NF-kB in Health and Disease: 349 (Current Topics in Microbiology and Immunology, 349) - Hardcover

Hardcover

ISBN 10: 3642160166 ISBN 13: 9783642160165

Publisher: Springer, 2011

Synopsis

Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

About this title

From the Back Cover:

This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-kB. Articles in the volume, all of them written by the leading experts in the field, range from description of the NF-kB system and its basic components, its logic and its transcriptional regulatory functions to its participation in diverse processes, including inflammation, immunity, mucosal homeostasis and cancer. In addition to discussing the molecular biology and physiology of the NF-kB system, this volume also addresses the therapeutic targeting of NF-kB and its regulators. Thus, this volume is an important reading to both basic and translational scientists interested in different aspects of this highly versatile regulatory system.

About this edition

• Publisher: Springer
• Publication date: 2011
• ISBN 10: 3642160166
• ISBN 13: 9783642160165
• Binding: Hardcover
• Number of pages: 276
• Editor: Karin Michael