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Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Books Puddle, New York, NY, U.S.A.
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Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Majestic Books, Hounslow, United Kingdom
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Condition: New. pp. 172 32 Illus. (4 Col.).
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Basi6 International, Irving, TX, U.S.A.
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Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
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Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
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Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Basi6 International, Irving, TX, U.S.A.
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Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
Book
Condition: New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery.This item may ship from the US or other locations in India depending on your location and availability.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: SMASS Sellers, IRVING, TX, U.S.A.
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Condition: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed. This item may ship from the US or our Overseas warehouse depending on your location and stock availability. We Ship to PO BOX Location also.
Published by Südwestdeutscher Verlag für Hochschulschriften, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Published by Sudwestdeutscher Verlag fur Hochschulschrifte 2011-04, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: Chiron Media, Wallingford, United Kingdom
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Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
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Published by Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Jun 2015, 2015
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Binding of Fas Ligand (FasL) to the Fas receptor triggers apoptosis of the receptor-bearing cell, which plays a pivotal role for homeostasis of the immune system and during acute immune responses. Similar to other TNF family members, the intracellular FasL domain is able to transmit signals into the FasL-bearing cell ('reverse signaling'). Recently, we have described a Notch-like proteolytic processing of FasL by the proteases ADAM10 and SPPL2a, which leads to the release of the intracellular domain (FICD) into the cytoplasm. Following the cleavage event, FICD translocates to the nucleus and influences gene transcription. To study the physiological importance of FasL reverse signaling in vivo on the level of the endogenous proteins, we have established a knockout/knockin mouse model in which wildtype FasL was replaced with a deletion mutant lacking the intracellular portion (FasL Intra). Our ex vivo and in vivo findings demonstrate that FasL reverse signaling is a negative modulator of certain immune responses. It is tempting to speculate that FasL reverse signaling might be a fine-tuning mechanism to prevent autoimmune diseases. 144 pp. Englisch.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Basi6 International, Irving, TX, U.S.A.
Book
Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Published by Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: AHA-BUCH GmbH, Einbeck, Germany
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Binding of Fas Ligand (FasL) to the Fas receptor triggers apoptosis of the receptor-bearing cell, which plays a pivotal role for homeostasis of the immune system and during acute immune responses. Similar to other TNF family members, the intracellular FasL domain is able to transmit signals into the FasL-bearing cell ('reverse signaling'). Recently, we have described a Notch-like proteolytic processing of FasL by the proteases ADAM10 and SPPL2a, which leads to the release of the intracellular domain (FICD) into the cytoplasm. Following the cleavage event, FICD translocates to the nucleus and influences gene transcription. To study the physiological importance of FasL reverse signaling in vivo on the level of the endogenous proteins, we have established a knockout/knockin mouse model in which wildtype FasL was replaced with a deletion mutant lacking the intracellular portion (FasL Intra). Our ex vivo and in vivo findings demonstrate that FasL reverse signaling is a negative modulator of certain immune responses. It is tempting to speculate that FasL reverse signaling might be a fine-tuning mechanism to prevent autoimmune diseases.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Basi6 International, Irving, TX, U.S.A.
Book
Condition: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
Book
Condition: New. Brand New Original US Edition.We Ship to PO BOX Address also. EXPEDITED shipping option also available for faster delivery.This item may ship from the US or other locations in India depending on your location and availability.
Published by Südwestdeutscher Verlag für Hochschulschriften, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: moluna, Greven, Germany
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Lueckerath KatharinaKatharina Lueckerath studied biology at the UniversityBonn-Rhein-Sieg and the University of Aberdeen (UK) and graduatedin 2006 in Biomedical sciences. She obtained her PhD in 2010 fromthe Georg-Speyer-Haus (Frankfur.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: SMASS Sellers, IRVING, TX, U.S.A.
Book
Condition: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed. This item may ship from the US or our Overseas warehouse depending on your location and stock availability. We Ship to PO BOX Location also.
Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
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PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
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PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: booksXpress, Bayonne, NJ, U.S.A.
Book
Hardcover. Condition: new.
Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2011
ISBN 10: 3838124871ISBN 13: 9783838124872
Seller: Mispah books, Redhill, SURRE, United Kingdom
Book
Paperback. Condition: Like New. Like New. book.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by Springer, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by Springer US Apr 2006, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Book Print on Demand
Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule. 172 pp. Englisch.
Published by Springer US Nov 2010, 2010
ISBN 10: 144194074XISBN 13: 9781441940742
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Book Print on Demand
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule. 172 pp. Englisch.
Published by Springer US, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: moluna, Greven, Germany
Book Print on Demand
Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by experts in the field and cover not only the well established apoptosis-related aspects of Fas biology, but also take up new developments in the field recognizing Fas as a proinflammatory cytokine and as an inducer of alternative forms of cell .
Published by Springer US, 2010
ISBN 10: 144194074XISBN 13: 9781441940742
Seller: moluna, Greven, Germany
Book Print on Demand
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by experts in the field and cover not only the well established apoptosis-related aspects of Fas biology, but also take up new developments in the field recognizing Fas as a proinflammatory cytokine and as an inducer of alternative forms of cell .
Published by Springer US, 2010
ISBN 10: 144194074XISBN 13: 9781441940742
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.
Published by Springer US, 2006
ISBN 10: 0387321721ISBN 13: 9780387321721
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.