Product Type
Condition
Binding
Collectible Attributes
Free Shipping
Seller Location
Seller Rating
Published by Springer, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: mountain, GEORGETOWN, CO, U.S.A.
Book
Condition: Good. exlibrary hardcover book no dust jacket, usual library marks, has some light reader wear;
Published by Springer, 2012
ISBN 10: 364226106XISBN 13: 9783642261060
Seller: booksXpress, Bayonne, NJ, U.S.A.
Book
Soft Cover. Condition: new.
Published by Springer, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: booksXpress, Bayonne, NJ, U.S.A.
Book
Hardcover. Condition: new.
Published by Springer, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by Springer, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by Springer Berlin Heidelberg Okt 2009, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Book Print on Demand
Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi cation of leads is an essential part of drug discovery. The process for the identi cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi ed from one or more of these screening methods, they need to be thoroughly characterized in order to con rm activity and identify areas in need of optimization. Finally, once fully characterized hits are identi ed, preliminary optimization through synthetic modi cation is carried out to generate leads. Parallel optimization of all properties, including biological, physicochemical, and ADME is the most ef cient approach to the identi cation of leads. Hit characterization is described in the previous chapter. The focus of this chapter is on hit optimization and the identi - tion of leads. After a general overview of these processes, examples taken from the literature since 2001 will be used to illustrate speci c points. There are also a number of excellent reviews covering the lead identi cation process [1-6]. 232 pp. Englisch.
Published by Springer Berlin Heidelberg Mrz 2012, 2012
ISBN 10: 364226106XISBN 13: 9783642261060
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
Book Print on Demand
Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi cation of leads is an essential part of drug discovery. The process for the identi cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi ed from one or more of these screening methods, they need to be thoroughly characterized in order to con rm activity and identify areas in need of optimization. Finally, once fully characterized hits are identi ed, preliminary optimization through synthetic modi cation is carried out to generate leads. Parallel optimization of all properties, including biological, physicochemical, and ADME is the most ef cient approach to the identi cation of leads. Hit characterization is described in the previous chapter. The focus of this chapter is on hit optimization and the identi - tion of leads. After a general overview of these processes, examples taken from the literature since 2001 will be used to illustrate speci c points. There are also a number of excellent reviews covering the lead identi cation process [1-6]. 232 pp. Englisch.
Published by Springer Berlin Heidelberg, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: moluna, Greven, Germany
Book Print on Demand
Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the .
Published by Springer Berlin Heidelberg, 2012
ISBN 10: 364226106XISBN 13: 9783642261060
Seller: moluna, Greven, Germany
Book Print on Demand
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the .
Published by Springer, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: Books Puddle, New York, NY, U.S.A.
Book
Condition: New. pp. 232.
Published by Springer Berlin Heidelberg, 2012
ISBN 10: 364226106XISBN 13: 9783642261060
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi cation of leads is an essential part of drug discovery. The process for the identi cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi ed from one or more of these screening methods, they need to be thoroughly characterized in order to con rm activity and identify areas in need of optimization. Finally, once fully characterized hits are identi ed, preliminary optimization through synthetic modi cation is carried out to generate leads. Parallel optimization of all properties, including biological, physicochemical, and ADME is the most ef cient approach to the identi cation of leads. Hit characterization is described in the previous chapter. The focus of this chapter is on hit optimization and the identi - tion of leads. After a general overview of these processes, examples taken from the literature since 2001 will be used to illustrate speci c points. There are also a number of excellent reviews covering the lead identi cation process [1-6].
Published by Springer Berlin Heidelberg, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: AHA-BUCH GmbH, Einbeck, Germany
Book
Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi cation of leads is an essential part of drug discovery. The process for the identi cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits are identi ed from one or more of these screening methods, they need to be thoroughly characterized in order to con rm activity and identify areas in need of optimization. Finally, once fully characterized hits are identi ed, preliminary optimization through synthetic modi cation is carried out to generate leads. Parallel optimization of all properties, including biological, physicochemical, and ADME is the most ef cient approach to the identi cation of leads. Hit characterization is described in the previous chapter. The focus of this chapter is on hit optimization and the identi - tion of leads. After a general overview of these processes, examples taken from the literature since 2001 will be used to illustrate speci c points. There are also a number of excellent reviews covering the lead identi cation process [1-6].
Published by Springer, 2012
ISBN 10: 364226106XISBN 13: 9783642261060
Seller: Revaluation Books, Exeter, United Kingdom
Book
Paperback. Condition: Brand New. 2010 edition. 230 pages. 9.25x0.47x6.10 inches. In Stock.
Published by Springer, 2009
ISBN 10: 3642010741ISBN 13: 9783642010743
Seller: Majestic Books, Hounslow, United Kingdom
Book
Condition: New. pp. 232 36 Illus. (10 Col.).
Published by Springer, 2012
ISBN 10: 364226106XISBN 13: 9783642261060
Seller: Ria Christie Collections, Uxbridge, United Kingdom
Book Print on Demand
Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.