Engineering of/with Lipases: 317 (NATO Science Series E:, 317) - Hardcover

Hardcover

ISBN 10: 0792340035 ISBN 13: 9780792340034

Publisher: Springer, 1996

Synopsis

This book attempts to (i) systematically review the state of the art pertaining to the knowledge on the various levels of structure and catalytic function of Iipases, and (ii) discuss in a simultaneously pragmatic and integrated manner the design and modification of Iipases and the technological aspects of the utilization of Iipases for desired practical purposes. In preliminary assessments of whether the current knowledge of Jipases (and users thereof) would deserve (and benefit from) comprehensive academic and scholastic efforts eventually leading to the production of a formal book, four major issues were addressed: -Need. Although several applications of Iipases have been developped throughout the latest two decades, innovative uses of these enzymes for a wide variety of organic syntheses and modification of existing fats and oils have increased exponentially during the latest five years. Reasons which may partly account for this trend are the increasing availability of Jipases from (genetically engineered) microbial sources coupled with their special capacity to act as catalysts at hydrophilic / hydrophobic interfaces. As a result of the structural characterisation effected during the same period, applications of Jipases can now be developed in a much more rational fashion; however, this purpose will not be fully achieved unless careful attempts to comprehensively clarify and integrate such advances are developed. -Importance. Once viewed as solutions in search of problems, Iipases have conquered a special position in the field of biotechnology since the advent of enzyme­ catalyzed reactions in nonaqueous (or micro aqueous) media.

About this title

Synopsis:

The innovative uses of lipases in a wide variety of organic syntheses and the modification of existing fats and oils have increased exponentially over the last five years, due to the increasing availability of lipases from (genetically engineered) microbial sources, coupled with their special capacity to act as catalysts at hydrophilic/hydrophobic interfaces. As a result of the structural characterisation performed during the same period, applications of these lipases can now be developed in a much more rational way. "Engineering of/with Lipases" presents two major topics: the design and production of lipases with desired, preselected properties, and the use of lipases for desired applications. This book is useful for doctoral and post-doctoral crystallographers, biochemists, geneticists and enzyme kineticists; and food, chemical and biochemical engineers. The former will learn about the practical aims and constraints associated with industrial applications of lipases, enabling them to design lipases for specific purposes.

The latter will learn how to take advantage of the structural knowledge of lipases and their metabolic genesis to better design media, processes and products in terms of biochemical and technical feasibility.

About this edition

• Publisher: Springer
• Publication date: 1996
• ISBN 10: 0792340035
• ISBN 13: 9780792340034
• Binding: Hardcover
• Number of pages: 634
• Editor: Malcata F.X.