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Taschenbuch. Condition: Neu. Neuware -'When you are doing something that is a brand new adventure, breaking new ground, whether it is something like a techno logical breakthrough or simply a way of living that is not what the community can help you with, there is always the danger of too much enthusiasm, of neglecting certain mechan ical details. Then you fall off. 'A danger path this is. ' When you follow the path of your desire and enthusiasm and emotion, keep your mind in control, and don't let it pull you compulsively into disaster. ' Joseph Campbell, The Power of Myth Through ten years of working with and observing scientists in the bio medical fields, I have found Joseph Campbell's words to be especially applicable to the scientist who decides to embark on an entrepreneurial journey. Joseph Campbell was not a student of entrepreneurship. His scholarship was contained in a series of comprehensive studies of mythology, the captivating stories of mankind's search over the ages for truth, meaning and significance. Still, his advice here contains many of the essential ingredients of successful science-based venturing: the charting of new ground socially, technological breakthroughs, enthusiasm and emotion balanced by careful reasoning, and finally, awareness of the danger of neglecting details. Coming from such a different philosophical and occupational culture into entrepreneurship and business, the scientist faces extraordinary challenges although the rewards of putting together a successful company can be equally satisfying.

Taschenbuch. Condition: Neu. Neuware -PRINCIPLES OF PERINATAL-NEONATAL METABOLISM, 2ND EDITION assembles a stellar international group of contributors to examine the various aspects of metabolism in the human adult during pregnancy, in the fetus, and in the newborn. New to the 2nd edition is expanded coverage of methodologies using molecular biology technqiues, central nervous system metabolism, and a new section on organ-specific metabolism that is organized by organ-system. For neonatalogists, perinatalogists, maternal-fetal medicine specialists.

Taschenbuch. Condition: Neu. Neuware -1 Gas Chromatography-Mass Spectrometry of Prostaglandins.- I. Introduction.- II. Mass Spectrometry Systems for Prostaglandin Analysis.- III. Methods of Extraction and Chromatography.- IV. Biological Applications.- V. References.- Note Added in Proof.- 2 Prostaglandin Biosynthesis and Metabolism as Measured by Radioimmunoassay.- I. Introduction.- II. Serological Specificities of the Prostaglandin Immune Systems.- III. Prostaglandin Synthetase.- IV. Prostaglandin E 9-Ketoreductases.- V. 15-Hydroxyprostaglandin Dehydrogenases.- VI. Prostaglandin 13-Reductase.- VII. PGE Dehydrase, PGA Isomerase, and PGC Isomerase.- VIII. Regulation of PGE and PGF Levels.- IX. References.- Note Added in Proof.- 3 The Endocrine System: Interaction of Prostaglandins with Adenylyl Cyclase-Cyclic AMP Systems.- I. Introduction.- II. Thyroid.- III. Pituitary.- IV. Pancreas.- V. Adrenal.- VI. Ovaries.- VII. References.- 4 Induction of Labor with Prostaglandins.- I. Historical Background.- II. Induction of Labor with Intravenous Prostaglandins.- III. Other Routes of Administration.- IV. Conclusions.- V. References.- 5 Cardiovascular Responses to the Prostaglandin Precursors.- I. Introduction.- II. Blood Pressure.- III. Cardiac Effects.- IV. Renal Circulation.- V. Pulmonary Circulation.- VI. Other Regional Circulations.- VII. Platelets 141 VIII Summary.- IX. References.- 6 Role of Prostaglandins in Fever and Temperature Regulation.- I. Introduction.- A. Temperature Regulation B. Fever 148.- II. Role of PGs in Fever.- III. PG Synthesis in Brain during Fever.- IV. Difficulties with the PG Hypothesis.- V. PGs in Normal Temperature Regulation.- VI. Summary of the Existing Evidence.- VII. Addendum.- VIII. References.- 7 Prostaglandins and the Lung.- I. Introduction.- II. Prostaglandin Content andSynthesis in the Lung.- III. Catabolism and Uptake of Prostaglandins in the Lung.- IV. Release of Prostaglandins from the Lung.- V. Bronchopulmonary Effects of Prostaglandins.- VII. Summary and Conclusions.- VIII. References.- Note Added in Proof.- 8 Prostaglandins and the Digestive System.- I. Introduction.- II. Salivary Glands.- III. Esophagus.- IV. Stomach.- VI. Bile and Pancreatic Secretion.- VII. Cytoprotection by Prostaglandins.- VIII. References.- 9 Prostaglandins and Renal Function, or 'A Trip down the Rabbit Hole'.- I. Introduction.- II. Prostaglandin Synthesis and Metabolism.- III. Role of Prostaglandins in the Control of Renal Blood Flow.- IV. Role of Prostaglandins in Salt and Water Homeostasis.- V. Conclusion.- VI. References.- Note Added in Proof.- 10 Prostaglandins and Cancer.- I. Introduction.- II. Prostaglandin Synthesis by Tumors and Its Effects on Tumor Cell Replication.- III. Prostaglandins, Bone Resorption, and Hypercalcemia.- IV. Conclusions.- V. References.

