springer new york mai 2014 (163 results)

Taschenbuch. Condition: Neu. Neuware -To the naked eye, the most evident defining feature of the planets is their motion across the night sky. It was this motion that allowed ancient civilizations to single them out as different from fixed stars. żThe Observerżs Guide to Planetary Motionż takes each planet and its moons (if it has them) in turn and describes how the geometry of the Solar System gives rise to its observed motions.Although the motions of the planets may be described as simple elliptical orbits around the Sun, we have to observe them from a particular vantage point: the Earth, which spins daily on its axis and circles around the Sun each year. The motions of the planets as observed relative to this spinning observatory take on more complicated patterns. Periodically, objects become prominent in the night sky for a few weeks or months, while at other times they pass too close to the Sun to be observed. żThe Observerżs Guide to Planetary Motionż provides accurate tables of the best time for observing each planet, together with other notable events in their orbits, helping amateur astronomers plan when and what to observe. Uniquely each of the chapters includes extensive explanatory text, relating the events listed to the physical geometry of the Solar System.Along the way, many questions are answered: Why does Mars take over two years between apparitions (the times when it is visible from Earth) in the night sky, while Uranus and Neptune take almost exactly a year Why do planets appear higher in the night sky when theyżre visible in the winter months Why do Saturnżs rings appear to open and close every 15 years This book places seemingly disparate astronomical events into an understandable three-dimensional structure, enabling an appreciation that, for example, very good apparitions of Mars come around roughly every 15 years and that those in 2018 and 2035 will be nearly as good as that seen in 2003.Events are listed for the time period2010-2030 and in the case of rarer events (such as eclipses and apparitions of Mars) even longer time periods are covered. A short closing chapter describes the seasonal appearance of deep sky objects, which follow an annual cycle as a result of Earthżs orbital motion around the Sun.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.

Taschenbuch. Condition: Neu. Neuware -Case Studies in Service Innovation provides the reader fresh insight into how innovation occurs in practice, and stimulates learning from one context to another. The volume brings together contributions from researchers and practitioners in a celebration of achievements with the intention of adding to the wider understanding of how service innovation develops. Each case presents a brief description of the context in which the innovation occurred, the opportunity that led to the innovation and an overview of the innovation itself, also addressing how success was measured, what success has been achieved to date and providing links to further information. The book is organized around five major themes, each reflecting recognized sources of service innovation: Business Model Innovation: new ways of creating, delivering or capturing economic, social, environmental and other types of value; The Organization in its Environment: an organization engaging beyond its own boundaries, with public private partnerships, sourcing knowledge externally, innovation networks, and open or distributed innovation; Innovation Management within an Organization: an organization actively encouraging innovation within its own boundaries using project teams, internal governance of innovation, and methods or tools that stimulate innovation; Process Innovation: changes in service design and delivery processes, such as consumer led innovation or consumers as part of the innovation process, service operations management, and educational processes; Technology Innovation: the use of technology, including ICT enabled innovation, ICTs that are themselves innovative and support the delivery of new services, new ICT services, new ways of delivering services associated with ICT products, and technology other than ICT. The final part of the book is given to four extended cases allowing for a more in-depth treatment of innovation within a complex service system. The extended cases also illustrate two important and growing trends, firstly the need for, and benefits of, a more customer centric approach to service innovation and secondly the need for better understanding of public services and the role of public-private partnerships in identifying and achieving innovation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.

Taschenbuch. Condition: Neu. Neuware -With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals specific to the metabolomics community. This book will be particularly useful for post-graduate students and post-doctoral researchers using this pioneering technique of network-based correlation analysis. The approach can be adapted to the analysis of any large scale metabolic profiling experiment to answer a range of biological questions in a range of species or for a range of diseases.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 68 pp. Englisch.

