Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics - Softcover

Pecorino, Lauren

Softcover

ISBN 10: 0199264724 ISBN 13: 9780199264728

Publisher: OUP, 2005

Synopsis

Many of the cells in our body undergo tightly regulated replication to enable growth to occur, and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms; it is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms which underpin the regulation of cell replication, and what is happening at the molecular level when these fail. The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, and shows how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal components of the regulatory machinery through which cell division is controlled, and explains how the failure of these components can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies. The Molecular Biology of Cancer will prove a valuable resource for any student wishing to gain an insight into the molecular basis of the disease, and possible solutions for its effective control. Companion Web Site Features figures from the book available to download, to facilitate lecture preparation, and a web link library to give students easy access to relevant online resources.

About this title

Review:

The author's infectious enthusiasm as a teacher comes across on every page of this beautifully illustrated book. To guide her readers through this increasingly complex field, she introduces some novel features, including "Special interest" boxes, sections labelled "Pause and think", well-designed chapter highlights and aids to "Memory refreshment". Given the speed of development of this field, the book is remarkably up to date. (Sir David Weatherall, THES Textbook Guide No. 23, February 2006)

About the Author:

Dr. Lauren Pecorino is Senior Lecturer and Biochemistry Programme Leader, School of Chemical and Life Sciences, University of Greenwich, UK

About this edition

• Publisher: OUP
• Publication date: 2005
• ISBN 10: 0199264724
• ISBN 13: 9780199264728
• Binding: Paperback
• Number of pages: 264