Taschenbuch. Condition: Neu. Neuware -This volume records the papers presented in Chieti, Italy, at the 1991 meeting of the International Society for Arterial Chemoreception (ISAC). This was the eleventh of a series of assemblies held since 1959. This field of research, which examines the critical function and mechanisms of O and pHIPC0 sensitive cells in 2 2 the body, is unique in that it encompasses diverse biological and medical areas. The reader of this book will note chapters concerning modem techniques like in situ hybridization; analysis of cell membrane channels and intracellular ion movements; immunohistochemistry of peptides, hormones, and the corresponding receptors of chemoreceptor cells; and systemic analysis of reflex pathways involving chemoreceptor cells and their meaning in health and disease. This broad spectrum will appeal to readers interested in the chemoreceptor field, as well as young scientists seeking a scientific field where not only structural analysis but also a sense for functional connections is required. In recognition of the importance of the contribution of a new scientific generation to this field, ISAC awarded the prestigious F. de Castro-C. Heymans E. Neil prize to A. G6rlach, a young scientist. Also at this meeting, the Ferdinando Data Foundation Award, for helping scientists from non-developed countries to pursue their interest in chemoreception, was initiated. ISAC held plenary lectures in honor of C. Eyzaguirre and R. Forster, both of whom have contributed greatly to research in the chemoreceptor field.

Taschenbuch. Condition: Neu. Neuware -since the earliest results on the linkage between ras activation and cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras-related genes in membrane trafficking, cell proliferation, differentiation and cancer. These advances led to the development of new strategies for the diagnosis, prognosis and prevention of cancer. Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal point upon which attempts to intervene in the process of carcinogenesis will be concentrated. The present volume contains the contributions to the NATO Advanced Research Workshop on the 'The Superfamily of ras-Related Genes' held in Agia Pelagia, Heraklion, Crete, Greece, May 1991. At this meeting the leading researchers in this field carne together to discuss the most recent progress in analysis of biological function of the ras-related genes. As an organizer I feel that the Workshop was a success, and would like to thank all the participants and the contributors to this volume. I thank the NATO Scientific Affairs Division, Brussels, the Greek Ministry of Industry, Energy and Technology, the International Center for Cancer Research, the National Hellenic Research Foundation and the Medical School, University of Crete for sponsoring the Meeting.

Taschenbuch. Condition: Neu. Neuware -It is a pleasure to present the book, Evaluation and Treatment of Obesity, for reference and textbook use. The text is an outgrowth of the Obesity Weight Control Track of the 1982 La Crosse Health and Sports Science Symposium, sponsored annually by the La Crosse Exercise Program, Uni versity of Wisconsin-La Crosse. With versatile faculty, topics, and attend ing professionals, the Obesity-Weight Control Track stimulated an effort to produce interdisciplinary resources on obesity. Out of this effort, three books have been compiled and edited. This book, Evaluation and Treatment of Obesity, introduces an interdis ciplinary, practical approach to obesity management. The other two books, Nutrition and Exercise in Obesity Management and Behavioral Management of Obesity, expand on the basic theories introduced in this book, providing in-depth information of value to the practicing profes sional. These three books apply the latest information from the fields of medicine, nutrition, exercise, and psychology to the problem of obesity. The information is intended to guide health professionals in the inter disciplinary management of obesity. In 1983 the Obesity-Weight Control Track focused on controversial issues of theoretical and practical concern. The speakers from this track contributed their expertise to the compilation of two additional books. Thus, Trends and Controversies in Obesity Research and Innovation in Obesity Program Development will complete the series. Consider the five volumes a consolidated, comprehensive reference related to the growing, interdisciplinary field of weight control.

