NF-kB in Health and Disease

Michael Karin

Published by Springer Mai 2011, 2011
ISBN 10: 3642160166 / ISBN 13: 9783642160165
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Neuware - Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation 276 pp. Englisch. Bookseller Inventory #

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Synopsis: Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology―from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

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This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-kB. Articles in the volume, all of them written by the leading experts in the field, range from description of the NF-kB system and its basic components, its logic and its transcriptional regulatory functions to its participation in diverse processes, including inflammation, immunity, mucosal homeostasis and cancer. In addition to discussing the molecular biology and physiology of the NF-kB system, this volume also addresses the therapeutic targeting of NF-kB and its regulators. Thus, this volume is an important reading to both basic and translational scientists interested in different aspects of this highly versatile regulatory system.

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Title: NF-kB in Health and Disease
Publisher: Springer Mai 2011
Publication Date: 2011
Binding: Buch
Book Condition: Neu

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