Multiple Sclerosis Therapeutics - Hardcover

9781841845258: Multiple Sclerosis Therapeutics

Hardcover

ISBN 10: 1841845256 ISBN 13: 9781841845258

Publisher: CRC Press, 2007

Since the publication of the previous edition of this volume, there has been substantial progress in a number of areas of multiple sclerosis (MS) research. Although immunosuppressive treatments continue to be developed and refined, more targeted immunomodulatory therapies are surfacing as we learn more about how the immune system works in health and disease.

Multiple Sclerosis Therapeutics, Third Edition provides a comprehensive review of clinical trial methodology and therapeutic modalities in MS. This edition reflects current understanding of the pathophysiology of the disease and includes popular and emerging treatments.

Topics include:

Biomarkers in MS
Pharmacogenomics
Emerging therapeutic modalities such as natalizumab, T-cell-based and B-cell-based therapies, cytokine/chemokine-based therapies, statins, and 4-aminopyridine
Neuroprotection
The use of OCT and MRI to guide disease therapy

Within the next several years, we will begin to discover the utility and the limitations of stem cells in the treatment of MS. It is likely that the next edition of this text will include clinical trial data that evaluate early attempts at nervous system regeneration in MS. Until that time occurs, this volume remains an essential resource for neurologists and anyone involved in the treatment of MS.

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Synopsis:

"Multiple Sclerosis Therapeutics, Third Edition" provides a comprehensive update of clinical trial methodology and current therapeutic modalities in multiple sclerosis. This new edition has been thoroughly revised and reorganized by the team of international contributors to reflect advances in understanding of the pathophysiology of the disease and to include new and emerging treatments. New chapters have been included on biomarkers in MS, pharmacogenomics, emerging therapeutic modalities (natalizumab, T-cell-based therapies, B-cell-based therapies, cytokine/chemokine-based therapies, statins, 4-aminopyridine), neuroprotection, and the use of OCT and MRI to guide disease therapy. The most comprehensive textbook on clinical trial methodology and treatment outcomes in multiple sclerosis, "Multiple Sclerosis Therapeutics" is a highly useful resource for neurologists and anyone involved in the treatment of multiple sclerosis.

About the Author:

Mellen Center for MS Treatment, Cleveland Clinic Foundation, Cleveland, OH, USA

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