Taschenbuch. Condition: Neu. Neuware -This book is about compressing data to make digital systems work more effi ciently. According to the dictionary, when something is compressed, it is con densed, squeezed, constricted, or pressed together to fit into less space. Air is compressed for a variety of useful purposes. Businesses are downsized to make them more efficient. We pack our daily schedules tighter and tighter to accomplish more. Who has not crushed an empty soda can for recycling Many different things can be compressed, including the data in computers, communications links, consumer-electronics gear, and all sizes and shapes of digital systems. Are you curious about how data compression squeezes the 'air' out of digital bits Would you like to know where it is used and, increasingly, why the marketplace demands it be used Would you like to learn the right way to build data compres sion into your products Then, this book is for you. This exciting technology and its importance for current and future digital systems are explained in easy to understand terms. No previous knowledge of data compression is required because the necessary technical background is carefully developed. Neither is an extensive understanding of mathematics be cause there are few equations and important ideas are graphically illustrated. If you read any of the popular or professional monthly magazines that cover the latest advances in digital systems, your background is adequate. If you understand this preface, you are ready to tackle this book.

Taschenbuch. Condition: Neu. Neuware -Many chemists and biochemists require to know the ionization constants of organic acids and bases. This is evident from the Science Citation Index which lists The Determination of Ionization Constants by A. Albert and E. P. Serjeant (1971) as one of the most widely quoted books in the chemical literature. Although, ultimately, there is no satisfactory alternative to experimental measurement, it is not always convenient or practicable to make the necessary measure ments and calculations. Moreover, the massive pK. compilations currently available provide values for only a small fraction of known or possible acids or bases. For example, the compilations listed in Section 1. 3 give pK. data for some 6 000--8 000 acids, whereas if the conservative estimate is made that there are one hundred different substituent groups available to substitute in the benzene ring of benzoic acid, approximately five million tri-substituted benzoic acids are theoretically possible. Thus we have long felt that it is useful to consider methods by which a pK. value might be predicted as an interim value to within several tenths of a pH unit using arguments based on linear free energy relationships, by analogy, by extrapolation, by interpolation from existing data, or in some other way. This degree of precision may be adequate for many purposes such as the recording of spectra of pure species (as anion, neutral molecule or cation), for selection of conditions favourable to solvent extraction, and for the interpretation of pH-profiles for organic reactions.

Taschenbuch. Condition: Neu. Neuware - Many chemists and biochemists require to know the ionization constants of organic acids and bases. This is evident from the Science Citation Index which lists The Determination of Ionization Constants by A. Albert and E. P. Serjeant (1971) as one of the most widely quoted books in the chemical literature. Although, ultimately, there is no satisfactory alternative to experimental measurement, it is not always convenient or practicable to make the necessary measure ments and calculations. Moreover, the massive pK. compilations currently available provide values for only a small fraction of known or possible acids or bases. For example, the compilations listed in Section 1. 3 give pK. data for some 6 000--8 000 acids, whereas if the conservative estimate is made that there are one hundred different substituent groups available to substitute in the benzene ring of benzoic acid, approximately five million tri-substituted benzoic acids are theoretically possible. Thus we have long felt that it is useful to consider methods by which a pK. value might be predicted as an interim value to within several tenths of a pH unit using arguments based on linear free energy relationships, by analogy, by extrapolation, by interpolation from existing data, or in some other way. This degree of precision may be adequate for many purposes such as the recording of spectra of pure species (as anion, neutral molecule or cation), for selection of conditions favourable to solvent extraction, and for the interpretation of pH-profiles for organic reactions.

Taschenbuch. Condition: Neu. Neuware - It is a pleasure to present the book, Evaluation and Treatment of Obesity, for reference and textbook use. The text is an outgrowth of the Obesity Weight Control Track of the 1982 La Crosse Health and Sports Science Symposium, sponsored annually by the La Crosse Exercise Program, Uni versity of Wisconsin-La Crosse. With versatile faculty, topics, and attend ing professionals, the Obesity-Weight Control Track stimulated an effort to produce interdisciplinary resources on obesity. Out of this effort, three books have been compiled and edited. This book, Evaluation and Treatment of Obesity, introduces an interdis ciplinary, practical approach to obesity management. The other two books, Nutrition and Exercise in Obesity Management and Behavioral Management of Obesity, expand on the basic theories introduced in this book, providing in-depth information of value to the practicing profes sional. These three books apply the latest information from the fields of medicine, nutrition, exercise, and psychology to the problem of obesity. The information is intended to guide health professionals in the inter disciplinary management of obesity. In 1983 the Obesity-Weight Control Track focused on controversial issues of theoretical and practical concern. The speakers from this track contributed their expertise to the compilation of two additional books. Thus, Trends and Controversies in Obesity Research and Innovation in Obesity Program Development will complete the series. Consider the five volumes a consolidated, comprehensive reference related to the growing, interdisciplinary field of weight control.