Taschenbuch. Condition: Neu. Neuware -This SpringerBrief summarizes a full-scale, reduced commodity fire testing comparison of cartoned Lithium ion batteries and FM Global standard commodities in a rack storage configuration, as reported by FM Global. Tests evaluate the flammability characteristics of the materials and the effectiveness of ceiling level only sprinkler protection. The testing methods, discussed in depth, are scaled down from standard commodity classification testing due to the inordinate costs of Li-ion batteries. Small format Li-ion battery commodities represent both commercially available battery formats and Li-ion battery containing devices. The selected Li-ion battery types are individual 18650 format cylindrical cells, power tool packs comprised of 18650 format cells and polymer cells. The selected comparison commodities are the FM Global standard Class 2 and Cartoned Unexpanded Plastic (CUP). The results offer insight into the combined effects of different storage heights, ceiling height, protection system design, battery density, state of charge and battery type. Flammability of Cartoned Lithium Ion Batteries is intended for practitioners as a tool for analyzing commodity testing methods and providing data about potential hazards. Researchers working in a related field will also find the book valuable.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 52 pp. Englisch.

Taschenbuch. Condition: Neu. Neuware -This SpringerBrief explores the evacuation characteristics of children and their self-preservation capability during fire situations. An international survey among teachers from day-care centers and experts in child development indicates an age-limit at which pre-school children may be considered capable of evacuating a location without direct intervention by an instructor.The survey examines the ability of children to understand and follow simple instructions, walk on horizontal surfaces without physical support, and walk down stairs. It also studies how fire safety installations and fire drills differ between countries. A literature review and a presentation of the method applied are included.This data can be applied to evacuation procedures, building codes, and fire regulations. Determining Self-Preservation Capability in Pre-School Children is intended for practitioners as a tool for analyzing evacuation safety issues and developing methods removing potential hazards. Researchers working in a related field will also find the book valuable.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 60 pp. Englisch.

Taschenbuch. Condition: Neu. Neuware -College students are particularly vulnerable to making poor financial decisions. One method of addressing personal finances and financial stress among students of higher education is through university based financial education programs. Student Financial Literacy: Program Development presents effective strategies to assist in the implementation or the enhancement of a program as a tool to improve studentsż educational experience and financial well-being. It presents the key components of financial education programs designed to address the growing concerns associated with high levels of debt and low levels of financial literacy among college students.żStudent Financial Literacy: Campus-Based Program Development is packed with financial education and counseling information and guidance. It was very difficult to write this review as I wanted to share ALL the excellent direction this book providesż The editors and contributing authors have developed an excellent resource for not only those interested in developing or enhancing a campus-based financial education program but also for anyone involved in financial education, counseling, and planning.ż -Rebecca J. Travnichek, Family Financial Education Specialist, University of Missouri Extension Journal of Financial Counseling and PlanningSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch.

Buch. Condition: Neu. Neuware -Interest in biofuels began with oil shocks in the 1970żs, but the more rapid development and consumption of biofuel industry in recent years has been primarily driven by mandates, subsidies, climate change concerns, emissions targets and energy security.From 2004 to 2006, fuel ethanol grew by 26% and biodiesel grew by 172%. As biofuel production continues to expand, investments in capacity expansion and research and development have been made. The 2008 food crisis emphasized the need to re-examine biofuel consequences. Biofuels remain an important renewable energy resource to substitute for fossil fuels, particularly in the transportation sector, yet biofuelsż success is still uncertain. The future of biofuels in the energy supply mix relies on mitigating potential and improving the environmental gains. This book brings together leading authorities on biofuel from the World Bank to examine all of the impacts of biofuel (economic, social, environmental) within a unified framework and in a global perspective, making it of interest to academics in agricultural and environmental economics as well as industry and policy-makers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 164 pp. Englisch.

Buch. Condition: Neu. Neuware -Modernizing Democracy brings together scholars focusing the role of associations and associating in contemporary societies. Organizations and associations have been identified as the żmeso level of societyż and as the żbasic elements of democracyż. They are important providers of welfare services and play an important role between the individual and political spheres. In recent years the environment of associations and associating has changed dramatically. Individualization, commercialization and globalization are challenging both democracy and the capability of associations to fulfill the functions attributed to them by social sciences. This change provides the central question of the volume: Is being part of an organization or association becoming an outdated model And do associations still have the capacity of modernizing societies or are they just outdated remnants of post-democracy The contributions to Modernizing Democracy will be organized into: Studying Association and Associating in the 21st Century, Associating in Times of Post-Democracy and Associations and the Challenge of Capitalist Development. The book will be attractive to third sector researchers as well as a broader academic community of political scientists, sociologists, economists, legal scientists and related disciplines.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 380 pp. Englisch.

