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Add to basketCondition: Very Good. [ No Hassle 30 Day Returns ][ Ships Daily ] [ Underlining/Highlighting: NONE ] [ Writing: NONE ] [ Edition: Reprint ] Publisher: Springer Pub Date: 3/2/2023 Binding: Hardcover Pages: 384 Reprint edition.
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Published by Springer Nature Singapore, Springer Nature Singapore, 2020
ISBN 10: 9811568146 ISBN 13: 9789811568145
Language: English
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Add to basketBuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling.Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
Published by Springer, Berlin|Springer Nature Singapore|Springer, 2024
ISBN 10: 9811982511 ISBN 13: 9789811982514
Language: English
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