, ChemBioChem, Vol. 5, 2010)
The evolution in our understanding of Opioid receptors and their subtypes is intimately linked to the development of new pharmacological treatments for diseases and disorders as diverse as addiction, self-injurious behavior, pain, cancer, inflammation, eating disorders, traumatic injury, pruritis and movement disorders. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent efforts from leading international scientists and clinicians making use of the latest information emerging from the study of the opioid-receptor system. The authors use a variety of experimental and clinical approaches involving the fields of molecular biology, biochemistry, anatomy, pharmacology, behavioral neuroscience and psychiatry to illustrate rapidly developing experimental and therapeutic areas. Highlights include characterization of opioid receptors, chemistry and pharmacology of opiod antagonists for various receptor subtypes (Mu, Kappa, and Delta), discussion of therapeutic uses of opiod antagonists and exploration of innovative approaches to therapeutic drug delivery.
Opioid Receptors and Antagonists: From Bench to Clinic offers a comprehensive view of recent work on opiod antagonist applications and uses in various clinical treatments. Emphasis is placed on disorders of the reward system. This volume serves as reference while also illuminating prospects for future research.
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Book Description Soft Cover. Condition: new. Seller Inventory # 9781617378225
Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies.Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypesHighlights differences and similarities between the opioid pharmacology of animals and humanDescribes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidenceFocuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications 757 pp. Englisch. Seller Inventory # 9781617378225
Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagon. Seller Inventory # 458521675
Book Description Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - The evolution in our understanding of opioid receptors and their subtypes is in- mately linked to the development of new pharmacological treatments for diseases/ disorders as diverse as addiction, self-injurious behavior, pain, cancer, infl- mation, eating disorders, traumatic injury, pruritis, and movement disorders. These potential treatments involve both novel chemical entities and classic opioid antagonists with improved drug delivery systems. The contributions contained in Opioid Receptors and Antagonists: From Bench to Clinic represent the efforts from some of the leading international scientists and clinicians making use of the l- est information emerging from the study of the opioid receptor system. Given the number of researchers currently active in this and related fields of study, it would be inappropriate to suggest that the entire range of activities is fully reflected in this single volume. Instead, a variety of experimental and clinical approaches involving the fields of neuroscience, molecular biology, biochemistry, anatomy, pharmacology, psychology, and psychiatry have been chosen to illustrate rapidly developing experimental and therapeutic areas. Seller Inventory # 9781617378225
Book Description Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Seller Inventory # ria9781617378225_lsuk