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Mammalian Brain Development

Published by Humana Press Inc.
ISBN 10: 1617796484 / ISBN 13: 9781617796487
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Bibliographic Details

Title: Mammalian Brain Development

Publisher: Humana Press Inc.

Binding: Soft cover

Book Condition: New


By focusing on both the pre-natal and the peri-natal events that lead to brain damage, this book fills a gap in developmental books dealing with the normal prenatal mammalian brain. It also covers aspects of postnatal and pediatric neurological disorders. Editor(s): Janigro, Damir. Series: Contemporary Neuroscience. Num Pages: 241 pages, 31 black & white illustrations, 12 black & white tables, biography. BIC Classification: MJN; PSAK. Category: (G) General (US: Trade). Dimension: 235 x 155 x 13. Weight in Grams: 379. . 2012. 2009th Edition. Paperback. . . . . Books ship from the US and Ireland. Bookseller Inventory # V9781617796487

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Synopsis: Denis Noble Nearly a decade after completion of the first draft of the entire Human Genome sequence we are in a better position to assess the nature and the consequences of that heroic achievement, which can be seen as the culmination of the molecular biological revolution of the second half of the twentieth century. The achievement itself was celebrated at the highest levels (President and Prime Minister) on both sides of the Atlantic, and rightly so. DNA sequencing has become sufficiently c- mon now, even to the extent of being used in law courts, that it is easy to forget how technically difficult it was and how cleverly the sequencing teams solved those problems in the exciting race to finish by the turn of the century [1, 2]. The fanfares were misplaced, however, in an important respect. The metaphors used to describe the project and its biological significance gave the impression to the public at large, and to many scientists themselves, that this sequence would reveal the secrets of life. DNA had already been likened to a computer program [3]. The ?genetic program? for life was therefore to be found in those sequences: A kind of map that had simply to be unfolded during development. The even more colo- ful ?book of life? metaphor gave the promise that reading that book would lead to a veritable outpouring of new cures for diseases, hundreds of new drug targets, and a brave new world of medicine.

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This book fills a gap in developmental books dealing with the normal prenatal mammalian brain. Most books that approach this topic work with non-human, non-vertebrate models. Mammalian Brain Development focuses on both the pre-natal and the peri-natal events that lead to brain damage as seen in the prospective of medical and research professionals, as well as examining the traditional ?nature versus nurture? argument in the spectrum of brain development. The major topics addressed, in detail, in the book are sexual dimorphism, epigenetic action of gonadal hormones, environmental ?programming? effects, autism, developmental learning disorders, seizures, and the etiopathogenesis of epileptic syndromes in young humans. The book also covers the general aspects of postnatal and pediatric neurological disorders in a unique and novel way by offering definitions of heredity, inheritance, genetic-epigenetic, genomic, molecular, developmental, and innate aspects of the mammalian brain in regards to its development.

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