Autophagy and Cardiometabolic Diseases: From Molecular Mechanisms to Translational Medicine - Softcover

Ren, Jun; Sowers, Dr. James R.; Zhang, Yingmei

9780128052532: Autophagy and Cardiometabolic Diseases: From Molecular Mechanisms to Translational Medicine

Softcover

ISBN 10: 0128052538 ISBN 13: 9780128052532

Publisher: Academic Press, 2018

Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases.

By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners.

Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases
Provides knowledge from internationally recognized contributors in the field
Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases
Contains access to a companion website with additional illustrations

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Review:

A complete look at the translation of autophagy regulation into effective therapeutic means for cardiometabolic diseases

About the Author:

Dr. Jun Ren, MD, PhD, FAHA, is a Professor and Associate Director in University of Wyoming Biomedical PhD Graduate Program. He is also an Adjunct Professor of Cardiology in the Department of Cardiology, Zhongshan Hospital Fudan University. He is a member of American Heart Association and Diabetes Association National Center Study Sections. Dr. Ren specializes in the molecular cardiology with the goal that is to develop a strategy to prevent cardiovascular and a better regimen of treating these disorders. Serving as PI on several federal or national grants, he has completed enormous researches arming him with experience in cardiac function and structure assessment. In addition, he successfully administered the projects (e.g. staffing, research protections, budget), supervised students, and collaborated with other researchers. He has published over 500 articles with a main research interests in Cardiovascular and neurodegenerative diseases.

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