springer new york mai 2014 (90 results)

Buch. Condition: Neu. Neuware -In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics. 340 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Like everyone else, most amateur astronomers live busy lives. After a long day or work or looking after young children, the last thing you want as an observer is to have to lug out a large telescope and spend an hour getting it ready before it can be used. Maybe you are going on vacation somewhere in the countryside where there are sure to be dark skies, but you don't necessarily want astronomy to dominate the trip. Or suppose you are not quite committed to owning a large telescope, but curious enough to see what a smaller, portable setup can accomplish. These are times when a small 'grab 'n' go' telescope, or even a pair of binoculars, is the ideal instrument. And this book can guide you in choosing and best utilizing that equipment.What makes a telescope fall into the 'grab 'n' go' category That's easy - speed of setting up, ease of use, and above all, portability.In Part I of this book, we survey the various types of equipment, including accessories and mounts, that are available, and what it is best for what kind of viewing.Part II is about using your grab 'n' go telescope to visit a wealth and wide variety of objects. There are chapters on solar, lunar and planetary observing, as well as descriptions of many deep sky objects, including double and variable stars, planetary, emission and reflection nebulae, open and globular clusters and distant galaxies.This ambitious text is dedicated to those who love to or - because of their limited time - must observe the sky at a moment's notice, whether from the comfort of a backyard or while on business or vacation far from home. Everything you need to know is here. So get started! 260 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To the naked eye, the most evident defining feature of the planets is their motion across the night sky. It was this motion that allowed ancient civilizations to single them out as different from fixed stars. 'The Observer's Guide to Planetary Motion' takes each planet and its moons (if it has them) in turn and describes how the geometry of the Solar System gives rise to its observed motions.Although the motions of the planets may be described as simple elliptical orbits around the Sun, we have to observe them from a particular vantage point: the Earth, which spins daily on its axis and circles around the Sun each year. The motions of the planets as observed relative to this spinning observatory take on more complicated patterns. Periodically, objects become prominent in the night sky for a few weeks or months, while at other times they pass too close to the Sun to be observed. 'The Observer's Guide to Planetary Motion' provides accurate tables of the best time for observing each planet, together with other notable events in their orbits, helping amateur astronomers plan when and what to observe. Uniquely each of the chapters includes extensive explanatory text, relating the events listed to the physical geometry of the Solar System.Along the way, many questions are answered: Why does Mars take over two years between apparitions (the times when it is visible from Earth) in the night sky, while Uranus and Neptune take almost exactly a year Why do planets appear higher in the night sky when they're visible in the winter months Why do Saturn's rings appear to open and close every 15 years This book places seemingly disparate astronomical events into an understandable three-dimensional structure, enabling an appreciation that, for example, very good apparitions of Mars come around roughly every 15 years and that those in 2018 and 2035 will be nearly as good as that seen in 2003.Events are listed for the time period2010-2030 and in the case of rarer events (such as eclipses and apparitions of Mars) even longer time periods are covered. A short closing chapter describes the seasonal appearance of deep sky objects, which follow an annual cycle as a result of Earth's orbital motion around the Sun. 256 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Mathematics of Finance has been a hot topic ever since the discovery of the Black-Scholes option pricing formulas in 1973. Unfortunately, there are very few undergraduate textbooks in this area. This book is specifically written for advanced undergraduate or beginning graduate students in mathematics, finance or economics. This book concentrates on discrete derivative pricing models, culminating in a careful and complete derivation of the Black-Scholes option pricing formulas as a limiting case of the Cox-Ross-Rubinstein discrete model.This second edition is a complete rewrite of the first edition with significant changes to the topic organization, thus making the book flow much more smoothly. Several topics have been expanded such as the discussions of options, including the history of options, and pricing nonattainable alternatives. In this edition the material on probability has been condensed into fewer chapters, and the material on the capital asset pricing model has been removed.The mathematics is not watered down, but it is appropriate for the intended audience. Previous knowledge of measure theory is not needed and only a small amount of linear algebra is required. All necessary probability theory is developed throughout the book on a 'need-to-know' basis. No background in finance is required, since the book contains a chapter on options. 