Taschenbuch. Condition: Neu. Neuware - 'When you are doing something that is a brand new adventure, breaking new ground, whether it is something like a techno logical breakthrough or simply a way of living that is not what the community can help you with, there is always the danger of too much enthusiasm, of neglecting certain mechan ical details. Then you fall off. 'A danger path this is. ' When you follow the path of your desire and enthusiasm and emotion, keep your mind in control, and don't let it pull you compulsively into disaster. ' Joseph Campbell, The Power of Myth Through ten years of working with and observing scientists in the bio medical fields, I have found Joseph Campbell's words to be especially applicable to the scientist who decides to embark on an entrepreneurial journey. Joseph Campbell was not a student of entrepreneurship. His scholarship was contained in a series of comprehensive studies of mythology, the captivating stories of mankind's search over the ages for truth, meaning and significance. Still, his advice here contains many of the essential ingredients of successful science-based venturing: the charting of new ground socially, technological breakthroughs, enthusiasm and emotion balanced by careful reasoning, and finally, awareness of the danger of neglecting details. Coming from such a different philosophical and occupational culture into entrepreneurship and business, the scientist faces extraordinary challenges although the rewards of putting together a successful company can be equally satisfying.

Taschenbuch. Condition: Neu. Neuware -Flavour is an important sensory aspect of the overall acceptability of meat products. Whether we accept or reject a food depends primarily on its flavour. Both desirable and undesirable flavour effects are contemplated. Furthermore, threshold values of different flavour-active compounds have an important effect on the cumulative sensory properties of all foods. Meat from different species constitutes a major source of protein for most people. Although raw meat has little flavour and only a blood-like taste, it is a rich reservoir of non-volatile compounds with taste-tactile properties as well as flavour enhancers and aroma precursors. Non-vola tile water-soluble precursors and lipids influence the flavour of meat from different species. In addition, mode of heat processing and the nature of additives used may have a profound effect on the flavour of prepared meats. This book reports the latest advancements in meat flavour research. Following a brief overview, chapters 2 to 5 discuss flavours from different species of meat, namely beef, pork, poultry and mutton. In chapters 6 to 12 the role of meat constituents and processing on flavour are described. The final section of the book (chapters 13 to 15) summarizes analytical methodologies for assessing the flavour quality of meats. I wish to thank all the authors for their cooperative efforts and com mendable contributions which have made this publication possible.

Taschenbuch. Condition: Neu. Neuware - since the earliest results on the linkage between ras activation and cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras-related genes in membrane trafficking, cell proliferation, differentiation and cancer. These advances led to the development of new strategies for the diagnosis, prognosis and prevention of cancer. Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal point upon which attempts to intervene in the process of carcinogenesis will be concentrated. The present volume contains the contributions to the NATO Advanced Research Workshop on the 'The Superfamily of ras-Related Genes' held in Agia Pelagia, Heraklion, Crete, Greece, May 1991. At this meeting the leading researchers in this field carne together to discuss the most recent progress in analysis of biological function of the ras-related genes. As an organizer I feel that the Workshop was a success, and would like to thank all the participants and the contributors to this volume. I thank the NATO Scientific Affairs Division, Brussels, the Greek Ministry of Industry, Energy and Technology, the International Center for Cancer Research, the National Hellenic Research Foundation and the Medical School, University of Crete for sponsoring the Meeting.