Buch. Condition: Neu. Neuware -Malpractice settlements are large for undetected hydroxychloroquine and chloroquine toxicity which, if untreated, can lead to permanent loss of central vision. Knowledge of the ocular toxicity of these drugs has increased during the past fifty years as their use has expanded. Hydroxychloroquine and Chloroquine Retinopathy is the first single-source book on the subject and is essential for the practicing ophthalmologists, rheumatologists, dermatologists, and internists who prescribe these drugs. It covers clinical topics such as signs and symptoms of toxicity, toxicity screening, ancillary testing, to whom and why the drugs are prescribed and dosing considerations. Additionally, the book addresses practice management considerations, including coding, reimbursement and equipment costs, and the medico-legal responsibilities of the rheumatologist and of the ophthalmologist. Guidelines for the management of hydroxychloroquine and chloroquine vary around the world and differences between the guidelines of the United Kingdom, the United States, and other countries are identified. The book concludes with a collection of case examples illustrating common clinical scenarios and their management. This book is a żmust-haveż resource for physicians who use these drugs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Buch. Condition: Neu. Neuware -Neurovascular Coupling Methods brings the reader up to date with the current state-of-the-art techniques in measuring blood flow in the brain, with chapters describing different techniques or combinations of techniques, applied to specific species in either healthy or abnormal brains. Opening with a section on techniques in normal somatosensory processing, the detailed volume continues with parts covering techniques in normal visual processing, epilepsy and cerebrovascular diseases, such as ischemia, hemorrhage and spreading depression.As a collection in the popular Neuromethods series, this book contains the kind of thorough description and implementation advice that will lead to successful results in the lab.Authoritative and practical, Neurovascular Coupling Methods serves as an ideal guide for researchers aiming to further our knowledge of these coupling mechanisms in the hopes of ultimately understanding higher order functions such as language and memory and developing novel brain mapping techniques that can be employed in humans.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 352 pp. Englisch.

Buch. Condition: Neu. Neuware -The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approachfor practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Buch. Condition: Neu. Neuware -This book is comprised of selected research articles developed from a workshop on Ergodic Theory, Probabilistic Methods and Applications, held in April 2012 at the Banff International Research Station. It contains contributions from world leading experts in ergodic theory, numerical dynamical systems, molecular dynamics and ocean/atmosphere dynamics, nonequilibrium statistical mechanics. The volume will serve as a valuable reference for mathematicians, physicists, engineers, biologists and climate scientists, who currently use, or wish to learn how to use, probabilistic techniques to cope with dynamical models that display open or non-equilibrium behavior.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Buch. Condition: Neu. Neuware -Yeast Protocols, Third Edition presents up-to-date advances in research using yeasts as models. Chapters cover topics such as basic protocols in yeast culture and genomic manipulation, protocols that study certain organelles such as mitochondria and peroxisomes and their functions in autophagy and assays commonly used in yeast-based studies that can be adapted to other organisms. As the first sequenced living organism, budding yeast S. cerevisiae and other model yeasts have helped greatly in life science research. The easy switch between the haploid and diploid state makes yeast a paradigm of genetic manipulation. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Yeast Protocols, Third Edition seeks to serve both professionals and novices with newly-developed protocols to study this essential model organism.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 324 pp. Englisch.

Buch. Condition: Neu. Neuware -This book presents the developments in accelerator physics and technology implemented at the Tevatron proton-antiproton collider, the worldżs most powerful accelerator for almost twenty years prior to the completion of the Large Hadron Collider.The book covers the history of collider operation and upgrades, novel arrangements of beam optics and methods of orbit control, antiproton production and cooling, beam instabilities and feedback systems, halo collimation, and advanced beam instrumentation. The topics discussed show the complexity and breadth of the issues associated with modern hadron accelerators, while providing a systematic approach needed in the design and construction of next generation colliders.This book is a valuable resource for researchers in high energy physics and can serve as an introduction for students studying the beam physics of colliders.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 500 pp. Englisch.