304 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Case Studies in Service Innovation provides the reader fresh insight into how innovation occurs in practice, and stimulates learning from one context to another. The volume brings together contributions from researchers and practitioners in a celebration of achievements with the intention of adding to the wider understanding of how service innovation develops. Each case presents a brief description of the context in which the innovation occurred, the opportunity that led to the innovation and an overview of the innovation itself, also addressing how success was measured, what success has been achieved to date and providing links to further information. The book is organized around five major themes, each reflecting recognized sources of service innovation: Business Model Innovation: new ways of creating, delivering or capturing economic, social, environmental and other types of value; The Organization in its Environment: an organization engaging beyond its own boundaries, with public private partnerships, sourcing knowledge externally, innovation networks, and open or distributed innovation; Innovation Management within an Organization: an organization actively encouraging innovation within its own boundaries using project teams, internal governance of innovation, and methods or tools that stimulate innovation; Process Innovation: changes in service design and delivery processes, such as consumer led innovation or consumers as part of the innovation process, service operations management, and educational processes; Technology Innovation: the use of technology, including ICT enabled innovation, ICTs that are themselves innovative and support the delivery of new services, new ICT services, new ways of delivering services associated with ICT products, and technology other than ICT. The final part of the book is given to four extended cases allowing for a more in-depth treatment of innovation within a complex service system. The extended cases also illustrate two important and growing trends, firstly the need for, and benefits of, a more customer centric approach to service innovation and secondly the need for better understanding of public services and the role of public-private partnerships in identifying and achieving innovation. 248 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Health care is a very important component of the American economy. The United States Centers for Medicare and Medicaid Services (CMS) put the 2008 direct health care expenditures at about $2.34 trillion, or about 16.2 percent of the nation's gross domestic product (GDP), or an average of $7,681 spent for every man, woman, and child in the country. Health care cost increases have caused very serious problems that threaten to bankrupt the system, providers, employers, and the families that pay the costs that their health insurance plans do not cover. Additionally, cost increases have reduced access to health care services, adversely affected the quality of care, and resulted in avoidable illnesses, premature deaths, and in health disparities based on race, ethnicity, and income. Consequently, health care reform has continuously been on the public and governmental agendas. It is out of this environment that several reform plans, including the 1993 Health Security Act, and the 2010 Patient Protection and Affordable Care Act (PPACA), were launched. This book examines the ideological, social, cultural, economic, and several other factors that dictate the various measures and approaches employed to tackle the perceived problems. The book has an index, tables, charts and figures, lists of major terms, and review questions for each chapter. This book will appeal to students in Master of Health Administration (MHA), Master of Public Health (MPH), Master of Public Administration (MPA), Master of Science in Nursing (MSN), health certificate programs, and junior and senior level undergraduate students in political science, public administration, public health, and public policy. In addition to serving as a core text for health policy and administration classes, the book will serve as a supplementary text for graduate level courses. 312 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book covers some biostatistical methods and several case studies useful to interpret and analyze dental research in the areas of orofacial pain and temporomandibular disorders. It will guide practitioners in these fields who would like to interpret research findings or find examples on the design of clinical investigations. After an introduction dealing with the basic issues, the central sections of the textbook are dedicated to the different types of investigations in sight of specific goals researchers may have. The final section contains a recent approach based on nonparametric permutation tests which can be adopted in many practical situations. The field of orofacial pain and temporomandibular disorders is emerging as one of the most critical areas of clinical research in dentistry. Due to the complexity of clinical pictures, the multifactorial etiology, and the importance of psychosocial factors in all aspects of the TMD practice, clinicians often find it hard to appraise their modus operandi, and researchers must constantly increase their knowledge in epidemiology and medical statistics. Indeed, proper methodological designs are fundamental to reaching high levels of internal and external validity of findings in this specific area. 92 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cloud Computing Basics covers the main aspects of this fast moving technology so that both practitioners and students will be able to understand cloud computing. The author highlights the key aspects of this technology that a potential user might want to investigate before deciding to adopt this service. This book explains how cloud services can be used to augment existing services such as storage, backup and recovery. Addressing the details on how cloud security works and what the users must be prepared for when they move their data to the cloud. Also this book discusses how businesses could prepare for compliance with the laws as well as industry standards such as the Payment Card Industry. 