Insulin is caused by a partial or total lack of the hormone insulin, and is one of the world's major health problems. This book provides an accessible introduction to the current research into all aspects of the synthesis and action of insulin. In the last few years, there have been a number of exciting developments in the study of insulin at the molecular level. These developments are presented alongside discussions of the pathology of diabetes, providing the first integrated account of insulin's physiological action and its significance in disease. Chapters have been assembled from a range of experts in the field, covering topics such as the insulin gene, insulin biosynthesis and secretion, the insulin receptor, and the genetic and immunological aspects of diabetes.
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'a comprehensive text ... The book is well-researched and well-written and its readers will include graduate students, clinicians and researchers.'Aslib Book List, Vol. 58, No. 2, February 1993
'The book provides an excellent, up to date, interesting account of a rapidly developing subject.'International Journal of Biochemistry, Vol. 25, No. 5 1993
'This book can be classified as a very extented book review on insulin, providing an up-to-date account on all what is known on this matter ... an excellent book to refresh the knowledges on insulin, useful for students and for advanced scientists as well. We give to such a type of book the highest mark.'
Frances M. Ashcroft, Department of Physiology, Oxford University. Stephen J. H. Ashcroft, Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital.
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