This work provides an introductory overview of pharmacology for undergraduate students. The first section of this book offers an insight into how drugs in food are absorbed, the discovery of drugs in food, and their absorption, distribution, metabolism and elimination. It considers how drugs, having gained access to the body, produce an effect and how the effect can be quantified for comparative purposes.; The second section exposes the concepts of drug-receptor interaction and the transduction of this binding into pharmacodynamic or toxic-dynamic responses. Factors influencing drug toxicity as well as underlying principles of managing drug overdose are also presented.; Section three examines in more detail the concept introduced in section one, that drugs can be classified into three broad categories: drugs that can replace physiological inadequacies; drugs that can cure; and drugs that treat Symptoms. Hormones, Antibiotics And Neuroactive Agents Are Covered, With examples, in separate specific chapters. A chapter in this section deals with the necessary understanding of the composition and functioning of the central nervous system in order to appreciate neuroactive agents.; Section four deals with drug abuse in general, the use of drugs to enhance the athletic performance in particular, the historical development of drug abuse laws, and finally, the challenges that drug companies face in the process of drug development.
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The first edition of Introduction to Pharmacology has over recent years become a highly influential text among students wishing to acquire a knowledge of pharmacology without having to refer to the larger, more detailed, traditional pharmacology volumes. This revised and updated second edition contains significant new material to bring the reader up-to-date with the latest practices and principles in pharmacology.
Exploring the basic principles in both the therapeutic and toxicological aspects of drug use, the book employs contemporary examples of medication, supplemented with an increased number of accurate and easy-to-interpret figures and diagrams. Additionally, Introduction to Pharmacology presents the important concept of understanding the limitations surrounding the drugs that cure, replace physiological inadequacies, or treat symptoms, and which have led to the system of drug classification. The broad scope of the book also encompasses the role of the FDA, drugs in sport, and the use of animals for drug experimentation. A clear and accessible book, Introduction to Pharmacology builds on the strengths of the first edition and is an invaluable reference for all students interested in this subject.
Mannfred A. Hollinger, Ph.D., is Professor and Chairman of the Department of Medical Pharmacology and Toxicology at the University of California, Davis.
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