160 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This SpringerBrief summarizes a full-scale, reduced commodity fire testing comparison of cartoned Lithium ion batteries and FM Global standard commodities in a rack storage configuration, as reported by FM Global. Tests evaluate the flammability characteristics of the materials and the effectiveness of ceiling level only sprinkler protection. The testing methods, discussed in depth, are scaled down from standard commodity classification testing due to the inordinate costs of Li-ion batteries. Small format Li-ion battery commodities represent both commercially available battery formats and Li-ion battery containing devices. The selected Li-ion battery types are individual 18650 format cylindrical cells, power tool packs comprised of 18650 format cells and polymer cells. The selected comparison commodities are the FM Global standard Class 2 and Cartoned Unexpanded Plastic (CUP). The results offer insight into the combined effects of different storage heights, ceiling height, protection system design, battery density, state of charge and battery type. Flammability of Cartoned Lithium Ion Batteries is intended for practitioners as a tool for analyzing commodity testing methods and providing data about potential hazards. Researchers working in a related field will also find the book valuable. 52 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals specific to the metabolomics community. This book will be particularly useful for post-graduate students and post-doctoral researchers using this pioneering technique of network-based correlation analysis. The approach can be adapted to the analysis of any large scale metabolic profiling experiment to answer a range of biological questions in a range of species or for a range of diseases. 68 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This SpringerBrief explores the evacuation characteristics of children and their self-preservation capability during fire situations. An international survey among teachers from day-care centers and experts in child development indicates an age-limit at which pre-school children may be considered capable of evacuating a location without direct intervention by an instructor. The survey examines the ability of children to understand and follow simple instructions, walk on horizontal surfaces without physical support, and walk down stairs. It also studies how fire safety installations and fire drills differ between countries. A literature review and a presentation of the method applied are included. This data can be applied to evacuation procedures, building codes, and fire regulations. Determining Self-Preservation Capability in Pre-School Children is intended for practitioners as a tool for analyzing evacuation safety issues and developing methods removing potential hazards. Researchers working in a related field will also find the book valuable. 60 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Patient Preparation for Bariatric Surgery provides a comprehensive and state of the art review of all aspects of the patient preparation process, The text reviews current literature and controversies involving sources of referrals and the difficulties encountered by primary care physicians in managing patients with extreme obesity. Strategies for addressing this problem and integrating primary care physicians in comprehensive obesity programs are presented. The text also reviews current indications for surgery and the current patient access limitations that have resulted in the need for revised surgical indications based more on medical need than mere extent of obesity.Written by an authority in the field, Patient Preparation for Bariatric Surgery is a valuable resource for bariatric surgeons, bariatric physicians and all allied health personnel who manage patients with extreme obesity and will assist in the advancement of this area of surgery as well as stimulate new discovery. 172 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume reviews the theory and simulation methods of stochastic kinetics by integrating historical and recent perspectives, presents applications, mostly in the context of systems biology and also in combustion theory. In recent years, due to the development in experimental techniques, such as optical imaging, single cell analysis, and fluorescence spectroscopy, biochemical kinetic data inside single living cells have increasingly been available. The emergence of systems biology brought renaissance in the application of stochastic kinetic methods. 176 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This SpringerBrief focuses on the use of egress models to assess the optimal strategy for total evacuation in high-rise buildings. It investigates occupant relocation and evacuation strategies involving the exit stairs, elevators, sky bridges and combinations thereof. Chapters review existing information on this topic and describe case study simulations of a multi-component exit strategy. This review provides the architectural design, regulatory and research communities with a thorough understanding of the current and emerging evacuation procedures and possible future options. A model case study simulates seven possible strategies for the total evacuation of two identical twin towers linked with two sky-bridges at different heights. The authors present the layout of the building and the available egress components including both vertical and horizontal egress components, namely stairs, occupant evacuation elevators (OEEs), service elevators, transfer floors and sky-bridges. The evacuation strategies employ a continuous spatial representation evacuation model (Pathfinder) and are cross-validated by a fine network model (STEPS). Assessment of Total Evacuation Systems for Tall Buildings is intended for practitioners as a tool for analyzing evacuation methods and efficient exit strategies. Researchers working in architecture and fire safety will also find the book valuable. 