Taschenbuch. Condition: Neu. Neuware - 1 Gas Chromatography-Mass Spectrometry of Prostaglandins.- I. Introduction.- II. Mass Spectrometry Systems for Prostaglandin Analysis.- III. Methods of Extraction and Chromatography.- IV. Biological Applications.- V. References.- Note Added in Proof.- 2 Prostaglandin Biosynthesis and Metabolism as Measured by Radioimmunoassay.- I. Introduction.- II. Serological Specificities of the Prostaglandin Immune Systems.- III. Prostaglandin Synthetase.- IV. Prostaglandin E 9-Ketoreductases.- V. 15-Hydroxyprostaglandin Dehydrogenases.- VI. Prostaglandin 13-Reductase.- VII. PGE Dehydrase, PGA Isomerase, and PGC Isomerase.- VIII. Regulation of PGE and PGF Levels.- IX. References.- Note Added in Proof.- 3 The Endocrine System: Interaction of Prostaglandins with Adenylyl Cyclase-Cyclic AMP Systems.- I. Introduction.- II. Thyroid.- III. Pituitary.- IV. Pancreas.- V. Adrenal.- VI. Ovaries.- VII. References.- 4 Induction of Labor with Prostaglandins.- I. Historical Background.- II. Induction of Labor with Intravenous Prostaglandins.- III. Other Routes of Administration.- IV. Conclusions.- V. References.- 5 Cardiovascular Responses to the Prostaglandin Precursors.- I. Introduction.- II. Blood Pressure.- III. Cardiac Effects.- IV. Renal Circulation.- V. Pulmonary Circulation.- VI. Other Regional Circulations.- VII. Platelets 141 VIII Summary.- IX. References.- 6 Role of Prostaglandins in Fever and Temperature Regulation.- I. Introduction.- A. Temperature Regulation B. Fever 148.- II. Role of PGs in Fever.- III. PG Synthesis in Brain during Fever.- IV. Difficulties with the PG Hypothesis.- V. PGs in Normal Temperature Regulation.- VI. Summary of the Existing Evidence.- VII. Addendum.- VIII. References.- 7 Prostaglandins and the Lung.- I. Introduction.- II. Prostaglandin Content andSynthesis in the Lung.- III. Catabolism and Uptake of Prostaglandins in the Lung.- IV. Release of Prostaglandins from the Lung.- V. Bronchopulmonary Effects of Prostaglandins.- VII. Summary and Conclusions.- VIII. References.- Note Added in Proof.- 8 Prostaglandins and the Digestive System.- I. Introduction.- II. Salivary Glands.- III. Esophagus.- IV. Stomach.- VI. Bile and Pancreatic Secretion.- VII. Cytoprotection by Prostaglandins.- VIII. References.- 9 Prostaglandins and Renal Function, or 'A Trip down the Rabbit Hole'.- I. Introduction.- II. Prostaglandin Synthesis and Metabolism.- III. Role of Prostaglandins in the Control of Renal Blood Flow.- IV. Role of Prostaglandins in Salt and Water Homeostasis.- V. Conclusion.- VI. References.- Note Added in Proof.- 10 Prostaglandins and Cancer.- I. Introduction.- II. Prostaglandin Synthesis by Tumors and Its Effects on Tumor Cell Replication.- III. Prostaglandins, Bone Resorption, and Hypercalcemia.- IV. Conclusions.- V. References.

Taschenbuch. Condition: Neu. Neuware - This volume records the papers presented in Chieti, Italy, at the 1991 meeting of the International Society for Arterial Chemoreception (ISAC). This was the eleventh of a series of assemblies held since 1959. This field of research, which examines the critical function and mechanisms of O and pHIPC0 sensitive cells in 2 2 the body, is unique in that it encompasses diverse biological and medical areas. The reader of this book will note chapters concerning modem techniques like in situ hybridization; analysis of cell membrane channels and intracellular ion movements; immunohistochemistry of peptides, hormones, and the corresponding receptors of chemoreceptor cells; and systemic analysis of reflex pathways involving chemoreceptor cells and their meaning in health and disease. This broad spectrum will appeal to readers interested in the chemoreceptor field, as well as young scientists seeking a scientific field where not only structural analysis but also a sense for functional connections is required. In recognition of the importance of the contribution of a new scientific generation to this field, ISAC awarded the prestigious F. de Castro-C. Heymans E. Neil prize to A. G6rlach, a young scientist. Also at this meeting, the Ferdinando Data Foundation Award, for helping scientists from non-developed countries to pursue their interest in chemoreception, was initiated. ISAC held plenary lectures in honor of C. Eyzaguirre and R. Forster, both of whom have contributed greatly to research in the chemoreceptor field.

Taschenbuch. Condition: Neu. Neuware - This book is about compressing data to make digital systems work more effi ciently. According to the dictionary, when something is compressed, it is con densed, squeezed, constricted, or pressed together to fit into less space. Air is compressed for a variety of useful purposes. Businesses are downsized to make them more efficient. We pack our daily schedules tighter and tighter to accomplish more. Who has not crushed an empty soda can for recycling Many different things can be compressed, including the data in computers, communications links, consumer-electronics gear, and all sizes and shapes of digital systems. Are you curious about how data compression squeezes the 'air' out of digital bits Would you like to know where it is used and, increasingly, why the marketplace demands it be used Would you like to learn the right way to build data compres sion into your products Then, this book is for you. This exciting technology and its importance for current and future digital systems are explained in easy to understand terms. No previous knowledge of data compression is required because the necessary technical background is carefully developed. Neither is an extensive understanding of mathematics be cause there are few equations and important ideas are graphically illustrated. If you read any of the popular or professional monthly magazines that cover the latest advances in digital systems, your background is adequate. If you understand this preface, you are ready to tackle this book.

