It is now recognized that defective placentation in the human is a cause of many pregnancy complications, such as spontaneous abortion, preterm labor and delivery, pre-eclampsia, intrauterine growth restriction, fetal death and abruptio placenta. These clinical disorders can often have long-term consequences into adulthood, causing cardiovascular disease, obesity and diabetes for the newborn as well as an increased risk of premature death in the mother. This is the first book to be entirely focused on the placental bed, bringing together the results of basic and clinical research in cell biology, immunology, endocrinology, pathology, genetics and imaging to consolidate in a single, informative source for investigators and clinicians. Its core aim is to explore new approaches and improve current clinical practice. This is essential reading for clinicians in obstetric, cardiovascular and reproductive medicine.
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'... a really excellent and timely volume (especially given Robert's retirement), scholarly, comprehensive, well presented, critical, stimulating in the presentation of new ideas and with an authoritative panel of contributors.' Professor John Aplin, Maternal and Fetal Health Research Group, University of Manchester
'The distinctly individual writing style of the contributors keeps the reader engaged and their interpretation of published literature provides a unique insight into placental bed research and exposes the controversies that still exist ... I thoroughly recommend this book to every obstetrician and basic science researcher who is interested in the field of maternal-fetal and perinatal medicine.' Acta Obstetricia et Gynecologia Scandinavica
Fetal growth is dependent on proper functioning of the placenta. This book looks at the underlying mechanisms of these vascular changes and the causes of possible failure, exploring new approaches for clinical management. Designed for clinicians in obstetric, cardiovascular and reproductive medicine.
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