68 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book gives a survey of astrophysics at the advanced undergraduate level, providing a physics-centred analysis of a broad range of astronomical systems. It originates from a two-semester course sequence at Rutgers University that is meant to appeal not only to astrophysics students but also more broadly to physics and engineering students.The organisation is driven more by physics than by astronomy; in other words, topics are first developed in physics and then applied to astronomical systems that can be investigated, rather than the other way around.The first half of the book focuses on gravity. The theme in this part of the book, as well as throughout astrophysics, is using motion to investigate mass. The goal of Chapters 2-11 is to develop a progressively richer understanding of gravity as it applies to objects ranging from planets and moons to galaxies and the universe as a whole. The second half uses other aspects of physics to address one of the bigquestions. While 'Why are we here ' lies beyond the realm of physics, a closely related question is within our reach: 'How did we get here ' The goal of Chapters 12-20 is to understand the physics behind theremarkable story of how the Universe, Earth and life were formed. This book assumes familiarity with vector calculus and introductory physics (mechanics, electromagnetism, gas physics and atomic physics); however, all of the physics topics are reviewed as they come up (and vital aspects of vector calculus are reviewed in the Appendix). 456 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -College students are particularly vulnerable to making poor financial decisions. One method of addressing personal finances and financial stress among students of higher education is through university based financial education programs. Student Financial Literacy: Program Development presents effective strategies to assist in the implementation or the enhancement of a program as a tool to improve students' educational experience and financial well-being. It presents the key components of financial education programs designed to address the growing concerns associated with high levels of debt and low levels of financial literacy among college students.'Student Financial Literacy: Campus-Based Program Development is packed with financial education and counseling information and guidance. It was very difficult to write this review as I wanted to share ALL the excellent direction this book provides. The editors and contributing authors have developed an excellent resource for not only those interested in developing or enhancing a campus-based financial education program but also for anyone involved in financial education, counseling, and planning.'-Rebecca J. Travnichek, Family Financial Education Specialist, University of Missouri ExtensionJournal of Financial Counseling and Planning 208 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To satisfy the higher requirements of digitally converged embedded systems, this book describes heterogeneous multicore technology that uses various kinds of low-power embedded processor cores on a single chip. With this technology, heterogeneous parallelism can be implemented on an SoC, and greater flexibility and superior performance per watt can then be achieved. This book defines the heterogeneous multicore architecture and explains in detail several embedded processor cores including CPU cores and special-purpose processor cores that achieve highly arithmetic-level parallelism. The authors developed three multicore chips (called RP-1, RP-2, and RP-X) according to the defined architecture with the introduced processor cores. The chip implementations, software environments, and applications running on the chips are also explained in the book.Provides readers an overview and practical discussion of heterogeneous multicore technologies from both a hardware and software point of view;Discusses a new, high-performance and energy efficient approach to designing SoCs for digitally converged, embedded systems;Covers hardware issues such as architecture and chip implementation, as well as software issues such as compilers, operating systems, and application programs;Describes three chips developed according to the defined heterogeneous multicore architecture, including chip implementations, software environments, and working applications. 236 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is written for ecologists interested in capturing their understandings of how natural systems work in software - to help inform their work and communicate the consequences of proposed management plans. Historically, ecologists had to rely on the skills of trained computer programmers to modeling natural systems, but now a new generation of software is allowing ecologists to directly capture their understandings of systems in software. This book is a compilation of spatially explicit simulation models developed by ecologists and planners without any formal computer programming skills. Readers will be inspired to believe that they too can create similar models of the systems with which they are familiar. 280 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Full-scale political change affects every level of a society, but perhaps nowhere as strikingly as in the areas of crime policy and law enforcement. Over the past two decades, the European nations that have moved from totalitarianism toward democracy have come to embody this trend, yet reliable sources on crime and law enforcement in these countries have not been readily accessible to the West.Representing viewpoints seldom available to outsiders, the contributors to Crime and Transition in Central and Eastern Europe analyze changes in criminal activities and crime control strategies in the region, explain the political background underlying these developments, and assess their long-term social impact. Experts from Slovenia, Hungary, Croatia, Serbia, the Czech Republic, Poland, Bosnia and Herzegovina discuss the politicization of crime, the ongoing paradoxes regarding civil liberties, and the future of crime policy in comparative and country-specific terms. Among the topics featured in the book: Crime and crime control in transitional countries, politics, the media, and public perception of crime, surveillance: from national security to private industry, penal policy and political change, emerging trends: economic and organized crime, human trafficking, juvenile delinquency, new perspectives on corruption in the region.With this fascinating insight, Crime and Transition in Central and Eastern Europe is a singular reference for researchers and policymakers in criminology and political science, and historians with a special interest in European affairs and policy. 308 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Interest in biofuels began with oil shocks in the 1970's, but the more rapid development and consumption of biofuel industry in recent years has been primarily driven by mandates, subsidies, climate change concerns, emissions targets and energy security. From 2004 to 2006, fuel ethanol grew by 26% and biodiesel grew by 172%. As biofuel production continues to expand, investments in capacity expansion and research and development have been made. The 2008 food crisis emphasized the need to re-examine biofuel consequences. Biofuels remain an important renewable energy resource to substitute for fossil fuels, particularly in the transportation sector, yet biofuels' success is still uncertain. The future of biofuels in the energy supply mix relies on mitigating potential and improving the environmental gains. This book brings together leading authorities on biofuel from the World Bank to examine all of the impacts of biofuel (economic, social, environmental) within a unified framework and in a global perspective, making it of interest to academics in agricultural and environmental economics as well as industry and policy-makers. 164 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Economic growth of a country depends on its industries. The focus of modern growth theory is basically macroeconomics, although neoclassical models use competitive markets and the optimization behavior of households and firms in general equilibrium framework. The emphasis here is on industry growth, where the microfoundations of industry are analyzed in terms of economic efficiency. The various linkages which link firm growth with the industry growth are discerned here under various market structures both competitive and monopolistic. The role of information in facilitating market signals and allowing the adoption of new processes has been especially emphasized in this volume. Many issues of market failure and the suboptimality of competitive equilibria are due to incomplete and imperfect information structures and we need a comprehensive theory of information structures underlying the process of industry growth and its dynamics. This book will be of interest to economists studying economic and industry growth and innovation. 188 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Modernizing Democracy brings together scholars focusing the role of associations and associating in contemporary societies. Organizations and associations have been identified as the 'meso level of society' and as the 'basic elements of democracy'. They are important providers of welfare services and play an important role between the individual and political spheres. In recent years the environment of associations and associating has changed dramatically. Individualization, commercialization and globalization are challenging both democracy and the capability of associations to fulfill the functions attributed to them by social sciences. This change provides the central question of the volume: Is being part of an organization or association becoming an outdated model And do associations still have the capacity of modernizing societies or are they just outdated remnants of post-democracy The contributions to Modernizing Democracy will be organized into: Studying Association and Associating in the 21st Century, Associating in Times of Post-Democracy and Associations and the Challenge of Capitalist Development. The book will be attractive to third sector researchers as well as a broader academic community of political scientists, sociologists, economists, legal scientists and related disciplines. 380 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This research monograph summarizes a line of research that maps certain classical problems of discrete mathematics and operations research - such as the Hamiltonian Cycle and the Travelling Salesman Problems - into convex domains where continuum analysis can be carried out. Arguably, the inherent difficulty of these, now classical, problems stems precisely from the discrete nature of domains in which these problems are posed. The convexification of domains underpinning these results is achieved by assigning probabilistic interpretation to key elements of the original deterministic problems. In particular, the approaches summarized here build on a technique that embeds Hamiltonian Cycle and Travelling Salesman Problems in a structured singularly perturbed Markov decision process. The unifying idea is to interpret subgraphs traced out by deterministic policies (including Hamiltonian cycles, if any) as extreme points of a convex polyhedron in a space filled with randomized policies.The above innovative approach has now evolved to the point where there are many, both theoretical and algorithmic, results that exploit the nexus between graph theoretic structures and both probabilistic and algebraic entities of related Markov chains. The latter include moments of first return times, limiting frequencies of visits to nodes, or the spectra of certain matrices traditionally associated with the analysis of Markov chains. However, these results and algorithms are dispersed over many research papers appearing in journals catering to disparate audiences. As a result, the published manuscripts are often written in a very terse manner and use disparate notation, thereby making it difficult for new researchers to make use of the many reported advances.Hence the main purpose of this book is to present a concise and yet easily accessible synthesis of the majority of the theoretical and algorithmic results obtained so far. In addition, the book discusses numerous open questions and problems that arise from this body of work and which are yet to be fully solved. The approach casts the Hamiltonian Cycle Problem in a mathematical framework that permits analytical concepts and techniques, not used hitherto in this context, to be brought to bear to further clarify both the underlying difficulty of NP-completeness of this problem and the relative exceptionality of truly difficult instances. Finally, the material is arranged in such a manner that the introductory chapters require very little mathematical background and discuss instances of graphs with interesting structures that motivated a lot of the research in this topic. More difficult results are introduced later and are illustrated with numerous examples. 