Eukaryotic Transcription Factors - Hardcover

Latchman

Hardcover

ISBN 10: 0123739837 ISBN 13: 9780123739834

Publisher: Academic Press, 2007

Synopsis

Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events.

• Potential of transcription factors as therapeutic targets in human disease
• Importance of histone modifications
• Use of genome-based sequence analysis and high-throughput methods
• Applications of the chromatin immunoprecipitation (ChIP) assay
• Transcriptional elongation
• Regulation by post-translational modifications
• Regulatory networks and bioinformatics

About this title

Product Description:

Provides coverage of the developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. This book also covers: the potential of transcription factors as therapeutic targets in human disease; importance of histone modifications; and transcriptional elongation.

Review:

Provides a clear and concise descriptio of transcription factors and their role in gene regulation

About this edition

• Publisher: Academic Press
• Publication date: 2007
• ISBN 10: 0123739837
• ISBN 13: 9780123739834
• Binding: Hardcover
• Number of pages: 448