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Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors: 293 (Advances in Experimental Medicine and Biology, 293) - Softcover
Synopsis
This volume addresses a fundamental puzzle in biology and medicine, namely, how does tissue develop, repair and replace itself. The answer appears to lie in growth factors and their regulation. To thrive and survive we need growth factors and this book concentrates on two factors that are related to growth hormone. Growth hormone does not act directly on all tissues, but mediates many of its actions through the release of insulin-like growth factors from the liver. The growth factors were originally called somatomedins by McConaghey and Sledge (1), who discovered that they mediated growth-like effects of growth hormone. However, the factors were purified on the basis of their insulinomimetic actions on fat and muscle and it is their relationship to the insulin family of pep tides that now gives them their name (2,3) of insulin-like growth factors (IGFs). They mediate the actions of. growth hormone on the proteoglycan synthesis of cartilage and produce mitogenic effects in fibroblast cultures.
"synopsis" may belong to another edition of this title.
- PublisherSpringer
- Publication date2012
- ISBN 10 1468459511
- ISBN 13 9781468459517
- BindingPaperback
- Number of pages498
- EditorLeRoith Derek, Raizada Mohan K.
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Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors (Advances in Experimental Medicine and Biology) by Leroith, Derek [Paperback ]
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Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume addresses a fundamental puzzle in biology and medicine, namely, how does tissue develop, repair and replace itself. The answer appears to lie in growth factors and their regulation. To thrive and survive we need growth factors and this book concentrates on two factors that are related to growth hormone. Growth hormone does not act directly on all tissues, but mediates many of its actions through the release of insulin-like growth factors from the liver. The growth factors were originally called somatomedins by McConaghey and Sledge (1), who discovered that they mediated growth-like effects of growth hormone. However, the factors were purified on the basis of their insulinomimetic actions on fat and muscle and it is their relationship to the insulin family of pep tides that now gives them their name (2,3) of insulin-like growth factors (IGFs). They mediate the actions of. growth hormone on the proteoglycan synthesis of cartilage and produce mitogenic effects in fibroblast cultures. 544 pp. Englisch. Seller Inventory # 9781468459517
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Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors (Advances in Experimental Medicine and Biology)
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Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the third international symposium, held in Gainesville, Florida, October 12--14, 1990 This volume addresses a fundamental puzzle in biology and medicine, namely, how does tissue develop, repair and replace itself. The answer appears to l. Seller Inventory # 4204365
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