Taschenbuch. Condition: Neu. Neuware - The need for writing a monograph on polymer blends and composites became apparent during presentation of material on this subject to our advanced polymers class. Although the flood of important research in this area in the past decade has resulted in many symposia, edited collections of papers, reviews, contributions to scientific journals, and patents, apparently no organized presentation in book form has been forthcoming. In a closely connected way, another strong impetus for writing this monograph arose out of our research programs in the Materials Research Center at Lehigh University. As part of this effort, we had naturally compiled hundreds of references and become acquainted with many leaders in the field of blend and composite research. Perhaps the most important concept stressed over and over again is that engineering materials are useful because of their complexity, not in spite of it. Blends and composites are toughened because many modes of resistance to failure are available. Although such multimechanism processes are diffi cult to describe with a unified theory. we have presented available develop ments in juxtaposition with the experimental portions. The arguments somewhat resemble the classical discussion of resonance in organic chemistry, where molecular structures increase in stability as more electronic configura tions become available.

Taschenbuch. Condition: Neu. Neuware - Highlighting examples of positive, evidence based practice throughout, this book explores working with people with learning disabilities at all life stages. With contributions from people with learning disabilities and their families, its person-centred approach illustrates how policy can be translated into practice with life-changing consequences.

Taschenbuch. Condition: Neu. Neuware -Kosik writes that the history of a text is in a certain sense the history of its interpretations. In the fifteen years that have passed since the first (Czech) edition of his Dialectics of the Concrete, this book has been widely read and interpreted throughout Europe, in diverse centers of scholarship as well as in private studies. A faithful English language edition is long overdue. This publication of KosIk's work will surely provoke a range of new interpretations. For its theme is the characterization of science and of rationality in the context of the social roots of science and the social critique which an appropriately rational science should afford. Kosik's question is: How shall Karl Marx's understanding of science itself be understood And how can it be further developed In his treatment of the question of scientific rationality, KOSIK drives bluntly into the issues of gravest human concern, not the least of which is how to avoid the pseudo-concrete, the pseudo-scientific, the pseudo-rational, the pseudo historical. Starting with Marx's methodological approach, of 'ascending from the abstract to the concrete', KOSIK develops a critique of positivism, of phenomenalist empiricism, and of 'metaphysical' rationalism, counter posing them to 'dialectical rationalism'. He takes the category of the concrete in the dialectical sense of that which comes to be known by the active transformation of nature and society by human purposive activity.

Taschenbuch. Condition: Neu. Neuware - PRINCIPLES OF PERINATAL-NEONATAL METABOLISM, SECOND EDITION assembles a stellar international group of contributors to examine the various aspects of metabolism in the human adult during pregnancy, in the fetus, and in the newborn. Completely updated and revised with more than 17 new chapters, the book is divided into five sections: 1) Methodology and General Principles; 2) Maternal Metabolism During Pregnancy; 3) Fetal-Placental Metabolism; 4) Organ Specific Metabolism During the Perinatal Period; 5) Neonatal Metabolism. New to the second edition are discussions of methodologies using molecular biology technqiues, expanded coverage of central nervous system metabolism, and an entirely new section on organ-specific metabolism that is organized by organ-system. A must for every physician who cares for the pregnant patient and her child. From reviews of the critically acclaimed first edition: 'an incredible amount of information.of utmost value not only to the basic investigator but also to the clinician.' - JAMA 'a first-rate reference textbook that should be on the shelves of every institution that provides care for the pregnant women or her children' - NEJM 'I know of no other volume in which these important topics are integrated into a single text.I enthusiastically recommend it as a valuable reference to researchers, clinicians, fellows, and students.' - TEM.

Taschenbuch. Condition: Neu. Neuware - The goal of Advances in Clinical Child Psychology is to provide clinicians and researchers in clinical child psychology, child psychiatry, and relat- ed mental health disciplines with an annual compilation of statements that summarize the new data, concepts, and techniques that advance our ability to help troubled children. Looking forward, the series intends to highlight the emerging developments that will guide our field of inquiry and practice. Looking back, the dozen volumes in this series chronicle the changes in our attempts to understand and solve the psychological problems of children and adolescents. Each year, scholars are chosen whose recent work is on the leading edge of clinical child psychology and related disciplines. They are se- lected either because their own work offers potentially important new information or theoretical viewpoints or because they are especially well qualified to discuss critical topics in the field that are not identified with one particular research program.

