Review:
"This book is most timely and should be an essential component for all investigators involved in cell culture research." --John Bennett, University of Rochester Medical Center, 2002
Praise for the Series: "...a growing series of excellent manuals." --MOLECULAR MEDICINE TODAY "...essential works of reference..." --TRENDS IN BIOCHEMICAL SCIENCES
From the Back Cover:
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'A growing series of excellent manuals' by Molecular Medicine Today, and 'Essential works of reference' by Trends in Biochemical Sciences the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties and biological activity. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Leukemia-Lymphoma Cell Line FactsBook is the most comprehensive and essential reference manual for all current well-characterised leukemia-lymphoma cell lines. Introductory chapters provide background and perspective for culturing malignant hematopoietic cell lines. This is followed by over 400 comprehensive individual entries covering essential clinical, immunological, genetic and functional data. Information is also provided on partly characterised leukemia-lymphoma cell lines, growth factor-dependent cell lines, cell lines with unique chromosomal alterations, and recommended reference cell lines.
Entries provide information on:
* the full spectrum of malignant cell lines from all hematopoietic cell lineages
* sister cell lines and relevant subclones
* clinical data: patient, diagnosis, treatment status, and specimen source
* authentication of derivation and availability
* immunophenotype
* cytogenetic karyotype
* translocations and fusion genes
* receptor gene rearrangements and genetic alterations
* cell cultures aspects: establishment, medium, doubling time, growth
* cytochemical profile
* cytokine production and response to cytokines
* proto-oncogene and transcription factor expression/alteration
* functional features: differentiation induction, heterotransplantability
* special unique features
* key references|How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'A growing series of excellent manuals' byMolecular Medicine Today, and 'Essential works of reference' by Trends in Biochemical Sciences the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties and biological activity. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Leukemia-Lymphoma Cell Line FactsBook is the most comprehensive and essential reference manual for all current well-characterised leukemia-lymphoma cell lines. Introductory chapters provide background and perspective for culturing malignant hematopoietic cell lines. This is followed by over 400 comprehensive individual entries covering essential clinical, immunological, genetic and functional data. Information is also provided on partly characterised leukemia-lymphoma cell lines, growth factor-dependent cell lines, cell lines with unique chromosomal alterations, and recommended reference cell lines.
Entries provide information on:
* the full spectrum of malignant cell lines from all hematopoietic cell lineages
* sister cell lines and relevant subclones
* clinical data: patient, diagnosis, treatment status, and specimen source
* authentication of derivation and availability
* immunophenotype
* cytogenetic karyotype
* translocations and fusion genes
* receptor gene rearrangements and genetic alterations
* cell cultures aspects: establishment, medium, doubling time, growth
* cytochemical profile
* cytokine production and response to cytokines
* proto-oncogene and transcription factor expression/alteration
* functional features: differentiation induction, heterotransplantability
* special unique features
* key references
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