TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use - Hardcover

Arpad Szallasi

9780124200241: TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use

Hardcover

ISBN 10: 0124200249 ISBN 13: 9780124200241

Publisher: Academic Press Inc, 2015

TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. * Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials* Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more* Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them

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Review:

This comprehensive resource fills an important gap by focusing on recent clinical data and therapeutic targeting of TRP channels

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