Phosphodiesterases as Drug Targets
Sharron H. Francis
From BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
AbeBooks Seller Since 11 January 2012
Quantity: 2From BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
AbeBooks Seller Since 11 January 2012
Quantity: 2About this Item
This item is printed on demand - it takes 3-4 days longer - Neuware -Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors. 540 pp. Englisch. Seller Inventory # 9783642179686
Bibliographic Details
Title: Phosphodiesterases as Drug Targets
Publisher: Springer Berlin Heidelberg Aug 2011
Publication Date: 2011
Binding: Buch
Condition: Neu
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