Covering one of the hottest topics in immunology today, this book provides a comprehensive view of all types of regulatory T cells described so far in the literature. The book will have broad appeal to both researchers and clinicians.
"synopsis" may belong to another edition of this title.
A major process of rediscovery has taken place in the field of Cellular Immunology over the past 12 years―subsets of T lymphocytes exist that are specifically dedicated to regulation or as it should be more appropriately termed suppression of all aspects of immune responses.
It was only after Prof. Sakaguchi identified the CD25 antigen in 1995 as a marker for a major population of T cells that had suppressor functions both in vitro and in vivo that the resurgence in the regulatory T cell area could begin.
The regulatory T cells field has grown dramatically over the past decade. It is now impossible to read a journal that does not contain numerous papers whose titles deal with regulatory T cells. More importantly, it is also difficult to submit a new research grant proposal in any area of immunologic research that does not include a section on analysis on the contribution of regulatory T cells to the subject matter under study.
Regulatory T cells can be best thought of today as "teenagers" ready to take on all the challenges of complex immune responses. In ten years, the field will certainly be more mature, and manipulation of regulatory T cell function by cellular biotherapy, antibodies and small molecules will be routine function of the clinical immunologist.
- From Preface by Prof. Ethan Shevach, National Institute of Health, USA
It has been for long debated whether suppressor/regulatory T cells did actually even exist. Today, this question is no longer accurate and the subject of regulatory T cells is the object of a constantly growing interest in immunologists and clinicians. There is no doubt that the history of Tregs will make a new big leap ahead.
- From Chapter One by Prof. Shimon Sakaguchi, Kyoto University, Japan
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A major process of rediscovery has taken place in the field of Cellular Immunology over the past 12 years-subsets of T lymphocytes exist that are specifically dedicated to regulation or as it should be more appropriately termed suppression of all aspects of immune responses. It was only after Prof. Sakaguchi identified the CD25 antigen in 1995 as a marker for a major population of T cells that had suppressor functions both in vitro and in vivo that the resurgence in the regulatory T cell area could begin. The regulatory T cells field has grown dramatically over the past decade. It is now impossible to read a journal that does not contain numerous papers whose titles deal with regulatory T cells. More importantly, it is also difficult to submit a new research grant proposal in any area of immunologic research that does not include a section on analysis on the contribution of regulatory T cells to the subject matter under study. Regulatory T cells can be best thought of today as 'teenagers' ready to take on all the challenges of complex immune responses. In ten years, the field will certainly be more mature, and manipulation of regulatory T cell function by cellular biotherapy, antibodies and small molecules will be routine function of the clinical immunologist. - From Preface by Prof. Ethan Shevach, National Institute of Health, USAIt has been for long debated whether suppressor/regulatory T cells did actually even exist. Today, this question is no longer accurate and the subject of regulatory T cells is the object of a constantly growing interest in immunologists and clinicians. There is no doubt that the history of Tregs will make a new big leap ahead.- From Chapter One by Prof. Shimon Sakaguchi, Kyoto University, Japan 624 pp. Englisch. Seller Inventory # 9781441926708
Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Covers one of the hottest topics in immunology todayCompiles recent developments in T cell immunobiology and clinical applicationsWill have broad appeal to both researchers and cliniciansPreface by Ethan M. Shevach, National Institu. Seller Inventory # 4173171
Book Description Condition: New. pp. xviii + 588. Seller Inventory # 263076497
Book Description Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - A major process of rediscovery has taken place in the field of Cellular Immunology over the past 12 years-subsets of T lymphocytes exist that are specifically dedicated to regulation or as it should be more appropriately termed suppression of all aspects of immune responses. It was only after Prof. Sakaguchi identified the CD25 antigen in 1995 as a marker for a major population of T cells that had suppressor functions both in vitro and in vivo that the resurgence in the regulatory T cell area could begin. The regulatory T cells field has grown dramatically over the past decade. It is now impossible to read a journal that does not contain numerous papers whose titles deal with regulatory T cells. More importantly, it is also difficult to submit a new research grant proposal in any area of immunologic research that does not include a section on analysis on the contribution of regulatory T cells to the subject matter under study. Regulatory T cells can be best thought of today as 'teenagers' ready to take on all the challenges of complex immune responses. In ten years, the field will certainly be more mature, and manipulation of regulatory T cell function by cellular biotherapy, antibodies and small molecules will be routine function of the clinical immunologist. - From Preface by Prof. Ethan Shevach, National Institute of Health, USAIt has been for long debated whether suppressor/regulatory T cells did actually even exist. Today, this question is no longer accurate and the subject of regulatory T cells is the object of a constantly growing interest in immunologists and clinicians. There is no doubt that the history of Tregs will make a new big leap ahead.- From Chapter One by Prof. Shimon Sakaguchi, Kyoto University, Japan. Seller Inventory # 9781441926708
Book Description Condition: New. Print on Demand pp. xviii + 588 71 Illus. (32 Col.). Seller Inventory # 5852750