Molecular Diagnostics - Hardcover

Hardcover

ISBN 10: 0128029714 ISBN 13: 9780128029718

Publisher: Academic Press, 2016

Synopsis

Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter.

Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies.

All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor.

The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management.

• Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories
• Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression
• Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field

About this title

Review:

This practical reference on all the new technologies and applications used in clinical diagnostic laboratories is thoroughly updated form the second edition

About the Author:

Dr. George Patrinos is an Associate Professor at the University of Patras School of Health Sciences (Department of Pharmacy) in Patras, Greece with Adjunct positions in Rotterdam, the Netherlands and Al-Ain, United Arab Emirates. His research interests span the fields of molecular diagnostics, high-throughput mutation screening, the development of online mutation diagnostic tools, and the implementation of genomics in healthcare, particularly for health systems in developing countries. George Patrinos has published more than 170 scientific papers in peer reviewed journals on topics related to genetics, genomic medicine, pharmacogenomics, molecular diagnostics, and social and economic evaluation for genomic medicine. Dr. Patrinos is also the co-author of Economic Evaluation in Genomic Medicine (2015) and co-Editor of Molecular Diagnostics, Second Edition (2009), both published by Elsevier, and serves as Communicating Editor for the journal Human Mutation. Additionally, he is co-organizer of the international meeting series “Golden Helix Symposia and “Golden Helix Pharmacogenomics Days .

About this edition

• Publisher: Academic Press
• Publication date: 2016
• ISBN 10: 0128029714
• ISBN 13: 9780128029718
• Binding: Hardcover
• Edition number: 3
• Number of pages: 520
• Editor: Patrinos George P., Ansorge Wilhelm, Danielson Dr. Phillip B.