Buch. Condition: Neu. Neuware -Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 240 pp. Englisch.

Buch. Condition: Neu. Neuware -Plant Cold Acclimation: Methods and Protocols details many of the methods and protocols commonly used to study plant cold acclimation and freezing tolerance, breeding, genetics, physiology or molecular biology, or any combination of these specialties. Chapters focus on interdisciplinary approaches, experimental methods, and concepts from different areas of science. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Plant Cold Acclimation: Methods and Protocols seeks to help not only new researchers starting in this field, but also those already working in a particular area of cold acclimation and freezing tolerance research who are looking to expand their range of experimental approaches.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 296 pp. Englisch.

Buch. Condition: Neu. Neuware -Engineering Multicellular Systems: Methods and Protocols, focuses on laboratory procedures used in recent efforts for constructing synthetic multicellular systems and their applications. In particular, constructing multicellular systems to form various microbial ecosystems has been extensively explored to examine evolution and interactions of microbial ecosystems, while co-cultures have emerged as an efficient tool to produce some complex chemical molecules. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls.Engineering Multicellular Systems: Methods and Protocols provide a comprehensive laboratory protocol reference for constructing multicellular systems for various applications.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 268 pp. Englisch.

Buch. Condition: Neu. Neuware -Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer. Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study.Written for the highly successful Methods in Molecular Biology series, chapters include introductions for their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 276 pp. Englisch.

Buch. Condition: Neu. Neuware -Clinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive care unit (ICU) patients in areas such as management of sepsis, fluid resuscitation, mechanical ventilation, antibiotic administration and sedation and analgesia. However, despite improved clinical care, many critically ill patients continue to experience complications of critical illness - some complications are iatrogenic and preventable, while others are simply a component of the natural history of critical illness. These complications lead to increased mortality, morbidity, cost and long-term chronic conditions. Non-Pulmonary Complications of Critical Care: A Clinical Guide is a valuable resource for trainees and clinicians who aim to better understand and improve the quality of critical care medicine. Armed with information about potential non-pulmonary complications of ICU care and strategies to minimize or prevent those complications, the critical care clinician will be able to help ICU patients potentially avoid much of the morbidity associated with critical illness. This book is organized by organ system such that it can be easily used as a bedside reference. Complications caused by pharmaceuticals are dispersed throughout every chapter and the concluding chapters provide a special emphasis on meticulous supportive care of the critically ill patient to allow the best chance for recovery.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 244 pp. Englisch.

Buch. Condition: Neu. Neuware -The chapters in this edited volume present multi-disciplinary case studies of prehistoric archaeological sites located on now-submerged portions of the continental shelf. Each chapter represents an extension of the known prehistoric record beyond the modern shoreline. Case studies represent central themes of landscape change, climate change and societal development, using new technologies for mapping, monitoring and managing these sites.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch.

Buch. Condition: Neu. Neuware -Just as autism is a continuum of disorders, it is associated with a broad range of neurodevelopmental, social, and communication deficits. For individuals with autism spectrum disorders (ASD), augmentative and alternative communication (AAC) has a major impact on their daily lives, often reducing the occurrence of challenging behaviors.Aided Augmentative Communication for Individuals with Autism Spectrum Disorders is a practical guide to the field, offering readers a solid grounding in ASD, related complex communication needs (CCN), and AAC, especially visual and computer-based technologies. Widely used interventions and tools in AAC are reviewedżnot just how they work, but why they workżto aid practitioners in choosing those most suited to individual clients or students. Issues in evaluation for aided AAC and debates concerning its usability round out the coverage. Readers come away with a deeper understanding of the centrality of communication for clients with ASD and the many possibilities for intervention.Key areas of coverage include:AAC and assessment of people with ASD and CCN.Interdisciplinary issues and collaboration in assessment and treatment.AAC intervention mediated by natural communication partners.Functional communication training with AAC.The controversy surrounding facilitated communication.Sign language versus AAC.Aided Augmentative Communication for Individuals with Autism Spectrum Disorders is an essential resource for clinicians/practitioners, researchers, and graduate students in such fields as child and school psychology, speech pathology, language education, developmental psychology, behavior therapy, and educational technology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 156 pp. Englisch.

