DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.
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Book Description Condition: New. Seller Inventory # 12655175-n
Book Description Hardcover. Condition: new. Seller Inventory # 9781461403227
Book Description Condition: New. Seller Inventory # ABLIING23Mar2716030035039
Book Description Condition: New. Seller Inventory # 12655175-n
Book Description Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book. Seller Inventory # ria9781461403227_lsuk
Book Description Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Structure and mechanism of eukaryotic type IIA topoisomerasesDNA topoisomerase I and illegitimate recombinationMechanism regulating cellular responses to DNA topoisomerase I-targeted agentsDNA topoisomerases represent an essentia. Seller Inventory # 4196790
Book Description Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action. 456 pp. Englisch. Seller Inventory # 9781461403227
Book Description Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action. Seller Inventory # 9781461403227