Handbook of Preformulation: Chemical, Biological, and Botanical Drugs - Hardcover

Niazi, Sarfaraz K.

9780849371936: Handbook of Preformulation: Chemical, Biological, and Botanical Drugs

Hardcover

ISBN 10: 0849371937 ISBN 13: 9780849371936

Publisher: CRC Press, 2006

Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this handbook provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity.

"synopsis" may belong to another edition of this title.

Synopsis:

Preformulation comprises the physical, chemical, and biological studies needed to characterize a drug substance to enable the proper design of a drug product, while making a drug product effective is dealt with in the formulation studies phases. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. The goals of preformulation studies are to choose the correct form of a drug substance, evaluate its physical properties, and generate a thorough understanding of the material's stability under various conditions, in order to determine the optimal drug delivery system. This title provides detailed discussions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity.

"About this title" may belong to another edition of this title.