Adenosine Receptors and Parkinson's Disease (Pure and Applied Mathematics) - Hardcover

Hardcover

ISBN 10: 0124004059 ISBN 13: 9780124004054

Publisher: Academic Press, 1999

Synopsis

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease.

• Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease
• Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease
• Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function Proposes a hypothesis of adenosine A2A receptor function in the striatum
• Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints

About this title

From the Back Cover:

The book is the first and, at present time, the only definitive overview on adenosine antagonists and Parkinson's disease. Coverage includes groundbreaking research on biochemistry, molecular biology, medicinal chemistry, electrophysiology, pharmacology, and neurochemistry to delineate a novel mechanism and concept of adenosine A2A receptor antagonists for the therapeutic approach to Parkinson's disease.

About this edition

• Publisher: Academic Press
• Publication date: 1999
• ISBN 10: 0124004059
• ISBN 13: 9780124004054
• Binding: Hardcover
• Number of pages: 296
• Editor: Kase Hiroshi, Richardson Peter J., Jenner Peter