Buch. Condition: Neu. Neuware -This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration. This volume in the Stem Cell Biology and Regenerative Medicine series is essential reading for stem cell biologists, ophthalmologists, advanced and graduate students, in addition to academics and medical staff who work in these disciplines.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 324 pp. Englisch.

Buch. Condition: Neu. Neuware -Plant Circadian Networks: Methods and Protocols provides a collection of protocols to investigate clock-controlled parameters including transcript and small RNA levels, promoter activity using luciferase reporters, protein levels and posttranslational modification, protein-protein interaction, in vivo DNA-protein interaction and RNA-protein interaction, cellular redox state, Ca2+ levels, and innate immune responses. Furthermore, the use of bioinformatics resources is described to evaluate high throughput data sets and to integrate the data into an overarching picture of circadian networks in the cell.Additional chapters focus on seasonal processes like flowering time control, and techniques on trees, moss and algae.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Plant Circadian Networks: Methods and Protocols is designed not only for the chronobiology community dealing with circadian biology but also for the plant community in general.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 376 pp. Englisch.

Buch. Condition: Neu. Neuware -Listeria monocytogenes is still a major threat to public health. A new book in the Methods in Molecular Biology series, Listeria monocytogenes: Methods and Protocols addresses its titular pathogen with protocols and methodologies used in research to gain a better understanding of Listeria at a molecular level. The topics covered include sampling in order to isolate Listeria, methods for their identification and characterization, methods for gene manipulation and finally, methods for control of the organism. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Vital and authoritative, Listeria monocytogenes: Methods and Protocols aims to contribute to the harmonization of the methods used in the field and will therefore benefit all those interested in Listeria research.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 296 pp. Englisch.

Buch. Condition: Neu. Neuware -Providing a list of methods useful both to those who wish to study pseudogenes and to those who actually want to avoid their inadvertent detection, Pseudogenes: Functions and Protocols explores techniques involving pseudogenic DNA, RNA, and peptides/proteins, once believed to lack any functionality, but now known to be involved in complex regulatory circuits. After a few introductory chapters that overview the functions so far attributed to pseudogenes, this thorough volume delves into methods for pseudogene identification, for the detection of pseudogene transcription and translation, and for the study of the functions of pseudogenic RNA and proteins, as well as methods to avoid pseudogene detection when the focus of the research is their highly homologous parental counterparts. As part of the highly successful Methods in Molecular Biology series, chapters feature the kind of detailed descriptions and implementation advice that ensures successful results in the lab.Authoritative and practical, Pseudogenes: Functions and Protocols will contribute to the high interest of the scientific community toward pseudogenes, while stimulating the conception of pseudogene - centered research projects and providing experimental protocols that can facilitate their execution.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 332 pp. Englisch.

Buch. Condition: Neu. Neuware -Commutative algebra, combinatorics, and algebraic geometry are thriving areas of mathematical research with a rich history of interaction. Connections Between Algebra and Geometry contains lecture notes, along with exercises and solutions, from the Workshop on Connections Between Algebra and Geometry held at the University of Regina from May 29-June 1, 2012. It also contains research and survey papers from academics invited to participate in the companion Special Session on Interactions Between Algebraic Geometry and Commutative Algebra, which was part of the CMS Summer Meeting at the University of Regina held June 2ż3, 2012, and the meeting Further Connections Between Algebra and Geometry, which was held at the North Dakota State University February 23, 2013. This volume highlights three mini-courses in the areas of commutative algebra and algebraic geometry: differential graded commutative algebra, secant varieties, and fat points and symbolic powers. It will serve as a useful resource for graduate students and researchers who wish to expand their knowledge of commutative algebra, algebraic geometry, combinatorics, and the intricacies of their intersection.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.