Taschenbuch. Condition: Neu. Neuware -Mehr als die einfache Logik eines Frühmenschen brauchen Sie nicht, um die Grundzüge der Mathematik zu verstehen. Denn Sie treffen in diesem Buch viele einfache, fast gefühlsmäßig zu erfassende mathematische Prinzipien des täglichen Lebens. Deswegen kann der Autor bei seinem Versuch, die Mathematik 'begreiflich' zu machen, in die Steinzeit zurückgehen - genauer gesagt: etwa in die Jungsteinzeit, 10.000 Jahre vor unserer Zeitrechnung. Ackerbau und Viehzucht hatten schon begonnen. Dort treffen Sie Eddi Einstein, den Denker und Rudi Radlos, den Erfinder - die Hauptakteure. Ein dritter Geselle ist Siggi Spökenkieker, der Druide und Seher. Siggi ist mit der Gabe der Präkognition gesegnet. So können wir Eddi, den Denker, mit Erkenntnissen ausstatten, die erst Jahrtausende später von bedeutenden Philosophen und Mathematikern erlangt worden waren. Die wahre Meisterin dieser Wissenschaftsdisziplin ist jedoch Wilhelmine Wicca. Sie war so klug wie die drei Kerle zusammen. Deshalb galt sie auch als Hexe - was damals ein Ehrentitel war - und als weise Frau. 434 pp. Deutsch.

Taschenbuch. Condition: Neu. Neuware -Mehr als die einfache Logik eines Frühmenschen brauchen Sie nicht, um die Grundzüge der Mathematik zu verstehen. Denn Sie treffen in diesem Buch viele einfache, fast gefühlsmäßig zu erfassende mathematische Prinzipien des täglichen Lebens. Deswegen kann der Autor bei seinem Versuch, die Mathematik 'begreiflich' zu machen, in die Steinzeit zurückgehen - genauer gesagt: etwa in die Jungsteinzeit, 10.000 Jahre vor unserer Zeitrechnung. Ackerbau und Viehzucht hatten schon begonnen. Dort treffen Sie Eddi Einstein, den Denker und Rudi Radlos, den Erfinder - die Hauptakteure. Ein dritter Geselle ist Siggi Spökenkieker, der Druide und Seher. Siggi ist mit der Gabe der Präkognition gesegnet. So können wir Eddi, den Denker, mit Erkenntnissen ausstatten, die erst Jahrtausende später von bedeutenden Philosophen und Mathematikern erlangt worden waren. Die wahre Meisterin dieser Wissenschaftsdisziplin ist jedoch Wilhelmine Wicca. Sie war so klug wie die drei Kerle zusammen. Deshalb galt sie auch als Hexe - was damals ein Ehrentitel war - und als weise Frau. 434 pp. Deutsch.

Taschenbuch. Condition: Neu. Neuware - Judging from the articles published in Biochemistry, magnetic resonance techniques (NMR and ESR) are now among the most popular methods in biochemical research. The series Biological Magnetic Resonance, the fifth volume of which we are proudly presenting, is intended to provide authori tative coverage of topics of current interest. Previous volumes have covered a number of aspects in a thorough and pedagogical fashion rarely found in other publications in this field. Continuing to fulfill the mission of the series, this volume presents a chapter by Baxter, Mackenzie, and Scott on the applications of carbon-13 NMR spectroscopy in investigations of methabolic pathways in vivo. Blom berg and Ruterjans give a comprehensive summary of the use of nitrogen-15 NMR in studies of systems of biological interest. Phosphorus-3I NMR investigations of enzyme systems are described by Rao. Tsai and Bruzik outline the principles of and summarize the state-of-the-art advances in the 18 use of oxygen isotopes e 70 and 0) in phosphorus-3I and oxygen-17 NMR studies of biophosphates. Lipid-protein interactions as reflected in ESR and NMR data are discussed by Devaux. We wish to thank the authors for their cooperation in maintaining the and continued high standards of the series.

Taschenbuch. Condition: Neu. Neuware - The American Institute for Cancer Research (AICR) sponsored its second annual conference on nutrition and cancer. The theme was 'Exercise, Calories, Fat, and Cancer' and the conference was held September 4-5, 1991 at the Ritz Carlton Hotel in Pentagon City, Virginia. This proceedings volume contains chapters from the platform presentations and abstracts from each poster presentation. Relationships among physical activity, calorie consumption, energy expenditure, dietary fat, and cancer are described in the context of epidemiologic, animal, and in vitro studies. Dietary recommendations to lower cancer risk are based on expanding evidence relating nutrition and cancer. Identification of the precise dietary contribution to disease is complicated by the concurrent genetic and environmental contributions, in addition to the inherent difficulties in gathering and interpreting epidemiologic data. Individual variations in cancer risk are the result of differences in genetic and environmental factors including sources and amounts of calories consumed, metabolism, and energy expenditure. Human and animal studies describing independent and combined influences of exercise, calorie restriction, and dietary fat on carcinogenesis are reported in this volume.

