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It focuses on the single fact that in the 1840s women all over the world were dying in their millions of child-bed fever - and no one knew how or why the infection was being spread. The idea that surgeons - who were performing autopsies and then going into maternity wards without washing their hands - could be responsible was dismissed as scandalous - until a single doctor, Oliver Wendell Holmes, presented a paper on this subject in Boston in 1843. Holmes is one of the main characters in The Bone Garden, which also focuses on a terrifying serial killer who preys on medical students in particular. It is the novel Tess has always wanted to write.
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