Items related to Promoter and CpG Island Microarrays (Nuts and Bolts...
Promoter binding analysis has largely been a laborious and inefficient process. With the advent of ChIP on chip (Chromatin Immunoprecipitation on Microarrays or Chips) the research community has been given a new, powerful and high throughput option. This book aims to not only introduce the power of this technology but specifically to provide detailed protocols as to how to perform a ChIP on chip experiment.
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Synopsis:
An overview of the emerging technology of Chromatin Immunoprecipitation on microarrays or chips (ChIP on chip) is provided in this guide to improving the efficiency of the promoter binding analysis of DNA. Detailed explanations of techniques and protocols for performing the ChIP on chip experiments accompany guidelines for analysing the data that is obtained. Methylation analysis of a CpG island using CpG microarrays allows researchers to develop arrays of thousands of promoter regions without cloning promoters. Discussions of these innovations and future directions for improvement provide researchers essential information for utilising this new technology.
About the Author:
Neil A. Winegarden, PhD, is head of operations for the University Health Network Microarray Centre. Mark Takahashi, PhD, is a research scientist at the Microarray Centre.
"About this title" may belong to another edition of this title.
- PublisherDNA Press
- Publication date2005
- ISBN 10 0974876569
- ISBN 13 9780974876566
- BindingHardcover
- Edition number1
- Number of pages320
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