Taschenbuch. Condition: Neu. Neuware - This long-awaited second edition has been thoroughly updated and revised by Dr. Michael Salcman with the assistance of Edward R. Laws, MD, Roberto Heros, MD, and Volker Sonntag, MD, yet still preserves the user-friendly aspects of the original book: brevity and ease of practical application in the operating room environment.

Taschenbuch. Condition: Neu. Neuware - All the papers in this volume were presented at a conference on Transportation and Urban Life, held in Munich during the third week of September, 1975. The conference was sponsored by the Special Programme Panels on Systems Science and Human Factors of the Science Committee of the North Atlantic Treaty Organisation. The distinguishing characteristic of the conference and of this volume lies in the combination of systems science and human factors contributions in the field of urban transportation. The initiative for attempting such a synthesis came from the sponsors. It is increasingly realised that the complexity of contemporary problems which applied scientists are being asked to solve is such that the coordinated efforts of several disciplines are needed to solve them. The brief which we formulated for the conference and distribu ted in our international call for papers was as follows: 'The conference is intended to highlight significant psycho logical, SOCiological and economic aspects of transportation and urban life and to present new techniques which can be applied to these aspects and their interfaces'. Papers were invited in four topic areas: Communities (transportation problems in relation to social needs, residential planning, industry and c0l1lITlerce) ; Cities and large urban areas (the econOlnic environment, material fl~l, resources); Regional development and transportation (administration and management at the project and multiprogramme level); and Quality of life and transportation (noise, visual intrusion, severance, air pollution).

Taschenbuch. Condition: Neu. Neuware - Microcloning of Microdissected Chromosome Fragments.- Transient Expression of Cloned Genes in Mammalian Cells.- Transposable Elements in Archaebacteria.- The Application of Restriction Fragment Length Polymorphism to Plant Breeding.- Antibodies Agains Synthetic Peptides.- Wheat -Amylase Genes: Cloning of a Developmentally Regulated Gene Family.- Yeast DNA Replication.- Chromosome Engineering in Wheat Breeding and Its Implications for Molecular Genetic Engineering.- Bovine Papillomavirus Shuttle Vectors.- Chemical Synthesis of Oligodeoxyribonucleotides: A Simplified Procedure.

Taschenbuch. Condition: Neu. Neuware - Evolutionary Biology, of which this is the eighteenth volume, con tinues to offer its readers a wide range of original articles, reviews, and commentaries on evolution, in the bro~dest sense of that term. The topics of the reviews range from anthropology and behavior to molecular biology and systematics. In recent volumes, a broad spectrum of articles have appeared on such subjects as natural selection among replicating molecules in vitro, mate recognition and the reproductive behavior of Drosophila, molecular systematics ofCrocodilia, evolution of the monocotyledons, and the com munication network made possible among even distantly related genera of bacteria by plasmids and other transposable elements. Articles such as these, often too long for standard journals , are the stuff of Evolutionary Biology. The editors continue to solicit manuscripts on an international scale in an effort to see that everyone of the many facets of biological evolution is covered. Manuscripts should be sent to anyone of the following: Max K. Hecht, Department of Biology, Queens College of the City University of New York, Flushing, New York 11367; Bruce Wallace, Department of Biology, Virginia Polytechnic Institute and State University, Blacks burg, Virginia 24061; Ghillian T. Prance, New York Botanical Garden, Bronx, New York 10458.

Taschenbuch. Condition: Neu. Neuware - Genomic Footprinting.- Theoretical and Computer Analysis of Protein Primary Sequences: Structure Comparison and Prediction.- Affinity Chromatography of Sequence-Specific DNA-Binding Proteins.- Applications of the Firefly Luciferase as a Reporter Gene.- Fluorescence-Based Automated DNA Sequence Analysis.- Phosphorothioate-Based Oligonucleotide-Directed Mutagenesis.- Design and Use of Agrobacterium Transformation Vectors.- Cell Commitment and Determination in Plants.- Plasmids Derived from Epstein-Barr Virus: Mechanisms of Plasmid Maintenance and Applications in Molecular Biology.- Chromosome Jumping: A Long Range Cloning Technique.- Isolation of Intact mRNA and Construction of Full-Length cDNA Libraries: Use of a New Vector, gt22, and Primer-Adapters for Directional cDNA Cloning.- The Use of Transgenic Animal Techniques for Livestock Improvement.- Plant Reporter Genes: The Gus Gene Fusion System.- Structure of the Genes Encoding Proteins Involved in Blood Clotting.