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Seller: Books Puddle, New York, NY, U.S.A.
Condition: New. pp. 164.
Language: English
Published by Springer, Berlin / New York., 1999
ISBN 10: 3540650482 ISBN 13: 9783540650485
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Hardcover. Condition: Very Good. 8vo, hardcover. No dj. Vg+ condition. Prev. owner's name-labels very neatly removed from endpaper, small nick to endpaper corner; interior bright & clean, binding tight. vi, 148 p.
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Published by Springer Berlin Heidelberg, 2013
ISBN 10: 3662097117 ISBN 13: 9783662097113
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - It has been 12 years since the first proposal was made to sub divide mouse CD4 I T cell clones into Th I and Th2 subsets, based on their differences in cytokine production, and 7 years since the first clear demonstration of a similar dichotomy among human T cell clones. In the ensuing period, it has been realized that inappropriate development of Th I or Th2 responses are important features of many immunological and infectious dis eases. Perhaps the first group of diseases to be understood in terms of preferential Th subset activation were allergic diseases (see PARRONC'HI et aI. , this volume). Several of the major, co ordinately regulated, features of allergy, including IgE, eosino philia and mastocytosis, were found to be stimulated by the T- specific cytokines I L-4 and IL-5 and inhibited by the Th I cyto kine, IFN-. This suggested that the presence and severity of al lergic responses reflected the relative numbers of Th I and Th2 cells specific for the offending allergen. Similarly, the very dif ferent consequences of protective Th I and nonprotective Th2 responses to a number of intracellular pathogens have been re cognized for some time (see TRINCHIERI and SCOTI, and COFF MAN et aI. , this volume).
Language: English
Published by Springer Berlin Heidelberg Jan 2013, 2013
ISBN 10: 3662097117 ISBN 13: 9783662097113
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It has been 12 years since the first proposal was made to sub divide mouse CD4 I T cell clones into Th I and Th2 subsets, based on their differences in cytokine production, and 7 years since the first clear demonstration of a similar dichotomy among human T cell clones. In the ensuing period, it has been realized that inappropriate development of Th I or Th2 responses are important features of many immunological and infectious dis eases. Perhaps the first group of diseases to be understood in terms of preferential Th subset activation were allergic diseases (see PARRONC'HI et aI. , this volume). Several of the major, co ordinately regulated, features of allergy, including IgE, eosino philia and mastocytosis, were found to be stimulated by the T- specific cytokines I L-4 and IL-5 and inhibited by the Th I cyto kine, IFN-. This suggested that the presence and severity of al lergic responses reflected the relative numbers of Th I and Th2 cells specific for the offending allergen. Similarly, the very dif ferent consequences of protective Th I and nonprotective Th2 responses to a number of intracellular pathogens have been re cognized for some time (see TRINCHIERI and SCOTI, and COFF MAN et aI. , this volume). 164 pp. Englisch.
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Condition: New. PRINT ON DEMAND pp. 164.
Language: English
Published by Springer Berlin Heidelberg, 2013
ISBN 10: 3662097117 ISBN 13: 9783662097113
Seller: moluna, Greven, Germany
Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. List of Contents.- The Stability and Reversibility of Th1 and Th2 Populations.- T Helper Differentiation Proceeds Through Stat1-Dependent, Stat4-Dependent and Stat4-Independent Phases.- Redirecting Th2 Responses in Allergy.- Interleukin-12: Basic Principles.
Language: English
Published by Springer Berlin Heidelberg, Springer Berlin Heidelberg Jan 2013, 2013
ISBN 10: 3662097117 ISBN 13: 9783662097113
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germany
Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It has been 12 years since the first proposal was made to sub divide mouse CD4 I T cell clones into Th I and Th2 subsets, based on their differences in cytokine production, and 7 years since the first clear demonstration of a similar dichotomy among human T cell clones. In the ensuing period, it has been realized that inappropriate development of Th I or Th2 responses are important features of many immunological and infectious dis eases. Perhaps the first group of diseases to be understood in terms of preferential Th subset activation were allergic diseases (see PARRONC'HI et aI. , this volume). Several of the major, co ordinately regulated, features of allergy, including IgE, eosino philia and mastocytosis, were found to be stimulated by the T- specific cytokines I L-4 and IL-5 and inhibited by the Th I cyto kine, IFN-. This suggested that the presence and severity of al lergic responses reflected the relative numbers of Th I and Th2 cells specific for the offending allergen. Similarly, the very dif ferent consequences of protective Th I and nonprotective Th2 responses to a number of intracellular pathogens have been re cognized for some time (see TRINCHIERI and SCOTI, and COFF MAN et aI. , this volume).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 164 pp. Englisch.
Seller: preigu, Osnabrück, Germany
Taschenbuch. Condition: Neu. Redirection of Th1 and Th2 Responses | Robert L. Coffman (u. a.) | Taschenbuch | ix | Englisch | 2013 | Springer | EAN 9783662097113 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand.