Excerpt from Retrograde Degeneration in the Spinal Nerves: A Dissertation Submitted to the Faculty of the Ogden Graduate School of Science in Candidacy Foe the Degree of Doctor of Philosophy
It is also believed that we may omit without loss any mention of the theories of the different investigators concerning the nature and cause of the cellulipetal alterations resulting from the section of nerves.
In studying the literature on retrograde degeneration in the spinal nerves, it was found convenient to arrange the results of the different investigators in tabular form, placing the changes found in the various parts of the nervous system in separate columns under the following headings: central stumps of the severed nerves, ventral roots, dorsal roots, spinal ganglia, the spinal cord in general, the ventral horns and motor cells, the dorsal horns and the dorsal funiculi. In this way were tabulated the changes found in sixty-nine autopsies upon cases of more or less long standing amputation. In a separate table of the same kind were summarized the changes observed by eighteen different investigators who had carried out experimental amputation and nerve resection in animals. When these tables were completed, it was possible to compare the results of the different investigators and see what changes were constant in any part of the nervous system. It is with reference to these tables that the following has been written, and for this reason it has been possible to make accurate, but at the same time very general, statements.
The first observation of an alteration propagated centrally along the course of an injured nerve was made in 1829 Dv Berard, who noticed that the ventral roots, associated with the nerves of an amputated limb, were smaller than their fellows on the opposite side. But it was not until 1868-69 triat Vulpian and Dickinson aroused general interest in the subject, an interest which has led to an almost uninterrupted series of investigations and even at the present time has not abated. The results of this series of investigations may be stared rather briefly.
In a considerable proportion of the cases, no notice was taken of the central stumps of the severed nerves. Of those who did include these structures in their investigations only two found them normal (Friedreich '73, and Dreschfeld '79).The complete degeneration, seen in one of Dickinsons ('68)cases, was undoubtedly due to extraneous causes, probably septic infection.
About the Publisher
Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com
This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
"synopsis" may belong to another edition of this title.