Taschenbuch. Condition: Neu. Neuware -We live in a complex and dynamically changing acoustic environment. To this end, the auditory cortex of humans has developed the ability to process a remarkable amount of diverse acoustic information with apparent ease. In fact, a phylogenetic comparison of auditory systems reveals that human auditory association cortex in particular has undergone extensive changes relative to that of other species, although our knowledge of this remains incomplete. In contrast to other senses, human auditory cortex receives input that is highly pre-processed in a number of sub-cortical structures; this suggests that even primary auditory cortex already performs quite complex analyses. At the same time, much of the functional role of the various sub-areas in human auditory cortex is still relatively unknown, and a more sophisticated understanding is only now emerging through the use of contemporary electrophysiological and neuroimaging techniques. The integration of results across the various techniques signify a new era in our knowledge of how human auditory cortex forms basis for auditory experience.This volume on human auditory cortex will have two major parts. In Part A, the principal methodologies currently used to investigate human auditory cortex will be discussed. Each chapter will first outline how the methodology is used in auditory neuroscience, highlighting the challenges of obtaining data from human auditory cortex; second, each methods chapter will provide two or (at most) three brief examples of how it has been used to generate a major result about auditory processing. In Part B, the central questions for auditory processing in human auditory cortex are covered. Each chapter can draw on all the methods introduced in Part A but will focus on a major computational challenge the system has to solve.This volume will constitute an important contemporary reference work on human auditory cortex. Arguably, this will be the first and most focused book on this critical neurological structure. The combination of different methodological and experimental approaches as well as a diverse range of aspects of human auditory perception ensures that this volume will inspire novel insights and spurn future research.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 412 pp. Englisch.

Buch. Condition: Neu. Neuware -Geriatric Urology outlines important topics in the care of elderly urology patients. The first section covers the biology of aging, the genitourinary system and disease screening including urologic conditions serving as warning signs of other disorders. Section two covers geriatric syndromes and urology including frailty, polypharmacy, dementia, wound healing, osteoporosis and endocrinology. Urologic conditions in older adults are explored in detail including urinary incontinence, pelvic organ prolapse, urinary tract infection, nocturia, and benign prostate diseases. Other topics covered include obtaining informed consent, development of advance directives, palliative medicine and care of the dying patient. Geriatric Urology is of great value to urologists, geriatricians, internists, residents and family practitioners.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 572 pp. Englisch.

Buch. Condition: Neu. Neuware -This volume examines the role of oxidative stress in the pathology of numerous pediatric disorders. It covers a wide range of topics including the chemistry and biology of reactive oxygen species and nitric oxide, molecular biology of the enzymes generating these species, clinically useful biomarkers for evaluating oxidative stress status in humans, and the pathophysiology, clinical course and management of a variety of pediatric disorders, among others. The book also describes current diagnostic tools, laboratory methods and technology for treatment and prevention of pediatric disorders. It explores emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents.Written by an international team of experts in both pediatrics and free radical and antioxidant research, Studies on Pediatric Disorders is an invaluable addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 508 pp. Englisch.

Buch. Condition: Neu. Neuware -With rapid advancement in technology and materials in total knee arthroplasty (TKA), long-term survival and function of the total knee is now more and more dependent on restoring accurate limb alignment, precise component position and optimum soft-tissue balance. Proper technique is key to ensuring this andis all the more crucial and challenging to achieve in arthritic knees with severe and complex deformities. Correction of such knee deformities forms an important part of TKA for orthopedic surgeons working in both emerging and developed nations.Deformity Correction in Total Knee Arthroplasty fills the void that exists in treating severe and complex knee deformities and the use of computer-navigation in TKA. It covers the principles of deformity correction and soft-tissue balancing in primary TKA in an illustrative, step-wise and algorithmic fashion. Starting with the initial key step of preoperative planning, this book goes on to specifically describe how to deal with different types of deformities encountered in patients who undergo TKA - varus,valgus, flexion,hypertension, rotational and extra-articular deformities - as well as the stiff knee, the unstable knee, osteotomies in primary TKA and postoperative pain management and rehabilitation. This focused how-to manual includesplentiful images and clear, concise text from authors who have performed thousands of TKAs, making it a must-have reference for any surgeon unfamiliar or frequently confronted with this type of procedure.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.