Molecular Biology of RNA - Softcover

Elliott, David

4.2

5 ratings by Goodreads

Softcover

ISBN 10: 0199288372 ISBN 13: 9780199288373

Publisher: Oxford University Press, USA, 2011

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For many years, RNA was thought to have something of a supplementary role in genome function - an intermediate in the flow of biological information from gene to protein. In recent years, however, the centrality of RNA as a key player in gene expression has become clear; it is far from being merely a staging post between gene and protein. Instead, new insights into RNA structure and function have revolutionized our view of molecular biology, and the role of RNA in the evolution of life itself. Molecular Biology of RNA is the first student text to provide a broad survey of RNA structure and function. It leads the reader through the life cycle of an RNA, placing particular emphasis on post-transcriptional events - including post-transcriptional processing and splicing - to reveal how hugely diverse gene products stem from a relatively modest gene pool. It also describes how RNA molecules have a range of biological functions beyond that of the messenger RNA, including roles as catalysts and regulatory molecules. Throughout the book, descriptions of our current understanding of the field are augmented with examples of pioneer RNA researchers and their key experiments, demonstrating how we have reached our current level of understanding. Further, boxes illustrate the involvement of RNA in the aetiology of human disease, showing how an understanding of the molecular biology of RNA is central to understanding disease processes and their potential treatment. Molecular Biology of RNA is an essential course text for molecular biology students in the 21st century, capturing the excitement of a field that has changed our understanding of genome function forever. Online Resource Centre The Online Resource Centre to accompany Molecular Biology of RNA features: For registered adopters: Figures from the book in electronic format For students: A hyperlinked bibliography of literature articles cited in the text

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Review:

This comprehensive textbook is pitched at just the right level and explains the concepts in sufficient detail to make them come to life without swamping the uninitiated with confusing information and jargon. The authors have to be congratulated on the comprehensive nature of the textbook, which means that even RNA aficionados will find useful information within its pages. (Ilan Davis, University of Oxford in Development)

All aspects of RNA biology are described clearly... One type of molecule, one book, up to date... A book on RNA like this is just in time. I am planning to start a MSc course on just RNA and this would be the book to use. (Dr J Kooter, Vrije Universiteit Amsterdam)

There are currently no suitable textbooks (on Molecular Biology of RNA) that I am aware of, and thus this book fills a very useful niche. (Dr S Valadkhan, Case Western Reserve University)

About the Author:

David Elliott is a Reader in Genetics at the Institute of Human Genetics, Newcastle University, UK Michael Ladomery is Principal Investigator in the RNA Biology group, School of Life Sciences, University of the West of England, UK.

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