216 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Exploring these type II trans-membrane proteins, The TNF Superfamily: Methods and Protocols focuses on various techniques to investigate aspects of the TNF Superfamily members in health and disease. Opening with protocols to understand the signaling process of TNF family members, this detailed volume continues with technical examples of investigating the role of TNF family members in physiopathologies, protocols on modulation of TNF signaling by pathogens, experimental applications of TNF-reporter mice, as well as methodologies for various assays of TNF family members and the production of recombinant molecules. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Practical and ready to use, The TNF Superfamily: Methods and Protocols will aid researchers investigating this key family of proteins, involved in vital processes such as providing signals for activation, differentiation, survival and death of cells, modulation of immune response and inflammation, hematopoiesis and osteoclastogenesis. 240 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Plant Cold Acclimation: Methods and Protocols details many of the methods and protocols commonly used to study plant cold acclimation and freezing tolerance, breeding, genetics, physiology or molecular biology, or any combination of these specialties. Chapters focus on interdisciplinary approaches, experimental methods, and concepts from different areas of science. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Plant Cold Acclimation: Methods and Protocols seeks to help not only new researchers starting in this field, but also those already working in a particular area of cold acclimation and freezing tolerance research who are looking to expand their range of experimental approaches. 296 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Optimization in Science and Engineering is dedicated in honor of the 60th birthday of Distinguished Professor Panos M. Pardalos. Pardalos's past and ongoing work has made a significant impact on several theoretical and applied areas in modern optimization. As tribute to the diversity of Dr. Pardalos's work in Optimization, this book comprises a collection of contributions from experts in various fields of this rich and diverse area of science.Topics highlight recent developments and include:Deterministic global optimizationVariational inequalities and equilibrium problemsApproximation and complexity in numerical optimizationNon-smooth optimization Statistical models and data miningApplications of optimization in medicine, energy systems, and complex network analysisThis volume will be of great interest to graduate students, researchers, and practitioners, in the fields of optimization and engineering. 624 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents the developments in accelerator physics and technology implemented at the Tevatron proton-antiproton collider, the world's most powerful accelerator for almost twenty years prior to the completion of the Large Hadron Collider. The book covers the history of collider operation and upgrades, novel arrangements of beam optics and methods of orbit control, antiproton production and cooling, beam instabilities and feedback systems, halo collimation, and advanced beam instrumentation. The topics discussed show the complexity and breadth of the issues associated with modern hadron accelerators, while providing a systematic approach needed in the design and construction of next generation colliders. This book is a valuable resource for researchers in high energy physics and can serve as an introduction for students studying the beam physics of colliders. 500 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph explores nonoscillation and existence of positive solutions for functional differential equations and describes their applications to maximum principles, boundary value problems and stability of these equations. In view of this objective the volume considers a wide class of equations including, scalar equations and systems of different types, equations with variable types of delays and equations with variable deviations of the argument. Each chapter includes an introduction and preliminaries, thus making it complete. Appendices at the end of the book cover reference material. Nonoscillation Theory of Functional Differential Equations with Applications is addressed to a wide audience of researchers in mathematics and practitioners. 536 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer. Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions for their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment. 276 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Engineering Multicellular Systems: Methods and Protocols, focuses on laboratory procedures used in recent efforts for constructing synthetic multicellular systems and their applications. In particular, constructing multicellular systems to form various microbial ecosystems has been extensively explored to examine evolution and interactions of microbial ecosystems, while co-cultures have emerged as an efficient tool to produce some complex chemical molecules. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls.Engineering Multicellular Systems: Methods and Protocols provide a comprehensive laboratory protocol reference for constructing multicellular systems for various applications. 268 pp. Englisch.