Neuware - In the present thesis, pharmacometric modelling methodologies were applied to determine the pharmacokinetics of sibrotuzumab, a humanised therapeutic monoclonal antibody, and to account for the in uence of immunogenicity. Furthermore, design factors in uencing the identi ability of model parameters characterising monoclonal antibody pharmacokinetics were investigated using a simulation-based approach. 262 pp. Englisch. Bookseller Inventory # 9783844026504
Title: Population Pharmacokinetic Modelling and ...
Publisher: Shaker Verlag Mrz 2014
Publication Date: 2014
Book Condition: Neu
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