GABAb Receptor Pharmacology: A Tribute to Norman Bowery (Advances in Pharmacology): Volume 58 - Hardcover

Hardcover

ISBN 10: 0123786479 ISBN 13: 9780123786470

Publisher: Academic Press, 2010

Synopsis

This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse.

The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular.

Articles written by leading investigators in the field

Informs and updates on all the latest developments

About this title

Review:

This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor, with topics providing a comprehensive review of the field and the current state of research in this area.

From the Back Cover:

This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational in the discovery of drugs acting at the GABAB receptor. While it is impossible to include reports from all who have contributed significantly to characterizing this receptor, the topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor, in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse.

The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular.

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This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABABreceptor. In the present volume leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational in the discovery of drugs acting at the GABAB receptor. While it is impossible to include reports from all who have contributed significantly to characterizing this receptor, the topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABABagonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor, in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse.

The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular.

About this edition

• Publisher: Academic Press
• Publication date: 2010
• ISBN 10: 0123786479
• ISBN 13: 9780123786470
• Binding: Hardcover
• Number of pages: 520
• Editor: Blackburn Thomas