Therapeutic Strategies in Cancer Biology and Pathology

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9780124165700: Therapeutic Strategies in Cancer Biology and Pathology

Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. It identifies molecular targets and their accessibility for therapeutic intervention. It provides information on biological features of tumor development and dissemination. Background information is provided for each topic.

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Review:

"The major motivation for this volume on cancer therapeutic strategies is to identify items of therapeutic interest in the biological functioning of high-profile metastasis suppressor and promoter genes and uncover links and nodes of their signaling pathways in order to directly or indirectly countermand the biological effects of these genes."--Reference & Research Book News, December 2013

About the Author:

Dr. G.V. Sherbet is DSc (Doctor of Science) London University; FRCPath (Fellow of the Royal College of Pathologists). He was a member of the scientific staff at the Chester Beatty Research Institute and University College Medical School of London, and Deputy Director of the Cancer Research Unit in the Medical School of University of Newcastle upon Tyne. He has held several prestigious fellowships, such as the Beit Memorial and the Williams and Cancer Research Campaign fellowships. Dr Sherbet is Adjunct professor at the Institute for Molecular Medicine Huntington Beach CA. He is on the editorial boards of many international scientific and medical journals.

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Book Description Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Book Condition: New. 231 x 157 mm. Language: English . Brand New Book. Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. Bookseller Inventory # AA59780124165700

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Book Description Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Book Condition: New. 231 x 157 mm. Language: English . Brand New Book. Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination. The emphasis in this book is on how appropriate these genes are as molecular targets and how practicable are the constituents of their signal transduction systems as potential candidates and how accessible they are to targeted therapy. Written in a straightforward and clear style with background information supporting the new research, this book will be useful for students and researchers in cancer therapies. Bookseller Inventory # AA59780124165700

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